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Apnea clinical trials

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NCT ID: NCT06256640 Recruiting - Pregnancy Related Clinical Trials

Mandibular Advancement Device (MAD) in Pregnant Women With Obstructive Sleep Apnea (OSA)

OBMAD
Start date: February 1, 2024
Phase: N/A
Study type: Interventional

We propose a single-arm trial to test the patient uptake and preliminary efficacy of MAD in a sample of 10 pregnant women with mild-to-moderate OSA. Study outcomes include patient-reported symptoms and objectively assessed sleep parameters assessed before treatment, during and after 10 weeks of MAD intervention (during pregnancy) and postpartum.

NCT ID: NCT06249490 Recruiting - Clinical trials for Obstructive Sleep Apnea

Stellate Ganglion Block in Obstructive Sleep Apnea

Start date: February 29, 2024
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to test the efficacy of stellate ganglion block in Obstructive Sleep Apnea. The main question it aims to answer are: • Can stellate ganglion block improve Obstructive Sleep Apnea? Patients were randomly divided into two groups, all provided with routine therapy. Based on this, the experimental group was given stellate ganglion block. The video fluoroscopic swallowing study was done to test the swallowing function before and after the study.

NCT ID: NCT06247878 Recruiting - Clinical trials for Obstructive Sleep Apnea

Skiin-PSG Sleep Apnea

Start date: February 1, 2024
Phase:
Study type: Observational

The goal of this observational study is to develop new algorithms to detect apnea and/or hypopnea to provide additional insights to Skiin users and to their circle of care to validate and/or improve the current algorithms of the Skiin system for extraction of biological metrics during sleep based on the Skiin ECG and accelerometry data.

NCT ID: NCT06239883 Recruiting - Clinical trials for Obstructive Sleep Apnea

This Research Project Studies the Relationship Between OSA and Nocturia.

Start date: June 1, 2019
Phase:
Study type: Observational

The main goal of the study is to explore the relationship between obstructive sleep apnoea and nocturia.

NCT ID: NCT06195878 Recruiting - Clinical trials for Spinal Cord Injuries

Sleep Apnea in Paralympic Ontario-Resident aThletes With Spinal Cord Injury (SPORTS) Study

Start date: February 20, 2024
Phase: N/A
Study type: Interventional

This single arm clinical trial will assess whether continuous positive airway pressure (CPAP) therapy in the management of moderate-to-severe sleep-related breathing disorders (SRBDs) among para-athletes living with cervical/thoracic, complete or incomplete spinal cord injury (SCI) is effective in improving cognitive impairment, in reducing fatigue, depression, anxiety, and overall quality of life. Further, the study will evaluate the effectiveness of CPAP therapy in improving their performance in sports and the perceived risk of injuries.

NCT ID: NCT06189755 Recruiting - Clinical trials for Obstructive Sleep Apnea

MicroRNAs as Biomarkers for Obstructive Sleep Apnea

MIR-OSA
Start date: April 1, 2024
Phase:
Study type: Observational

Although obstructive sleep apnea (OSA) is a common disorder, there are no blood biomarkers for identification and management of these patients. This project will study microRNAs in order to develop and validate blood biomarkers that are specific to OSA, useful for identification of cases with OSA, reflective of efficacy of therapy, and able to predict blood pressure response to treatment of OSA.

NCT ID: NCT06188247 Recruiting - Atrial Fibrillation Clinical Trials

Pilot-trial Testing Remote Sleep Apnea Evaluation in Patients With Atrial Fibrillation

Mini VIR-SAAF
Start date: December 1, 2023
Phase: N/A
Study type: Interventional

This is an investigator-initiated virtual (or decentralized) trial that includes a postal parcel (mail-in) containing sensors for SA diagnosis (NightOwl™) and physical activity (SENS Motion), in addition to smart-phone based heart rhythm (FibriCheck) monitoring in participants with paroxysmal or persistent AF. A case-coordinator (the investigators) will manage all participant contacts virtually during the study from inclusion to follow-up.

NCT ID: NCT06167369 Recruiting - Clinical trials for Sleep Apnea, Obstructive

Biological and Cognitive Marker of Neurodegeneration in Obstructive Sleep Apnea Patients

Start date: January 1, 2024
Phase:
Study type: Observational

The goal of this observational study is to investigate biomarkers and neurocognitive markers of neurodegenerative processes in obstructive sleep apnea patients. The main questions the study aims to answer are: - Does neurodegeneration assessed by neurobiological markers and neurocognitive test performance exists in obstructive sleep apnea? - Are these neurodegenerative markers are associated with the adherence to clinical prescribed positive airway pressure therapy? Newly diagnosed patients with obstructive sleep apnea will be observed during the use of clinical prescribed positive pressure therapy. Different study related investigations take place before and six months after treatment start. Researchers will compare after six months the group of adherent treatment participants with the non-adherent treatment participants group to investigate if differences in the observed neurobiological or neurocognitive parameters exist.

NCT ID: NCT06158295 Recruiting - Pain Clinical Trials

Effects of Walking Apnea at Low Lung Volume on Hypoalgesia, Cardiovascular Function and Respiratory Function

Start date: December 1, 2023
Phase: Phase 3
Study type: Interventional

The aim of this randomized controlled study is to explore the hypoalgesic response of a 6 minutes of intermittent walking apneas training session at low lung volume in healthy subjects; also, as secondary objectives, to analyze the cardiovascular and respiratory response produced during the intervention.

NCT ID: NCT06158282 Recruiting - Pain Clinical Trials

Effects of Walking Apnea at High Lung Volume on Hypoalgesia, Cardiovascular Function and Respiratory Function

Start date: December 1, 2023
Phase: Phase 3
Study type: Interventional

The aim of this randomized controlled study is to explore the hypoalgesic response of a 6 minutes of intermittent walking apneas training session at high lung volume in healthy subjects; also, as secondary objectives, to analyze the cardiovascular and respiratory response produced during the intervention.