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Optical Coherence Tomography in Acute Coronary Syndrome — OPTICO-ACS  

Acute Coronary Syndrome Clinical Trial

Official title:
Optical Coherence Tomography in Acute Coronary Syndrome

Clinical Trial Summary

The OPTICO-ACS- study program - combining for the first time in vivo characterization of the ACS-causing "culprit lesion" by intracoronary imaging technique with optical coherence tomography (OCT) and molecular analysis of immune-cells derived from the culprit coronary thrombus and biochemical analyses in patients with acute-coronary-syndrome (ACS).

Clinical Trial Description

Using a translational scientific approach the study aims to (a) get a better insight into the different pathophysiological processes in both clinical settings - plaque rupture (RFC) and plaque-erosion (IFC) with focus on to the inflammatory process and molecular mechanisms (b) identify special signatures including clinical and biochemical markers as biomarkers subject to different culprit plaques types and (c) to test its prognostic implications in patients after ACS. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03129503
Study type Observational [Patient Registry]
Source Charite University, Berlin, Germany
Contact
Status Active, not recruiting
Phase
Start date April 28, 2017
Completion date March 31, 2024
View Details
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