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Congenital Abnormalities clinical trials

View clinical trials related to Congenital Abnormalities.

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NCT ID: NCT05058001 Not yet recruiting - Clinical trials for Fetal Anomaly of Central Nervous System

Diagnosis Of Neurological Fetal Anomalies

Start date: October 2021
Phase:
Study type: Observational

This is a descriptive cross-sectional study 300 patients coming for antenatal care at sohag governorate undergo mid anatomical scan. Samples 300 pregnant women have mid anatomical scan at 20-22 weeks as routine antenatal care and Examination of the fetal CNS will be performed with a high resolution two dimensional ultrasound machine (Voluson E8) equipped with a RAB 4 to 8MHz multifrequency transabdominal Probe. Four standard recommended views-transventricular, falx, cavum, and posterior fossa or transcerebellar views-provide an overview of fetal intracranial anatomy during the second trimester anatomy scan. Follow-up information will be obtained in all cases, and all infants will be considered healthy by pediatric examination. In selected cases, postnatal single-shot fast spin-echo magnetic resonance (MR) imaging will be performed as integrated, complementary investigation.to confirm diagnosis.

NCT ID: NCT04968483 Not yet recruiting - Spine Deformity Clinical Trials

Perioperative Nutritional Status and Nutritional Support in Patients With Spinal Deformity

Start date: September 1, 2021
Phase:
Study type: Observational

To investigate the nutritional status, nutritional support and postoperative complications of patients undergoing spinal orthopedic surgery during the perioperative period.

NCT ID: NCT04911686 Not yet recruiting - Clinical trials for Flexion Deformity of Knee

Correction of Fixed Knee Flexion Deformity in Children Distraction by Cast Wedge and Rod Lengthening

Start date: June 1, 2021
Phase:
Study type: Observational

The aim of our study is to produce gradual correction of FKFD in younger children.

NCT ID: NCT04897178 Not yet recruiting - Fetal Anomaly Clinical Trials

Machine Learning-based Anomaly Recognition System

MARS
Start date: June 1, 2021
Phase:
Study type: Observational

MARS is an artificial intelligence-powered system that aims at detecting common fetal anomalies during real-time obstetrics ultrasound. The current study comprises 2 stages: (1) The stage of model creation which will include retrospective collection of images from fetal anatomy scans with known diagnoses to train these model and test their diagnostic accuracy. (2) The stage of model validation through prospective application of this model to collected videos with known normal and abnormal diagnoses

NCT ID: NCT04864730 Not yet recruiting - Clinical trials for Anatomic Abnormality

Modal Anatomy of the Ethmoid Bone

AME
Start date: July 15, 2021
Phase:
Study type: Observational

The creation of a 3D model of modal anatomy of the ethmoid could, like other parts of the body, improve anatomical, radiological and perhaps even surgical learning. Anatomical variations might constitute a "background noise" of the modal anatomy, which can be attenuated by multiplying the instances of acquisitions. The objective of this work is to establish modal anatomy of the ethmoid by the analysis of a large number of CT-scan acquisitions carried out in individuals with no acquired sinus pathology.

