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Congenital Abnormalities clinical trials

View clinical trials related to Congenital Abnormalities.

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NCT ID: NCT06318091 Completed - Clinical trials for Tear Trough Eyelid Deformity

Nanofat Versus Platelet Poor Plasma Gel for Infraorbital Rejuvenation

Start date: June 1, 2021
Phase: Phase 1
Study type: Interventional

this study was conducted for evaluation of the clinical efficacy, safety, and potential side effects of platelet poor plasma gel versus nonfat injection in infraorbital rejuvenation

NCT ID: NCT06257719 Completed - Clinical trials for Lymphatic Malformation

Clinical Characteristics of Lymphatic Malformations

Start date: January 2009
Phase:
Study type: Observational

The primary purpose of this study is to retrospectively identify the clinical characteristics of abdominal lymphatic malformations (ALMs) in our single center in China. The second objective of this study is to retrospectively compare the epidemiological features, clinical presentations, cyst properties, surgical treatments, and risk factors for preoperative complications of ALMs between paediatric participants and adult participants.

NCT ID: NCT06224985 Completed - Tumor Clinical Trials

Computational Anatomy in Surgery for Childhood Tumours and Malformations

IMAG2
Start date: April 16, 2016
Phase:
Study type: Observational

This study is part of the launch of a multidisciplinary project called IMAG2, for image-guided minimally invasive surgery. It involves collaboration between the radiology and surgery teams at Necker Hospital and the Image Processing and Interpretation (TII) team at the LTCI at Télécom ParisTech. To make a decision, surgeons need access to a 3D model reflecting the anatomy of the specific patient and its pathological variations. Patient-specific 3D reconstruction provides a significant improvement, leading to a precise assessment of the malformation or tumour and its relationship with surrounding organs, nerves and vessels. It allows the surgeon to simulate a pre-operative procedure, which is a definite advantage in terms of safe, effective and curative surgery, particularly in oncology. MRI has been chosen as the basic imaging technique because of its non-irradiating nature and the current lack of 3D MRI reconstruction technology. The study aims to provide an aid to diagnosis and surgical planning by developing dedicated methods and algorithms for segmenting not only the tumour but also the main anatomical components surrounding the tumour from 3D MRI imaging data. The imaging will be performed on a 3 Tesla MRI. The data will be that required for diagnosis and surgical planning, acquired on a routine clinical basis with an expected benefit for patients.

NCT ID: NCT06209775 Completed - Clinical trials for Liver Transplantation

Impact of Perioperative Body Composition Abnormalities on Patient Outcomes After Liver Transplantation

Start date: January 1, 2015
Phase:
Study type: Observational

Accumulating evidence suggests the prognostic significance of body composition in chronic diseases and neoplastic diseases. CT imaging-based body composition abnormalities are significantly associated with post-LT adverse outcomes including decreased quality of life (QOL), impaired graft regeneration and mortality. However, the perioperative changes in body composition and their potential clinical implications remain unexplored. The objective of this study is to systematically explore and clarify the correlation between body composition and the prognosis of liver transplant patients through dynamic peri-transplant mornitoring.

NCT ID: NCT06197789 Completed - Clinical trials for Tear Trough Eyelid Deformity

Safety and Efficacy Study of TPX-105 for Correction of Nasojugal Groove

Start date: August 18, 2021
Phase: Phase 3
Study type: Interventional

Nasojugal groove correction is possible through surgical correction procedures, however, due to risks in safety and drawbacks not being able to be done on the young or after surgical procedure, dermal fillers which have the possibility of granulomatous allergic reaction and surface elevation. Therefore, there is a need for a safer procedure for nasojugal groove correction. This study evaluates the safety and efficacy of Autologous human dermal fibroblasts (TPX-105) used for the correction of nasojugal groove. The primary outcome is the improvement of nasojugal groove evaluated by an independent evaluator after administration of TPX-105 at week 24. Secondary outcomes include the improvement of nasojugal groove at week 4 and 12, severity change from baseline at week 4, 12 and 24 evaluated by an independent evaluator, and overall appearance improvement rate rated by subjects using Global Aesthetic Improvement Scale (GAIS) at week 4, 12, 24 and 48.

