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Colonoscopy clinical trials

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NCT ID: NCT06317350 Recruiting - Colonoscopy Clinical Trials

Clinical Study to Evaluate the Efficacy and Safety of GNS-212-E in Bowel Preparation for Colonoscopy

GNS-212-E
Start date: March 11, 2024
Phase: Phase 3
Study type: Interventional

This is a prospective, randomized, single-blind, parallel, active-controlled, and multi-center Phase III clinical trial.

NCT ID: NCT06279481 Recruiting - Pain Clinical Trials

Effect of Virtual Reality (VR) on Pain Relieve During Colonoscopy

Start date: March 2024
Phase: N/A
Study type: Interventional

Purpose: To evaluate the effectiveness and safety of virtual reality (VR) technology in alleviating pain during colonoscopy. Design and Methods: In the context of a single-centered, prospective, randomized controlled study, the pain levels experienced during colonoscopy are compared between the VR group and the control group.

NCT ID: NCT06223347 Recruiting - Clinical trials for Inflammatory Bowel Diseases

Improved and Simplified Staining Technique for Dysplasia Detection in Colitis

IST-DDC
Start date: January 2024
Phase:
Study type: Observational

Comparing chromoendoscopy to a digital staining technique and White light in patients with IBD attending scheduled surveillance colonoscopy

NCT ID: NCT06173258 Recruiting - Colonoscopy Clinical Trials

Water Exchange Colonoscopy With Artificial Intelligence-assisted Detection

Start date: December 18, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to compare the detected adenoma per colonoscopy (APC) in participants undergoing screening, surveillance, and positive fecal immunochemical test (FIT) or guaiac fecal occult blood test (gFOBT). There will be two arms in this study: WE water control and water plus artificial intelligence (AI). The main question it aims to answer is whether the addition of AI into water exchange (WE) colonoscopy increases APC than WE alone. The control method will use water instead of air inserted into the colon. The study method will use a commercially available AI system plus water during the procedure. Researchers will compare APCs to see if the addition of AI increases detection of adenomas during WE colonoscopy.

NCT ID: NCT06111937 Recruiting - Colonoscopy Clinical Trials

Time Interval After Gastric Emptying and Quality of Bowel Cleansing

Start date: June 1, 2023
Phase: N/A
Study type: Interventional

The goal of this [clinical trial] is to [explore the balance time point between the waiting time for intestinal preparation after gastric emptying and quality of bowel preparation.] in [patients with painless colonoscopy]. The main question[s] it aims to answer are: [whether the gastric is empty or not 2 hours after finishing drinking 1.5 L of MgSO4 solution within 2 hours] [whether the quality of patients' bowel preparation is superior in a time period of 2-4 hours after finishing drinking 1.5 L of MgSO4 solution] Participants will [ be asked finishing the last dose of 1.5 L MgSO4 solution within 2 hours and received ultrasound gastric assessment immediately 2 or 4 hours after finishing drinking MgSO4 solution in a 15 minutes time interval until the gastric is empty. As soon as the gastric is empty, patients receive painless colonoscopy within 2 hours or 2-4 hours. Researchers will compare [patients receiving painless colonoscopy within 2 hours or 2-4 hours after finishing drinking 1.5 L of MgSO4 solution] to see if [the quality of patients' bowel preparation is superior in a time period of within 2 hours].

NCT ID: NCT06051955 Recruiting - Colonoscopy Clinical Trials

Evaluation of an Oral Sodium Sulfate Solution for Patients With Prior Difficult or Incomplete Cleansing

OSS
Start date: October 11, 2023
Phase: N/A
Study type: Interventional

This case series aims to evaluate the effectiveness and tolerability of Oral Sulfate Solution (OSS) in patients who had previously experienced poor colonoscopy preparation.

NCT ID: NCT06007313 Recruiting - Colonoscopy Clinical Trials

Mental Stress and Bowel Preparation Quality

Start date: May 1, 2023
Phase:
Study type: Observational

The goal of this cross-sectional study was to explore the relationship between physical and psychological stress and the quality of bowel preparation before a colonoscopy examination, in order to improve the quality of bowel preparation. The main questions it aims to answer are: Does physical and psychological stress affect the quality of colonoscopic bowel preparation, and delay disease detection? How can we improve the quality of colonoscopy? Participants will be asked to complete a questionnaire containing their demographics, history of diseases and drugs, lifestyle habits, and physical and 14-item perceived stress scale(PSS-14). Quality of bowel preparation was assessed by the Boston bowel preparation scale(BPS).

NCT ID: NCT05797207 Recruiting - Clinical trials for Inflammatory Bowel Diseases

Evaluation of the Diagnostic Potential of Artificial Intelligence-assisted Fecal Microbiome Testing for Inflammatory Bowel Disease

Start date: April 10, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to evaluate the diagnostic potential of Artificial Intelligence-assisted Fecal Microbiome Testing for the diagnosis of inflammatory bowel disease. The main question it aims to answer is: • Is Artificial Intelligence-assisted Fecal Microbiome Testing a reliable screening test for inflammatory bowel disease? Participants will be asked to provide fecal samples to be analyzed with next-generation sequencing techniques. If there is a comparison group: Researchers will compare the diagnostic performance of AI-assisted Fecal Microbiome Testing with colonoscopy to see the correlation between the results of both interventions.

NCT ID: NCT05795725 Recruiting - Colon Cancer Clinical Trials

Evaluation of the Diagnostic Potential of Artificial Intelligence-assisted Fecal Microbiome Testing for Colon Cancer

Start date: May 1, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to evaluate the diagnostic potential of Artificial Intelligence-assisted Fecal Microbiome Testing for the diagnosis of colon cancer. The main question it aims to answer is: • Is Artificial Intelligence-assisted Fecal Microbiome Testing a reliable screening test for colon cancer? Participants will be asked to provide fecal samples to be analyzed with next-generation sequencing techniques. If there is a comparison group: Researchers will compare the diagnostic performance of AI-assisted Fecal Microbiome Testing with colonoscopy to see the correlation between the results of both interventions.

NCT ID: NCT05584423 Recruiting - Colonoscopy Clinical Trials

The Correlation Between the Difficulty of Colonoscopy and the Patient's Personality

Start date: August 15, 2023
Phase:
Study type: Observational

The goal of this observational study is to explore the correlation between the difficulty of colonoscopy and the patients' personality in the population receiving initial colonoscopy in Peking Union Medical College Hospital. The main question it aims to answer is: Whether the difficulty of colonoscopy is related to any personality score of big five personality dimensions Participants will: 1. Receive routine colonoscopy 2. Fill out the GAD-7 and PHQ-9 scales 3. Fill out the Big Five Personality Questionnaire.