Breast Cancer Clinical Trial
Official title:
Deep Inspiration Breath-hold Radiotherapy for Left-sided Breast Cancer in Reducing Early Cardiac Injury: a Phase II Prospective Study
Postoperative breast radiotherapy (RT) has been associated with increased risk of heart toxicity. However, there is a lack of knowledge for radiation-induced early cardiovascular injury, especially for hypofractionated RT. This study aims to prospectively detect and predict early clinical or subclinical cardiac events in women undergoing adjuvant RT for breast cancer.
Women with left-sided breast cancer undergo hypofractionated RT at either free-breathing or deep inspiration breath-hold. The incidence and potential clinical, dosimetric and biological indicators of early clinical or subclinical cardiac injury are investigate at 2 years. ;
| NCT number | NCT05200078 |
| Study type | Observational |
| Source | Chinese Academy of Medical Sciences |
| Contact | Shu-Lian Wang |
| Phone | 86-13366191993 |
| [email protected] | |
| Status | Recruiting |
| Phase | |
| Start date | September 1, 2021 |
| Completion date | June 30, 2023 |
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