Comparing a New Technique of Combining Carbon-dioxide With Electrocautery With Usual Technique of Stand-alone Electrocautery for Taking Down Left Internal Mammary Artery for Coronary Artery Bypass(CABG)

Coronary Artery Disease Clinical Trial

— CABG  

Official title:

A Comparative Study Between Conventional & Modified Carbo-dissection Techniques for LIMA Harvesting in CABG Patients

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT06155045
• Other study ID #: 95/2020
• Status: Completed
• Phase: N/A
• Start date: January 1, 2021
• Est. completion date: December 31, 2021

Study information

• Verified date: December 2023
• Source: Government Medical College Kottayam
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The goal of this study is to compare the efficacy of a new harvesting technique for an arterial conduit(LIMA - Left Internal Mammary artery) in patients undergoing Coronary artery bypass grafting. The researcher will compare the

1. Time taken to harvest the artery

2. Flow of blood between the two techniques

Description:

Following consultation to our department, after a detailed history and clinical examination,patients with CAD, being planned for CABG, will be subjected to a detailed pre-op Echocardiogram and coronary angiogram. After necessary pre-op assessment, patient will be taken up for the surgery. Invasive monitoring will be done.

Following dissection of LIMA by the above mentioned technique, flow of blood from the harvested LIMA, for one whole minute is noted. The operative time required for the dissection of LIMA will be noted and entered.

The data between the two techniques will be compared statistically.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 46
• Est. completion date: December 31, 2021
• Est. primary completion date: December 31, 2021
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 80 Years

Eligibility

Inclusion Criteria:

1. Elective CABG

2. Hemodynamically stable CAD patients

Exclusion Criteria:

1. Re-operation, previous sternotomy (where LIMA is already dissected)

2. concomitant valve operation, ventricular aneurysm resection

3. other additional major cardiac procedures

4. Patients with chronic obstructive pulmonary disease

Related Conditions & MeSH terms

• Coronary Artery Disease
• Coronary Artery Disease With Myocardial Infarction
• Coronary Disease
• Infarction
• Myocardial Infarction
• Myocardial Ischemia

Intervention

Procedure:
• Modified Carbo-dissection Technique
This technique comes the C02 blower with electrocautery. Thereby, producing vasodilatation due to the gas and dissection aided by the electrocautery.
• Conventional Arm
This technique uses only the electrocautery as conventional model

Locations

Country	Name	City	State
India	Government Medical College Kottayam	Kottayam	Kerala

Sponsors (1)

Lead Sponsor	Collaborator
Government Medical College Kottayam

Country where clinical trial is conducted

India, 

References & Publications (3)

Gilbert S, Singh D, Sivakumar MK. Modified carbodissection: A new technique for harvesting the internal mammary artery. Multimed Man Cardiothorac Surg. 2017 Oct 29;2017. doi: 10.1510/mmcts.2017.018. — View Citation

Lee ME. Carbodissection of the internal thoracic artery pedicle. Ann Thorac Surg. 1988 Oct;46(4):470-1. doi: 10.1016/s0003-4975(10)64671-1. — View Citation

Ozkan M, Koramaz I, Ulus AT, Tavil Y, Filizlioglu H, Baykan EC, Eryilmaz S, Inan B, Katircioglu SF, Ozyurda U. Effect of carbon dioxide insufflation on free internal thoracic artery flows: is it a vasodilator? J Thorac Cardiovasc Surg. 2004 Sep;128(3):354-6. doi: 10.1016/j.jtcvs.2003.11.006. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Operative time	Time taken to perform the harvesting of the LIMA	10-20 min
Primary	Blood flow/min	Post dividing of the LIMA: blood from the LIMA is measured for 1 min	1 min