NCT ID: NCT04686227 Not yet recruiting - Infertility Clinical Trials

Prevalence of Uterine Malformations in Newly Married Unselected Population

Start date: January 2023
Phase:
Study type: Observational

Uterine malformation is occur due to the abnormal development of Mullerian canal during embryogenesis and it is known that it reduces the fertility and live birth rate and also increases the abortion and preterm birth rate. There are different classification methods have been used for defining the uterine malformations. The most common used classification method in the World is American Society of Reproductive Medicine (ASRM)'s system. In addition European Society of Human Reproduction and Embryology (ESHRE) and European Society for Gynaecological Endoscopy (ESGE) developed a new classification system. ASRM Uterine malformation Classification which is used for diagnosis and treatment of uterine malformations in our clinic is subdivided into 7 titles: 1. Agenesis or Hypoplasia -(a. Vaginal b. Cervical c. Fundal d. Tubal e. Combine) 2. Unicornuate -(a. Communicating Horn b. Non-Communicating Horn c. No Cavity d. No Horn) 3. Uterus Didelphus 4. Bicornuate Uterus-(a. Complete b. Partial) 5. Uterine Septum- (a. Complete b. Partial) 6. Arcuate Uterus 7. Diethylstilboestrol (DES) Related The diagnosis of some of the uterine malformations have been done by using two dimensional (2D) ultrasonography, hysterosalphingography or surgically (laparoscopy or laparotomy) traditionally. A non-invasive procedure is required for the diagnosis of the uterine malformation, which is evaluating both the uterine contour and endometrial cavity. In recent years frequently used three dimensional (3D) ultrasound is a non-invasive and quick diagnostic technique, and also it is sensitive as MRI. In hospital based case control studies, the frequency of uterine malformation was generally around 6%, while it was 8% in infertile patients and 12% in patients with abortion. However, there is a lack of prospective studies investigating the prevalence of uterine anomalies, fertility potential and effects on pregnancy outcomes in unselected patient groups in the literature. Therefore, at the high level evidence, there is no evidence that these anomalies affect fertility and pregnancy outcomes and should be corrected. In this study it was aimed to investigate the effects of uterine malformations on fecundability and pregnancy outcomes by evaluating the uterine morphology with 3D ultrasonography and calling for control purposes at the 1st and 2nd years of newly married women between the ages of 18-40.

NCT ID: NCT04627935 Not yet recruiting - Quality of Life Clinical Trials

The Effect of Foot Deformities on Physical Activity, Fatigue Level and Quality of Life in Elderly COPD Patients

Start date: March 1, 2021
Phase:
Study type: Observational

The aim of this study is to investigate the effects of changes in foot structure on physical activity level, fatigue and quality of life in COPD patients.

NCT ID: NCT04610021 Not yet recruiting - Quality of Life Clinical Trials

Prospective i-FactorTM Analysis Fusion Rate and Quality of Life

Start date: March 2021
Phase: N/A
Study type: Interventional

Adult spinal deformity surgery is a complex procedure that involves many risks and complications. Bone grafts and bone substitutes are essential to achieve fusion and manage stability in spinal surgery. Autologous bone has been considered the "gold-standard" for obtaining a spinal fusion. However, the source from which to obtain it is limited. Furthermore, the problems of bone quality in patients with osteoporosis and the morbidity have forced the orthopedic community to seek other options. I-Factor ™ Bone Graft (Cerapedics, Inc., Westminster, CO) is a compound formed by peptide P-15 bound to an anorganic bone mineral of bovine origin that is composed of porous and smooth hydroxyapatite (ABM) particles. In the literature there are no articles which identify bone formation with the i-Factor ™ graft in more than 4 instrumented levels, therefore the development of this study will allow assessing the fusion rate and quality of life of patients, which could lead to an improvement in the management and decision-making of surgical procedures, as well as better control of healthcare spending

NCT ID: NCT04547647 Not yet recruiting - Back Disorder Clinical Trials

Back Deformity in Adolescents Students

Start date: September 2020
Phase:
Study type: Observational

1. Determine the prevalence of scoliosis and kyphosis among male adolescents in preparatory and secondary governmental schools in El Kharga city. 2. To identify factors affecting aetiology and morphology of scoliosis and kyphosis among male adolescents in governmental preparatory and secondary schools in El Kharga city. 3. To assess the effect of scoliosis and kyphosis among male adolescents in governmental preparatory and secondary schools in El Kharga city on related life style aspects.

NCT ID: NCT04527029 Not yet recruiting - Limb Deformity Clinical Trials

Early Intelligent Diagnosis of Limb Deformity in Children by AI and Clinic Application

Start date: December 2022
Phase:
Study type: Observational

The limb deformity in children include congenital limb malformations or acquired from the damage of epiphyseal plate which caused by tumor, inflammation and trauma. Due to the complexity of the disease itself, rapid dynamic development and the characteristics of children's growth and development, the deformities are constantly changing. In addition, the serious lack of clinical diagnosis and treatment resources in the Department of Pediatric Orthopedics has led to the misdiagnosis and improper treatment of children's limb deformities. Thus, its necessary to find an intelligent way to help doctor to early diagnosis of limb deformity and provide a proper treatment in children.