NCT ID: NCT06163937 Completed - Appetitive Behavior Clinical Trials

Acute Effects of Fruit Juices Consumption on Postprandial Glycemic Responses and Satiety

Start date: September 1, 2023
Phase: N/A
Study type: Interventional

This study investigated the acute effects of two fruit juices on postprandial glycemic responses and satiety in healthy individuals

NCT ID: NCT06151925 Completed - Clinical trials for Labor Onset and Length Abnormalities

Laminaria Tents Versus Vaginal Prostaglandin in Cervical Ripening

Start date: October 1, 2022
Phase: N/A
Study type: Interventional

Mechanical methods used for induction of labor received a great attention nowadays due to the serious side effects of the pharmacological methods. Hygroscopic dilators are considered important subtype of these mechanical methods. One of them is Laminaria which is a synthetic type of sea algae that induces cervical dilation by absorbing water from the cervix and gradually increasing in thickness. The current study will compare the effectiveness and safety of laminiria and vaginal prostaglandins in induction of labor in women with unfavorable cervix.

NCT ID: NCT06031142 Completed - Pregnancy Related Clinical Trials

A Home Telemonitoring System for Wearable Fetal-ECG and EHG Acquisition During Pregnancy

AHTSWFEADP
Start date: May 29, 2023
Phase:
Study type: Observational [Patient Registry]

The goal of this observational is to compare in describing fetal health conditions. The main questions it aims to answer are: - fetal electrocardiogram (fetal heart rate and fetal rhythm) - electrohysterography (uterine contractions). Participants will wear wearable devices and CTG equipment for monitoring for 30 minutes.If there is a comparison group: Researchers will compare clinical CTG equipment to see if this wearable device.

NCT ID: NCT06009601 Completed - Spinal Deformity Clinical Trials

The Relationship Between Pectus Deformities and Spinal Pathologies

Start date: March 9, 2023
Phase:
Study type: Observational

Pectus deformities are common anterior chest wall pathologies. Pectus excavatum is the most common chest deformity with an incidence of 0.1-0.3%. Although the incidence of adolescent idiopathic scoliosis (AIS) is 0.2-3% in the community, some studies show that this rate rises to 17.61-25.58% when it is associated with pectus deformity. While the pectus excavatum rotates the heart to the left with its ribs and cartilages, it pushes the thoracic vertebra to the right side with the internal counterforce created by the heart, which has been shown to push the spine to the right with an asymmetric horizontal force in scoliosis patients with pectus deformity. Based on this, in study, investigators aimed to determine whether there is any relationship between pectus deformities and spinal pathologies, and if there is a relationship, with which pathology it is most common, whether the type of scoliosis seen in pectus deformities with a prominent scoliosis prevalence is a pectus-specific curve, and whether this curve seen in scoliosis is associated with pectus. To determine whether there is a footprint or not.

NCT ID: NCT05900843 Completed - Cerebral Palsy Clinical Trials

Weight Abnormalities With Diet and Exercise Frequency in Egyptian Children With Cerebral Palsy

Start date: November 15, 2022
Phase:
Study type: Observational

The goal of this study was to find prevalence and correlations of different weight abnormalities and risk of abdominal obesity in a random sample of Egyptian children suffering from cerebral palsy. This cross- sectional study hypothesize the prevalence of weight abnormalities and risk of abdominal obesity in addition to positive correlations between weight abnormalities and number of exercise hours and frequency of meals in a random sample of Egyptian children suffering from cerebral palsy RESEARCH QUESTION: 1. What is the prevalence of weight abnormalities and and risk of abdominal obesity in Egyptian children with cerebral palsy? 2. Does the weight abnormalities correlates with number of exercise hours or frequency of meals in children with cerebral palsy?