Maximal Leg Press Strength Training Study for Coronary Artery Disease Patients

Coronary Artery Disease Clinical Trial

Official title:

Maximal Leg Press Strength Training for Coronary Artery Disease Patients. Training Effect on Serum Testosterone and Work Economy

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT00184457
• Other study ID #: 25060100
• Status: Completed
• Phase: N/A
• First received: September 15, 2005
• Last updated: January 16, 2017
• Start date: September 2005
• Est. completion date: September 2007

Study information

• Verified date: November 2011
• Source: Norwegian University of Science and Technology
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Maximal strength training has been shown to increase muscular strength, muscular volume and work economy. An 8 week maximal leg press training regime will be conducted on cardiac heart failure patients to evaluate whether they increase their maximal leg press strength, work economy, serum testosterone and quality of life. The study hypotheses are that:

1. Aerobic work capacity will increase due to increased work economy, without increases in maximal oxygen uptake.

2. Strength training will increase serum testosterone.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 12
• Est. completion date: September 2007
• Est. primary completion date: April 2007
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 70 Years

Eligibility

Inclusion Criteria:

• Clinically diagnosed coronary artery disease

• Stable coronary artery disease

• 1.5 mm depression in ST segment during a cycling strain test

• Between 18-70 years of age

Exclusion Criteria:

• Unstable coronary artery disease

• Other limitations to exercise than coronary artery disease

• Participants in other study interventions

Related Conditions & MeSH terms

• Coronary Artery Disease
• Coronary Disease
• Heart Failure
• Myocardial Ischemia

Intervention

Behavioral:
• Strength training intervention

Locations

Country	Name	City	State
Norway	Norwegian University of Science and Technology	Trondheim

Sponsors (2)

Lead Sponsor	Collaborator
Norwegian University of Science and Technology	St. Olavs Hospital

Country where clinical trial is conducted

Norway, 

References & Publications (1)

Karlsen T, Helgerud J, Støylen A, Lauritsen N, Hoff J. Maximal strength training restores walking mechanical efficiency in heart patients. Int J Sports Med. 2009 May;30(5):337-42. doi: 10.1055/s-0028-1105946. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Maximal leg press strength
Primary	Work economy
Primary	Serum testosterone
Primary	Quality of life