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Chronic Pain clinical trials

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NCT ID: NCT05125978 Withdrawn - Pain, Chronic Clinical Trials

Efficacy and Safety of Canadá Association in the Treatment of Chronic Pain

CANADÁ
Start date: September 2026
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of Canadá association in the treatment of chronic pain

NCT ID: NCT05097729 Withdrawn - Chronic Pain Clinical Trials

rTMS for Relieving Chronic OA Pain

Start date: November 15, 2021
Phase: N/A
Study type: Interventional

In this study the investigators aim to examine the effects of Transcranial Magnetic Stimulation (TMS) on hippocampal network connectivity and pain levels in individuals with pain due to knee osteoarthritis.

NCT ID: NCT04609787 Withdrawn - Chronic Pain Clinical Trials

Immersive Virtual Reality and Central Sensitization in People With Chronic Pain

Start date: January 5, 2021
Phase: N/A
Study type: Interventional

Patients with chronic low back pain from Dr. Robert Edwards' study at the Brigham & Women's Pain Institute that examines sensory and pain perceptions in patients with chronic pain who use opioids will complete quantitative sensory testing (QST) and current pain levels will be obtained. Subsequently, 20-minutes of Immersive Virtual Reality (IVR) will be completed and then QST testing will be completed again post-IVR.

NCT ID: NCT04464512 Withdrawn - Chronic Pain Clinical Trials

Suboxone User Perioperative Early Referral and Enhanced Recovery After Surgery- Orthopaedic Trauma Surgery Population

SUPER-ERAS
Start date: January 10, 2020
Phase: Phase 4
Study type: Interventional

This is a randomized controlled trial. Patients will be randomly assigned to either the control or treatment group, with equal allocation using block randomization. The primary null hypothesis is that a combination sufentanil and buprenorphine based pain control regimen will not result in lower morphine equivalent requirements for pain control when compared to a classic fentanyl and hydromorphone based regimen. The secondary working hypothesis is that the patient satisfaction survey mean satisfaction scores will be higher in the buprenorphine and sufentanil treated group when compared to the classic fentanyl and hydropmorphone treated group. The secondary null hypothesis is that the patient satisfaction surveys mean scores will not be significantly different in the buprenorphine and sufentanil treated group when compared to the classic fentanyl and hydropmorphone treated group. The tertiary working hypothesis is that the patients will have significantly lower rates of relapse as defined by follow up with their home suboxone clinic at 2 and 4 weeks. The tertiary null hypothesis is that patients have equivalent rates of relapse as defined by follow up with their home suboxone clinic at 2 and 4 weeks.

NCT ID: NCT04381975 Withdrawn - Chronic Pain Clinical Trials

Move in Mind: Program for Reducing Musculoskeletal Pain

Start date: January 1, 2024
Phase: N/A
Study type: Interventional

The present pilot study will explore the range of mental and physical health benefits associated with a Rolfing®-based intervention program ("Move in Mind"). To assess the effects of this program on pain management and various psychological outcomes, the investigator's study will be offered to individuals with mild chronic musculoskeletal pain (e.g., lower back pain, neck pain, shoulder pain, knee pain, arthritic pain). Shortened from ten to six sessions and adapted to a group setting by Rolfing® instructor Monica Canducci, the intervention will be delivered weekly by Ms. Canducci, who is certified in Rolfing®. The program will target the potential associations of the Move in Mind program with better pain management (primary outcome) as well as increased body awareness and presence, increased well-being, and better stress management (secondary outcomes). Interested participants will be asked to complete a battery of questionnaires and psychometric scales to assess the variables of interest before (baseline) and after their participation in the Move in Mind program (six-week follow-up). A waitlist control group will also be assessed at baseline and follow-up and will then receive the Move in Mind sessions subsequently and also assessed after their participation.

