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Colonoscopy clinical trials

View clinical trials related to Colonoscopy.

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NCT ID: NCT05368792 Not yet recruiting - Colonoscopy Clinical Trials

Prospective Trial Of Osmolar Protocol Solution on Colonoscopy Outcomes and Patient Experience

POOPSCOPE
Start date: May 31, 2022
Phase: N/A
Study type: Interventional

Fasting is the current standard of care for colonoscopies. Recent changes to anesthesia guidelines have allowed for clear fluids to be provided up to 2 hours before procedures, including colonoscopies. This study will compare fasting to a 12.5% carbohydrate solution 2 hours before colonoscopy on patient-reported measures of discomfort, hydration, and colon visibility. The investigators hypothesize that the carbohydrate solution will improve patient-reported measures of discomfort, hydration, and colon visibility.

NCT ID: NCT05366335 Recruiting - Clinical trials for Irritable Bowel Syndrome

Colonoscopic Probiotics Infusion for Functional Gastrointestinal Disease

CPIFGD
Start date: July 4, 2022
Phase: Phase 4
Study type: Interventional

The purpose of this project is to study the the efficacy and safety of probiotics implantation through infusion during colonoscopy in the treatment of functional constipation and irritable bowel syndrome. The study is a single-center, prospective, randomized, single-blind, controlled, cohort study. The invesitigators plan to enroll 80 patients with functional constipation and 80 patients with irritable bowel syndrome. The invesitigators will randomize the included study subjects. The experimental group receive basic treatment and a single infusion of probiotics through colonoscopy. The control group receive basic treatment and a single injection of normal saline through colonoscopy. The invesitigators will follow up the patients for 8-12 weeks. The primary endpoint is the efficacy of the single colonoscopic probiotics infusion in functional constipation and irritable bowel syndrome patients. The secondary endpoint is the safety of the single colonoscopic probiotics infusion in functional constipation and irritable bowel syndrome patients. Other exploratory objectives include the alterations in clinical indicators, fecal microbiota, and intestinal microbiota metabolites in feces and serum.

NCT ID: NCT05336773 Not yet recruiting - Ulcerative Colitis Clinical Trials

Ulcerative Colitis Mayo Score With Artificial Intelligence

Start date: April 2022
Phase:
Study type: Observational

This project will use deep learning to classify colonoscopy images of different severity of ulcerative colitis, so as to assist clinicians in the accurate diagnosis of ulcerative colitis.

NCT ID: NCT05328219 Completed - Colonoscopy Clinical Trials

Effectiveness of Gum Chewing on Polyethylene Glycol Related Intake Adherence, GI Side Effects and Bowel Preparation

Start date: November 1, 2021
Phase: N/A
Study type: Interventional

Problem statement An Experimental Study to assess the effectiveness of Gum Chewing on Polyethylene Glycol (PEG) Related Intake Adherence, GI Side Effects and Bowel Preparation among Patients Undergoing Colonoscopy at ILBS, New Delhi. Objectives of the study The objectives of the study are: Primary objective 1. To compare the effect of gum chewing in experimental vs. control groups in terms of PEG Related Intake Adherence, GI side effects and Bowel Preparation among Patients Undergoing Colonoscopy. Secondary objective 1. To find the relationship of total amount of fluid taken with GI side effects and Bowel Preparation variables in patients undergoing colonoscopy under experimental group. 2. To determine the association of PEG Related Intake Adherence, GI side effects and Bowel Preparation among Patients with socio-demographic and clinical variables in patients undergoing colonoscopy under experimental group.

NCT ID: NCT05323279 Completed - Colonoscopy Clinical Trials

Evaluate the Effects of An AI System on Colonoscopy Quality of Novice Endoscopists

Start date: March 24, 2022
Phase: N/A
Study type: Interventional

In this study, the AI-assisted system EndoAngel has the functions of reminding the ileocecal junction, withdrawal time, withdrawal speed, sliding lens, polyps in the field of vision, etc. These functions can assist novice endoscopists in performing colonoscopy and improve the quality.

