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Analgesia clinical trials

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NCT ID: NCT05514431 Enrolling by invitation - Anesthesia Clinical Trials

Conversion of Labor Analgesia for Intrapartum Cesarean Delivery: DPE v CSE v Epidural

Start date: February 1, 2017
Phase:
Study type: Observational

As the dural puncture epidural (DPE) is increasing in popularity for labor analgesia, it is important to understand how it impacts outcomes in parturients. Prior studies have found epidural catheters placed via the combined-spinal epidural technique have greater success at surgical conversion for cesarean delivery than catheters placed via traditional techniques. The investigators aim to determine if epidural catheters placed by a DPE technique will also have an increased successful conversion for surgical anesthesia by conducting a retrospective review of all CD during the study period. If an association is found, this could be another benefit of DPE for labor analgesia.

NCT ID: NCT05315596 Enrolling by invitation - Pain, Postoperative Clinical Trials

Longitudinal Assessment of Pain-Related Patient-Reported Outcomes After Surgery

Start date: February 1, 2022
Phase:
Study type: Observational [Patient Registry]

Little is known about pain-related outcomes experienced by patients in the first few weeks after surgery, once they are discharged from hospital. This study aims to characterize pain, pain-related interference, and early neuropathic pain in the sub-acute phase after surgery.

NCT ID: NCT04834427 Enrolling by invitation - Postoperative Pain Clinical Trials

Safety and Efficacy Evaluation of S (+) - Ketamine in Children

Start date: April 20, 2022
Phase: Phase 4
Study type: Interventional

A multicenter, randomized, open-label, active controlled pragmatic clinical trial that evaluates the safety and efficacy of S (+) -ketamine for postoperative acute pain in children in perioperative settings.

NCT ID: NCT04217434 Enrolling by invitation - Pain, Postoperative Clinical Trials

Comparative Evaluation of Various Patient Centered Outcomes Following Gingival Depigmentation Using Diode LASER in Different Modes: A Randomized Clinical Trial

LASER
Start date: November 20, 2018
Phase: N/A
Study type: Interventional

Purpose of this study is to clinically evaluate and compare various patient centered outcomes using diode LASER in Continuous mode (CW) and Pulsed Mode (PM) using 300µm and 400µm fiber for depigmentation procedure.

NCT ID: NCT03572686 Enrolling by invitation - Analgesia Clinical Trials

Dexamethasone at Lower Concentration Ropivacaine in the Supraclavicular Nerve Block

Start date: April 13, 2018
Phase: N/A
Study type: Interventional

The supraclavicular brachial plexus block is widely used in upper limb surgery below the shoulder. However, this can easily lead to long-term motor nerve blockage, Horner's syndrome, phrenic nerve paralysis or systemic poisoning, and even serious side effects such as cardiac arrest. Dexamethasone is a synthetic corticosteroid and becoming more common to use steroids as an adjunct to local anesthetics in brachial plexus block. In order to reduce the incidence of long-acting topical anesthetics from the nerve block in the supraclavicular arm, reducing the local anesthetic concentration is a feasible method, but this will also result in a shorter time to neurological block. The investigators hypothesized that the addition of Dexamethasone 5 mg to low concentrations (0.25%) of Ropivacaine would prolong postoperative analgesia.Therefore, the purpose of this study was to compare the postoperative analgesia and the side effects of postoperative supraclavicular brachial plexus blockade with the addition of Dexamethasone 5mg to Ropivacaine (0.5%) alone and Ropivacaine (0.25%) in low concentrations.