NCT ID: NCT04290845 Withdrawn - Depression Clinical Trials

A Behavioral Intervention for Depression and Chronic Pain in Primary Care (Relief-Hybrid)

Start date: February 2023
Phase: N/A
Study type: Interventional

Chronic pain and depression frequently co-exist in late and mid-life and contribute to increased disability, high health care costs, psychiatric comorbidity, and suicide. Older and middle-aged depressed-pain patients: a) are mainly treated in primary care practices; and b) are often prescribed medication, which increases the risk for addiction to opioids and benzodiazepines. Despite the need and desire by the patients and providers for primary care behavioral intervention, behavioral interventions are scarce in primary care. To address this need, Relief-Hybrid was created. Subjects are randomized to either the Relief-Hybrid intervention or to Referral to Mental Health/Usual Care. Subjects in both arms will complete research assessments at 6, 9, and 12 weeks. Subjects in the Relief-Hybrid arm will receive 5 weekly sessions with the study therapist (licensed social workers, LCSWs) and 4 self-administered, mobile technology-assisted sessions.

NCT ID: NCT04287452 Withdrawn - Chronic Pain Clinical Trials

Canine-Assisted ANxiety Reduction IN Emergency Care IV

CANINE IV
Start date: March 1, 2022
Phase: N/A
Study type: Interventional

Prior literature demonstrates that human stress can be reduced with exposure to animals. This study challenges current dogma by introducing a widely available, low cost method of dog therapy to reduce patient and provider stress. The objectives of this study are to determine if interaction with a certified therapy dog and handler can; - decrease reported anxiety levels in emergency department (ED) patients, - decrease salivary cortisol in ED patients, - decrease total morphine equivalent dosing in the emergency department or at discharge and/or, - decrease reported stress levels in emergency department providers caring for participating patients when compared to usual care.

NCT ID: NCT04250662 Withdrawn - Chronic Pain Clinical Trials

Study of the Acute Effects of Guided Imagery and tDCS on Pain Levels in Women With Chronic Pelvic Pain

Start date: February 2020
Phase: N/A
Study type: Interventional

This is a single blind, randomized, exploratory study of transcranial direct stimulation (tDCS) intervention or sham tDCS administered with a standardized guided imagery intervention for chronic pelvic pain. Transcranial Direct Current Sstimulation (tDCS) is a non-invasive brain stimulation therapy. Guided Imagery is a form of hypnosis used to create relaxation.Up to 25 adult women with chronic pelvic pain will be enrolled and randomized (like a flip of a coin). Subjects will remain blinded throughout the study. Subjects will be randomized into one of the following four arms: active tDCS with guided imagery, active tDCS alone (without guided imagery), sham tDCS with guided imagery, or sham tDCS alone (without guided imagery).

NCT ID: NCT04235218 Withdrawn - Clinical trials for Chronic Pain Syndrome

Brief-Illness Perception Questionnaire (Brief-IPQ) Used in Patients With Chronic Non-malignant Pain.

Start date: May 20, 2022
Phase:
Study type: Observational

We wish to clarify whether we can demonstrate a correlation between scores in Brief-IPQ and the effect of treatment in patients referred to our department, Interdisciplinary Pain Center Zealand University Hospital Koege, Denmark. The purpose is to outline whether we can use Brief-IPQ with Chronic Pain disorders and thereby detect those of our referred patients who are at risk for poor treatment response in an early state. In these cases, we can offer psychological intervention at the beginning of the course of treatment, in order to optimize the conditions for patients and achieve an optimal treatment effect.

NCT ID: NCT04155268 Withdrawn - Healthy Clinical Trials

Flotation-REST for Chronic Pain, Stress, and Sleep

Start date: March 9, 2020
Phase: N/A
Study type: Interventional

This randomized crossover trial aims to examine the effects of Flotation-REST (Reduced, Environmental, Stimulation, Technique/Therapy) compared to laying in a dark room (with reduced environmental stimulation) for those with chronic musculoskeletal pain. This design will allow for comparisons between the two interventions on daily diary assessments of pain, stress, and sleep, both between groups and within individuals.