Clinical Trials Logo
  1. Home
  2. Coronary Artery Disease
  3. NCT05775354
  4. Details
NCT05775354 Clinical Trial

Reviving Early Diagnosis of Cardiovascular Disease in the Utrecht Health Project

Coronary Artery Disease Clinical Trial

— RED-LRGP  

Official title:
Reviving Early Diagnosis of Cardiovascular Disease in the Utrecht Health Project

Clinical Trial Details — Status: Enrolling by invitation

Administrative data
NCT number NCT05775354
Other study ID # NL82944.041.23
Secondary ID
Status Enrolling by invitation
Phase N/A
First received
Last updated
Start date November 1, 2023
Est. completion date October 2026

Study information
Verified date February 2024
Source UMC Utrecht
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

The goal of this randomized trial is to compare the diagnostic yield of a screen-like early diagnosis strategy to usual primary care to detect coronary artery disease (CAD), atrial fibrillation (AF), heart failure (HF), and/or valvular heart disease (VHD) in community people aged 50-80 years who participate in the Utrecht Health Project. The diagnosis strategy consists of a questionnaire with questions related to symptoms suggestive of CAD, AF or HF, a focused physical examination, laboratory testing, electrocardiography, and echocardiography.

Recruitment information / eligibility
Status Enrolling by invitation
Enrollment 1476
Est. completion date October 2026
Est. primary completion date May 2026
Accepts healthy volunteers No
Gender All
Age group 50 Years to 80 Years
Eligibility Inclusion Criteria: - Aged 50-80 years - Being a participant of LRGP - Having indicated in the LRGP informed consent to be interested in participating in further research. Exclusion Criteria: - Diagnosed with coronary artery disease and atrial fibrillation and heart failure. - Undergoing major (cardiovascular) surgery, and/or revascularisation therapy and/or transplantation treatment within 3 months after enrolment. - Not willing to give written informed consent for RED-LRGP. - Not allowing incidental findings to be reported to him/herself or their own GP.

Study Design

Related Conditions & MeSH terms

Intervention

Diagnostic Test:
• Early diagnosis strategy
RED-CVD early diagnosis questionnaire, physical examination, laboratory testing, electrocardiography, echocardiography

Locations
Country Name City State
Netherlands UMC Utrecht Utrecht

Sponsors (1)
Lead Sponsor Collaborator
UMC Utrecht

Country where clinical trial is conducted

Netherlands, 

Outcome
Type Measure Description Time frame Safety issue
Primary Coronary artery disease 1 year
Primary Atrial fibrillation 1 year
Primary Heart failure 1 year
Primary Valvular heart disease 1 year
Secondary Echocardiographic abnormalities 1 year
Secondary Health-related quality of life 1 year
Secondary CVD family history and women's reproductive history 1 year
Secondary Cardiovascular risk profile 1 year
Secondary Costs 1 year
See also
  Status Clinical Trial Phase
Recruiting NCT06030596 - SPECT Myocardial Blood Flow Quantification for Diagnosis of Ischemic Heart Disease Determined by Fraction Flow Reserve
Completed NCT04080700 - Korean Prospective Registry for Evaluating the Safety and Efficacy of Distal Radial Approach (KODRA)
Recruiting NCT03810599 - Patient-reported Outcomes in the Bergen Early Cardiac Rehabilitation Study N/A
Recruiting NCT06002932 - Comparison of PROVISIONal 1-stent Strategy With DEB Versus Planned 2-stent Strategy in Coronary Bifurcation Lesions. N/A
Not yet recruiting NCT06032572 - Evaluation of the Safety and Effectiveness of the VRS100 System in PCI (ESSENCE) N/A
Recruiting NCT05308719 - Nasal Oxygen Therapy After Cardiac Surgery N/A
Recruiting NCT04242134 - Drug-coating Balloon Angioplasties for True Coronary Bifurcation Lesions N/A
Completed NCT04556994 - Phase 1 Cardiac Rehabilitation With and Without Lower Limb Paddling Effects in Post CABG Patients. N/A
Recruiting NCT05846893 - Drug-Coated Balloon vs. Drug-Eluting Stent for Clinical Outcomes in Patients With Large Coronary Artery Disease N/A
Recruiting NCT06027788 - CTSN Embolic Protection Trial N/A
Recruiting NCT05023629 - STunning After Balloon Occlusion N/A
Completed NCT04941560 - Assessing the Association Between Multi-dimension Facial Characteristics and Coronary Artery Diseases
Completed NCT04006288 - Switching From DAPT to Dual Pathway Inhibition With Low-dose Rivaroxaban in Adjunct to Aspirin in Patients With Coronary Artery Disease Phase 4
Completed NCT01860274 - Meshed Vein Graft Patency Trial - VEST N/A
Recruiting NCT06174090 - The Effect of Video Education on Pain, Anxiety and Knowledge Levels of Coronary Bypass Graft Surgery Patients N/A
Terminated NCT03959072 - Cardiac Cath Lab Staff Radiation Exposure
Completed NCT03968809 - Role of Cardioflux in Predicting Coronary Artery Disease (CAD) Outcomes
Recruiting NCT05065073 - Iso-Osmolar vs. Low-Osmolar Contrast Agents for Optical Coherence Tomography Phase 4
Recruiting NCT04566497 - Assessment of Adverse Outcome in Asymptomatic Patients With Prior Coronary Revascularization Who Have a Systematic Stress Testing Strategy Or a Non-testing Strategy During Long-term Follow-up. N/A
Completed NCT05096442 - Compare the Safety and Efficacy of Genoss® DCB and SeQuent® Please NEO in Korean Patients With Coronary De Novo Lesions N/A