Clinical Trials Logo
  1. Home
  2. Coronary Artery Disease
  3. NCT01281397
  4. Details
NCT01281397 Clinical Trial

Bleeding Prediction in Patients Following Cardiac Surgery Using Whole Blood Aggregometry and Thromboelastometry

Coronary Artery Disease Clinical Trial

Official title:
Bleeding Prediction in Patients Undergoing Cardiac Surgery Using Whole Blood Impedance Aggregometry and Rotational Thromboelastometry

Clinical Trial Details — Status: Terminated

Administrative data
NCT number NCT01281397
Other study ID # Project code: 198-1980976-097
Secondary ID
Status Terminated
Phase N/A
First received January 19, 2011
Last updated December 1, 2014
Start date August 2009
Est. completion date January 2011

Study information
Verified date December 2014
Source University of Zagreb
Contact n/a
Is FDA regulated No
Health authority Croatia: Ministry of Science, Education and Sports
Study type Observational

Clinical Trial Summary

Use of whole blood impedance aggregometry and rotational thromboelastometry can reveal useful data about platelet function and viscoelastic properties of blood clot in patients undergoing cardiac surgery.

The purpose of this study is to clarify whether it is possible to predict patients on excessive risk of perioperative bleeding using whole blood impedance aggregometry and rotational thromoelastometry.

Antiplatelet therapy is the cornerstone in treatment of patients with coronary artery disease. Another research goal is to determine the degree of response to antiplatelet therapy before and after surgery and to investigate whether patients by level of response to antiplatelet therapy before surgery have a higher risk of perioperative bleeding.

Recruitment information / eligibility
Status Terminated
Enrollment 148
Est. completion date January 2011
Est. primary completion date January 2011
Accepts healthy volunteers No
Gender Both
Age group 18 Years and older
Eligibility Inclusion Criteria:

1. > 18 years old

2. Elective cardiac surgery patients

3. Coronary artery disease

4. Aortic valve disease

5. Mitral valve disease

6. Ascendent aorta aneurysm

7. Combine coronary and valve disease

8. Cardiac surgery procedures using cardiopulmonary bypass

Exclusion Criteria:

1. Missing consent

2. Patients with emergent cardiac surgical procedures

3. Patients on antiplatelet therapy other than aspirin or clopidogrel

4. Patients with inaccurate antiplatelet therapy administration documentation

5. Missing data

6. Off-pump procedures

7. Patients younger than 18 years old

8. Patients with severe mental disorders

9. Intrinsic coagulopathy

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Related Conditions & MeSH terms

Locations
Country Name City State
Croatia University hospital center Zagreb- Rebro Zagreb

Sponsors (3)
Lead Sponsor Collaborator
University of Zagreb Clinical Hospital Centre Zagreb, Ministry of Science, Education and Sport, Republic of Croatia

Country where clinical trial is conducted

Croatia, 

Outcome
Type Measure Description Time frame Safety issue
Primary Chest tube output in first 24 hours 24 hours after surgical procedure No
Secondary Allogenic blood products transfusion 7 days after surgery including the day of surgery No
See also
  Status Clinical Trial Phase
Recruiting NCT06030596 - SPECT Myocardial Blood Flow Quantification for Diagnosis of Ischemic Heart Disease Determined by Fraction Flow Reserve
Completed NCT04080700 - Korean Prospective Registry for Evaluating the Safety and Efficacy of Distal Radial Approach (KODRA)
Recruiting NCT03810599 - Patient-reported Outcomes in the Bergen Early Cardiac Rehabilitation Study N/A
Recruiting NCT06002932 - Comparison of PROVISIONal 1-stent Strategy With DEB Versus Planned 2-stent Strategy in Coronary Bifurcation Lesions. N/A
Not yet recruiting NCT06032572 - Evaluation of the Safety and Effectiveness of the VRS100 System in PCI (ESSENCE) N/A
Recruiting NCT04242134 - Drug-coating Balloon Angioplasties for True Coronary Bifurcation Lesions N/A
Recruiting NCT05308719 - Nasal Oxygen Therapy After Cardiac Surgery N/A
Completed NCT04556994 - Phase 1 Cardiac Rehabilitation With and Without Lower Limb Paddling Effects in Post CABG Patients. N/A
Recruiting NCT05846893 - Drug-Coated Balloon vs. Drug-Eluting Stent for Clinical Outcomes in Patients With Large Coronary Artery Disease N/A
Recruiting NCT06027788 - CTSN Embolic Protection Trial N/A
Recruiting NCT05023629 - STunning After Balloon Occlusion N/A
Completed NCT04941560 - Assessing the Association Between Multi-dimension Facial Characteristics and Coronary Artery Diseases
Completed NCT04006288 - Switching From DAPT to Dual Pathway Inhibition With Low-dose Rivaroxaban in Adjunct to Aspirin in Patients With Coronary Artery Disease Phase 4
Completed NCT01860274 - Meshed Vein Graft Patency Trial - VEST N/A
Recruiting NCT06174090 - The Effect of Video Education on Pain, Anxiety and Knowledge Levels of Coronary Bypass Graft Surgery Patients N/A
Terminated NCT03959072 - Cardiac Cath Lab Staff Radiation Exposure
Completed NCT03968809 - Role of Cardioflux in Predicting Coronary Artery Disease (CAD) Outcomes
Recruiting NCT05065073 - Iso-Osmolar vs. Low-Osmolar Contrast Agents for Optical Coherence Tomography Phase 4
Recruiting NCT04566497 - Assessment of Adverse Outcome in Asymptomatic Patients With Prior Coronary Revascularization Who Have a Systematic Stress Testing Strategy Or a Non-testing Strategy During Long-term Follow-up. N/A
Completed NCT05096442 - Compare the Safety and Efficacy of Genoss® DCB and SeQuent® Please NEO in Korean Patients With Coronary De Novo Lesions N/A