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Cardiac Event clinical trials

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NCT ID: NCT05774587 Recruiting - Cardiac Event Clinical Trials

Mobile Health for Cardiac Rehabilitation (Motivate-CR+)

Start date: July 6, 2023
Phase: N/A
Study type: Interventional

The investigators aim to conduct a feasibility study to evaluate a model where mobile health (mHealth) technology supports a remote home-based PA and counselling intervention immediately post hospital discharge to increase uptake to cardiac rehabilitation. Our overall objective is to test the feasibility of an evidence-based complex intervention prior to evaluation in a future randomized control trial (RCT)

NCT ID: NCT05602298 Recruiting - Surgery Clinical Trials

The Quality of Recovery-15 Survey After Cardiac Surgery

Start date: August 4, 2022
Phase:
Study type: Observational

Patient reported outcomes are becoming increasingly recognized as an important metric to determine efficacy of interventions following recovery after cardiac surgery. Quality of Recovery 15 survey is a tool that attempts to measure patients' recovery across several different domains (i.e physical, emotional and social). This tool has been validated extensively in the post operative patient population, but these studies contained only small numbers of cardiac surgery patients. This population faces unique challenges to recovery such as a longer duration of mechanical ventilation, ICU and hospital LOS, delirium, significant pain in the first 24-48 hours and post operative arrhythmias. This study aims to validate the QoR 15 in this population exclusively to determine if it is feasible, valid, reliable and responsive in this unique population.

NCT ID: NCT05443321 Recruiting - Asthma Clinical Trials

Advancing Health Information Exchange (HIE) During Inter-hospital Transfer (IHT) to Improve Patient Outcomes

Start date: November 1, 2022
Phase: N/A
Study type: Interventional

Sub-optimal transfer of clinical information during inter-hospital transfer (IHT, the transfer of patients between acute care hospitals) is common and can lead to patient harm. To address this problem, the investigators will use key stakeholder input to refine and implement an interoperable health information exchange platform that integrates with the electronic health record and improves the reliability of and access to necessary clinical information in three use cases involving transfer of patients between sending and receiving hospitals with varying levels of affiliation and health record integration. The investigators will assess the effect of this intervention on frequency of medical errors, evaluate the use and usability of this platform from the perspective of those that interact with it, and use these results to develop a dissemination plan to spread implementation and use of this platform across other similar institutions.

NCT ID: NCT05288894 Recruiting - Cardiac Arrhythmia Clinical Trials

Repaired Tetralogy of Fallot Italian Registry

RETE-Fallot
Start date: March 1, 2021
Phase:
Study type: Observational [Patient Registry]

The CMR/CT WG of the Italian pediatric cardiology society set up a multi-center observational clinical database of repaired-TOF evaluated. This registry will enroll prospectively patients evaluated by CMR for clinical indication in most of the CHD Italian centers. Data collection will include surgical history, clinical data, imaging data, and also adverse cardiac events for a period of 6 years.

NCT ID: NCT05200078 Recruiting - Breast Cancer Clinical Trials

Deep Inspiration Breath-hold Radiotherapy for Left-sided Breast Cancer

Start date: September 1, 2021
Phase:
Study type: Observational

Postoperative breast radiotherapy (RT) has been associated with increased risk of heart toxicity. However, there is a lack of knowledge for radiation-induced early cardiovascular injury, especially for hypofractionated RT. This study aims to prospectively detect and predict early clinical or subclinical cardiac events in women undergoing adjuvant RT for breast cancer.

NCT ID: NCT05040750 Recruiting - Cardiac Event Clinical Trials

Correlation Between Cardiac Markers and Severity of COVID-19

Start date: September 1, 2021
Phase:
Study type: Observational

By July 9, 2020, the global pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection had resulted in over 11.8 million confirmed cases and over 545000 deaths. Patients with a history of cardiovascular disease are especially vulnerable and have a bad prognosis. According to the findings, cardiac injury manifested by cardiac biomarker elevation is detected in a significant number of COVID-19 patients and is linked to poor outcomes and mortality. However, it is unclear how effective cardiac biomarkers are in COVID-19 prognosis and how to use these indicators.

NCT ID: NCT04573049 Recruiting - Heart Failure Clinical Trials

The Effectiveness and Safety of Levosimendan in Patients With Severe Aortic Stenosis and Heart Failure Undergoing Transcatheter Aortic Valve Replacement

Start date: September 1, 2020
Phase: Phase 4
Study type: Interventional

A study to evaluate the effectiveness and safety of levosimendan compared with placebo in subjects with severe aortic stenosis and heart failure undergoing transcatheter aortic valve replacement

NCT ID: NCT04201119 Recruiting - Surgery Clinical Trials

Effect of Oxiris® Membrane on Microcirculation Following Cardiac Surgery Under Cardiopulmonary Bypass: a Pilot Prospective Monocentric Study (Oxicard Study).

OXICARD
Start date: February 28, 2020
Phase: N/A
Study type: Interventional

Oxiris membrane is an efficient tool for inflammatory cytokines adsorption. Cardiac surgery is followed by an inflammatory state mimicking sepsis. The investigators hypothesized that cytokine adsorption by Oxiris® membrane can attenuate the inflammatory response and thus decrease the microcirculation impairment that followed cardiac surgery.

NCT ID: NCT03932604 Recruiting - Atrial Fibrillation Clinical Trials

Atrial Sensing Capability for Better Detection of Atrial Fibrillation

Start date: June 1, 2019
Phase: N/A
Study type: Interventional

This prospective multi-center randomized controlled study aims to compare atrial fibrillation detection and inappropriate therapy according to activation of atrial sensing capability in patients with implantable cardioverter defibrillator.

NCT ID: NCT03785704 Recruiting - Breast Neoplasms Clinical Trials

Clinical Study of Xinmailong Injection on Reducing Cardiovascular Toxicity in Adjuvant Chemotherapy in Breast Cancer

Start date: January 1, 2019
Phase: Phase 2
Study type: Interventional

Totally 60 subjects will be included in the study. The present study was aimed to observe and evaluate the effect of Xinmailong injection on reducing cardiovascular toxicity associated with adjuvant chemotherapy after breast cancer surgery. The primary endpoint was 6 months of cardiac safety. Secondary endpoints included 3 months of cardiac safety, adverse events (AE), severe adverse events (SAE), and DFS.