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Analgesia clinical trials

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NCT ID: NCT05764616 Completed - Surgery Clinical Trials

Parasternal Block Combined With Rectus Sheath Block for Cardiac Surgery Under Sternotomy

PARARECTUS
Start date: March 21, 2023
Phase: N/A
Study type: Interventional

The aim of this randomized controlled trial is to examine the effect of ultrasound guided bilateral Parasternal Nerve Block combined with rectus sheath block on preoperative analgesia, opioid consumption and respiratory function in patients undergoing cardiac surgery via sternotomy. Half of participants will receive General Anesthesia combined with bilateral parasternal block and rectus sheath block while the other half receive General Anesthesia combined with bilateral parasternal block and infiltration of drainage exits sites with local anesthetic (without performing rectus sheath block)

NCT ID: NCT05763810 Active, not recruiting - Analgesia Clinical Trials

Comparing Different Regional Blocks for Analgesia After Off-pump Cardiac Surgery

Start date: March 15, 2023
Phase: N/A
Study type: Interventional

This study aims to compare the analgesic effects of erector spinae plane block versus Superficial Parasternal Intercostal Plane Block block along with rectus sheath block after off-pump cardiac surgery

NCT ID: NCT05758233 Completed - Analgesia Clinical Trials

The Effect of Peripheral Nerve Blocks on Postoperative Analgesia in Elective Cesarean Section

Start date: January 4, 2022
Phase: N/A
Study type: Interventional

The goal of this prospective randomized study was to compare the efficacy of transversus abdominis plane block and transversalis fascia plane block for postoperative analgesia in patients undergoing elective cesarean section under spinal anesthesia. The main question[s] it aims to answer are: [Is transversalis fascia plane block more effective in postoperative analgesia? ] [Is there a difference between the duration of postoperative first analgesia requirement? ] Since the pain scores after the block at the end of the operation will be evaluated during the postoperative 24 hours, the participants will be asked to give a value between 0 and 10 in certain time periods.

NCT ID: NCT05758090 Completed - Analgesia Clinical Trials

Newborn Infant Parasympathetic Evaluation (NIPE) for Guiding Intraoperative Fentanyl in Children Under 2 Years

Start date: March 10, 2023
Phase: N/A
Study type: Interventional

During general anesthesia, objective monitoring for analgesia is still lacking. The administration of opioids relies on the experience of the anesthesiologist. There are some monitors, e.g., Analgesia Nociception Index (ANI), showing that they can evaluate analgesia in adults. Recently, a Newborn Infant Parasympathetic Evaluation (NIPE) monitor was released for assessing analgesia in children with age less than 2 years. The investigators aim to assess the efficacy of NIPE as a guide for intraoperative fentanyl administration in children under 2 years.

NCT ID: NCT05752734 Completed - Anesthesia Clinical Trials

Preoperative Dexamethasone to Improve Quality of Recovery After Laparoscopic Bariatric Surgery

Start date: February 2, 2023
Phase:
Study type: Observational [Patient Registry]

In the obese patient, adequate pain relief in the postoperative period is an important parameter that affects patient comfort and hospital stay. Increasing patient comfort and recovery quality can be achieved by avoiding undesirable effects such as nausea and vomiting, as well as analgesia. In our study, our aim is to evaluate the effect of dexamethasone added to multimodal analgesia on postoperative patient comfort in the obese patient group with a 40-item scale.

NCT ID: NCT05723341 Completed - Anesthesia Clinical Trials

Comparison of Paravertebral Block and Subcostal Transversus Abdominis Plane Block in Laparoscopic Nephrectomy

Start date: February 15, 2023
Phase: N/A
Study type: Interventional

Most of the patients undergoing laparoscopic partial/radical nephrectomy can experience moderate or severe postoperative pain, and inadequate control of this pain can cause negative consequences such as development of chronic pain, pulmonary and cardiac events, and side effects of long term opioid usage. Due to these adverse outcomes, ultrasonography-guided plane blocks can be beneficial for these patients to decrease opioid consumption. In this study, the investigators aim to compare ultrasonography-guided plane blocks: Paravertebral block and subcostal transversus abdominis plane block and traditional method: patient controlled analgesia with opioids. The investigators hypothesized that analgesic efficacy in both paravertebral and subcostal TAP blocks will have similar outcomes but better than traditional method.

NCT ID: NCT05717361 Recruiting - Pain, Postoperative Clinical Trials

Opioid Sparing Anesthesia in Cervical Spine Surgery

Start date: November 1, 2022
Phase: N/A
Study type: Interventional

The aim of this double blind randomized study will be to investigate the effect of an opioid-free anesthesia regimen with a mixture of lidocaine and ketamine in the same syringe versus remifentanyl analgesia in cervical spine surgery.

NCT ID: NCT05715437 Not yet recruiting - Analgesia Clinical Trials

Adductor Canal Block in Total Knee Arthroplasty

Start date: March 2023
Phase: Phase 4
Study type: Interventional

The purpose of this study is to evaluate whether adding ketamine to bupivacaine is superior to bupivacaine alone in terms of providing better pain control for 48 hours postoperatively after TKA.

NCT ID: NCT05713643 Completed - Analgesia Clinical Trials

ESPB vs PVB vs QLB After Pelvi-ureteric Surgeries

Start date: January 30, 2023
Phase: N/A
Study type: Interventional

The aim of this study is to compare the analgesic efficacy of erector spinae plane block versus thoracic paravertebral block versus quadratus lumborum block on postoperative analgesia after pelvi-ureteric surgeries.

NCT ID: NCT05705739 Completed - Analgesia Clinical Trials

Ultrasound Guided Erector Spinae Plane Block Versus Retrolaminar Plane Block

Start date: February 10, 2023
Phase: N/A
Study type: Interventional

Retrolaminar block (RLB) and erector spinae plane block (ESPB) are alternative approaches to paravertebral block (PVB) and are advantageous in that they are easier and safer techniques compared with the traditional PVB. These blocks are considered to be compartment blocks or interfascial plane blocks. In these approaches, local anesthetics are assumed to penetrate the superior costotransverse ligament and reach the paravertebral space, although the needle tip is not advanced into the paravertebral space. the study aim to evaluate and compare the analgesic efficacy of retrolaminar plane block and erector spinae plane block.