NCT ID: NCT05220345 Recruiting - Colonoscopy Clinical Trials

Synergistic Effect of G-Eye Balloon for Behind the Folds Visualization With CADe (Discovery System) on Adenoma Detection Rate.

DiscoveryIII
Start date: March 31, 2022
Phase: N/A
Study type: Interventional

Colonoscopy is the gold standard for colorectal screening. The diagnostic accuracy of colonoscopy highly depends on the quality of inspection of the colon during the procedure. To increase detection new polyp detection systems based on artificial intelligence (AI) have been developed. However, these systems still depend on the ability of the endoscopist to adequately visualize the complete colonic mucosa, especially to detect smaller and more subtle lesions, or lesions hidden behind folds in the colon. With this study we want to combine a device to flatten the folds in the colon combined with an artificial intelligence system to further improve the detection rate of lesions during colonoscopy.

NCT ID: NCT05213741 Not yet recruiting - Colorectal Cancer Clinical Trials

Feasibility Trial of Magnetic-assisted Colonoscope Platform

Start date: May 2024
Phase: N/A
Study type: Interventional

Colorectal cancer (CRC) screening program can reduce colon cancer-related mortality. Current CRC screening methods include stool occult blood and DNA testing, blood based tests and radiologic tests. Colonoscopy is considered the gold standard to detect colorectal neoplasms. Previous studies have estimated that cancer mortality to be 68% to 88% lower among persons who undergo screening colonoscopy than among those who do not. However, colonoscopy is an invasive examination, and 10% to 20% of patients fail to tolerate the procedure; therefore, greatly reduces the success rate of completion of colon examination. External controllability of capsule endoscope by means of an applied magnetic field is a possible solution to the maneuvering problem. However, there is no effective system with straight forward clinical applicability till now. This is ascribable to a lack of reliable magnetic instrumentation suitable for such a purpose. We have reported that magnetic field navigator (MFN) can effectively control the locomotion of capsule endoscope. We have demonstrated the feasibility and safety of magnetic-assisted capsule endoscope for the examination of upper gastrointestinal tract. In this study, we develop a magnetic-assisted capsule colonoscope by combination of the integrated circuit complementary metal-oxide-semiconductor imaging sensor, light-emitting diode, and magnetic control technology. This magnetic-assisted capsule colonoscope operation system includes a MFN Platform, high-end hand-controlled joystick, combined circuit component, control interface and software. This magnetic-assisted capsule colonoscope operation system creates a friendly operating environment for the operators, and may establishe a novel screening system for the colon.

NCT ID: NCT05163236 Completed - Colonoscopy Clinical Trials

Sensitivity of Fecal Immunochemical Test (FIT) for Colorectal Cancer (CRC) Screening

FITBACK
Start date: April 20, 2021
Phase:
Study type: Observational

Fecal immunochemical test (FIT) was introduced in France late 2015, FIT has better diagnostic accuracy for colorectal cancers (CRCs) than previous screening tests. Our primary objective was to evaluate the sensitivity of FIT and the proportion of interval cancer.

NCT ID: NCT05125939 Recruiting - Colonoscopy Clinical Trials

Can Overall Adenoma Detection Rate Replace Screening Adenoma Detection Rate ? Multicenter Study

Start date: November 20, 2021
Phase:
Study type: Observational

This is a prospective equivalence colonoscopy study evaluating whether overall adenoma detection rate (ADR) is a reliable alternate for screening ADR. Overall indication includes screening, surveillance, and diagnostic indications.

NCT ID: NCT05089071 Completed - Colonoscopy Clinical Trials

Effect of Two Colonoscopy AI Systems for Colon Polyp Detection

Start date: November 1, 2021
Phase: N/A
Study type: Interventional

Computer-aided detection (CADe) systems have been actively researched for polyp detection in colonoscopy. The investigators aim to identify the effect of two CADe systems according to the system performance on false positive rate