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Body Weight Changes clinical trials

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NCT ID: NCT03348566 Completed - Obesity Clinical Trials

Fish and Marine Fatty Acids, Genetic Signatures of Diet Adaptation, and Long-term Weight Changes

Start date: February 1, 2015
Phase:
Study type: Observational

the investigators tested whether genetic variants near FADS cluster, which were recently identified to be signatures of adaptation to fish- and n-3 PUFAs-rich diet, interacted with these dietary factors on long-term change of body mass index (BMI).

NCT ID: NCT03321331 Completed - Clinical trials for Overweight and Obesity

A Self-directed Mobile Intervention to Promote Weight Control Among Employees of a Lebanese University

WaznApp
Start date: March 5, 2018
Phase: N/A
Study type: Interventional

WaznApp study is a 12-week randomized controlled trial aimed to evaluate the feasibility and preliminary efficacy of a self-directed behavioral weight-loss intervention targeting employees of an academic institution, using two popular consumer mobile applications for weight loss. The hypothesis is that individuals assigned to the app that provides interactive feedback and proactively motivates engagement in healthy behaviors (eating healthily and being more active) will be significantly better than those who receive the comparison condition (a simple calorie tracking app).

NCT ID: NCT03283657 Completed - Clinical trials for Diabetes Mellitus, Type 2

Diabetes Risk Education and Communication Trial

DiRECT
Start date: November 1, 2017
Phase: N/A
Study type: Interventional

A large body of research has demonstrated that intensive lifestyle interventions and metformin are effective treatments to prevent or delay diabetes among high-risk adults, yet neither treatment is routinely used in practice. This pilot study will develop and evaluate the Diabetes Risk Education and Communication Trial (DiRECT) intervention, which communicates information about diabetes risk and treatment options for preventing diabetes among primary care patients with prediabetes. Given that 38% of U.S. adults have prediabetes, this project has large potential to impact public health by developing a scalable intervention to promote the use of evidence-based treatments that lower diabetes risk in this population.

NCT ID: NCT03235440 Completed - Quality of Life Clinical Trials

Feasibility of the Camp Power Up Program on Children's Body Weight and Quality of Life

CampPowerUp
Start date: June 19, 2017
Phase: N/A
Study type: Interventional

This study will evaluate the effects of a one week weight management summer camp on children's weight, quality of life, mood and feelings, self-esteem, weight management efficacy, enjoyment of physical activity, and body image.

NCT ID: NCT03204396 Completed - Smoking Cessation Clinical Trials

Smoking Cessation Facilitated by Glucagon-like Peptide-1 (GLP-1) Analogues

SKIP
Start date: June 26, 2017
Phase: Phase 2
Study type: Interventional

Cigarette smoking is the leading preventable cause of premature death worldwide. However smoking is a very difficult addiction to break whereby main reasons for not quitting or relapsing after cessation are the nicotine withdrawal syndrome and post-cessational weight gain. GLP-1 analogues are well known to stimulate insulin secretion and to reduce energy intake and therefore body weight. Recent findings from animal and human studies suggest a role of GLP-1 in the pathophysiology of addiction. The putative role of GLP-1 analogues in nicotine reward regulation combined with its weight reducing effects might be of major interest in view of novel pharmacotherapeutic options for smoking cessation. - Substudy "fMRI": This substudy is to evaluate effects of Dulaglutide treatment on functional neuronal changes in smokers who want to quit smoking. - Substudy "Energy": This substudy is to investigate the effect of Dulaglutide (Trulicity®) on REE and further parameters associated with energy metabolism (bodycomposition, haemodynamic parameters and catecholamine action) in a subset of patients recruited for the main trial.

NCT ID: NCT03202420 Completed - Obesity Clinical Trials

Study to Test the Feasibility, Acceptability, and Weight Change of Take Off Pounds Sensibly (TOPS) in a Safety Net Clinic

TOPS at DOC
Start date: December 22, 2017
Phase: N/A
Study type: Interventional

The purpose of this pilot proposal are the following: 1) to determine the feasibility and acceptability of integrating the TOPS weight loss program into underserved populations through an urban safety net clinic and 2) to gather preliminary data of weight change to inform the design of a future randomized, controlled trial to determine the efficacy of the TOPS program in safety net clinics. To achieve these goals, the investigators will pursue the following Specific Aims: Specific Aim 1. Assess the feasibility and acceptability of integrating the TOPS program into an urban safety net clinic, with process measures (i.e., recruitment/refusal rates and retention/dropout rates) and focus groups. Hypothesis 1. Integrating the TOPS program into an urban safety net clinic is feasible and acceptable to participants. Specific Aim 2. Assess the percent of participants in the TOPS intervention arm with clinically significant weight change (i.e., weight loss of ≥5% of initial body weight) at 12, 26, and 52 weeks. Hypothesis 2. 10%, 25%, and 33% of participants in the TOPS intervention arm will lose ≥5% of initial body weight at 12, 26, and 52 weeks, respectively.

NCT ID: NCT03196453 Not yet recruiting - Overweight Clinical Trials

Fit Child - Clinical Study on Weight Control

FITCHI
Start date: August 1, 2017
Phase: N/A
Study type: Interventional

Children with abnormal weight development of BMI will be given either placebo or a probiotic protein formula and measures of weigh gain during a 3-mont treatment will be conducted

NCT ID: NCT03156660 Completed - Smoking Cessation Clinical Trials

Efficacy of Two Novel Behavioral Post-cessation Weight Gain Interventions

Start date: November 30, 2017
Phase: N/A
Study type: Interventional

The study aims to randomize 400 participants to 1 of 3 arms: a) a weight stability intervention prior to smoking cessation (Group 1); b) a weight loss intervention prior to smoking cessation (Group 2); or c) a self-guided weight management prior to cessation (Group 3) and to determine the efficacy of the interventions on preventing weight gain at 12 month follow-up. All 3 conditions receive a highly efficacious behavioral smoking cessation program and 6 months of varenicline pharmacotherapy (ChantixTM), the most efficacious medication for smoking cessation.

NCT ID: NCT03146429 Completed - Weight Change, Body Clinical Trials

Prediction of Future Weight Change With Dopamine Transporter

Start date: January 1, 2017
Phase:
Study type: Observational

This is the re-analyzing study of observational study by Parkinson's Progression Markers Initiative

NCT ID: NCT03118882 Completed - Breast Cancer Clinical Trials

STI.VI. Study: How to Improve Lifestyles in Screening Contexts

STIVI
Start date: May 2010
Phase: N/A
Study type: Interventional

The main study objective is to determine the feasibility and impact (effectiveness) of intervention models for lifestyle changing (diet and physical activity) on health outcomes. Women 50 to 54-year-old attending the local breast cancer screening and 58-year-old people (both sexes) undergoing colorectal cancer screening are invited to participate in the study. Compliers are randomized into 3 intervention groups (Diet, Physical Activity, and Physical Activity and Diet) and into the 'usual care' Control group. Biological sampling (blood and saliva) is collected from all participants. All participants undergo also anthropometric measurements and fill in a self-administered validated questionnaire on their dietary and physical activity habits. All enrolled subjects receive a booklet with basic information about diet and physical activity. Subjects randomized to the 3 intervention groups are also offered one theoretical and three training courses. The courses are specifically designed for the different interventions proposed and aimed at reinforcing the educational counseling and at supporting behavioral changes. Follow-up is performed at 8 (intermediate follow-up) and 12-14 (final follow-up) months for repeating anthropometric measurements and questionnaire filling and blood sampling (at the final one).