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Adolescent clinical trials

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NCT ID: NCT06358898 Not yet recruiting - Depression Clinical Trials

Digital Mood-enhanced CBT-I to Improve Depressive Symptoms in Adolescents

Start date: April 18, 2024
Phase: N/A
Study type: Interventional

Emerging encouraging evidence showed that sleep focused treatment can simultaneously improve sleep and depression in adult with comorbid conditions. Although these favorable changes in depressed adults is encouraging, little is known in the potential efficacy of CBT-I in altering depression trajectory in adolescent population. This current study aims to compare the effect of digitally delivered, mood enhanced cognitive behavioral therapy for insomnia (M-dCBT-I) and standard digital cognitive behavioral therapy for insomnia (dCBT-I) in improving depressive symptoms in adolescents, and to examine the potential sustained treatment effect in mood outcomes following M-dCBT-I or dCBT-I treatment.

NCT ID: NCT06324864 Recruiting - Depression Clinical Trials

START NOW Adapted: Culturally Adapted Version of START NOW

Start date: March 13, 2024
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to test the effectiveness of the culturally adapted skills-training START NOW in youth migrant populations. The main question it aims to answer is: Is the culturally adapted skills training START NOW more effective than treatment as usual (TAU) in reducing mental health problems in migrants? Participants will be randomly assigned to the intervention group receiving the skills training START NOW Adapted or the control group receiving TAU. Researchers will compare both groups to see if START NOW Adapted is more effective than TAU in reducing mental health problems in migrants.

NCT ID: NCT06320626 Recruiting - Child Clinical Trials

Pharmacokinetic-guided Dosing of Emicizumab

DosEmi
Start date: September 8, 2022
Phase: Phase 4
Study type: Interventional

The goal of this multicentre, prospective, open-label, cross-over clinical study is to determine whether individualized PK-guided dosing of emicizumab is non-inferior to conventional dosing of emicizumab in the prevention of bleeding in congenital haemophilia A patients.

NCT ID: NCT06275191 Not yet recruiting - Acute Pain Clinical Trials

Alternatives to Dental Opioid Prescribing After Tooth Extraction

ADOPT
Start date: April 2024
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to test a three-item intervention in oral surgeons who remove teeth. The main questions it aims to answer are: - Can the intervention reduce opioid prescriptions to adolescents and young adults after tooth removal? - Do oral surgeons' beliefs about the intervention and opioid prescribing change? - Do patients that report using opioids after tooth removal have different experiences than patients that do not? Oral surgeon participants will: - Attend a 1-hour education session with a trained pharmacist - Receive patient instructions and blister packs of pain medicine to give to patients - Complete 2 surveys about feasibility and appropriateness Patient participants will complete a survey about pain and medication use after having a tooth removed. Researchers will compare the intervention to usual care to see if it reduces opioid prescribing.

NCT ID: NCT06249880 Recruiting - Pediatric ALL Clinical Trials

Pediatric Normative Markerless Movement Analysis

Start date: February 14, 2024
Phase:
Study type: Observational

The objective of this project is to collect baseline data from a normative population of children that gender and age matches the population of patients expected to be treated by Mary Bridge Children's Research & Movement Lab. This project seeks to recruit 20 male and 20 female typically developing individuals, between the ages of 3 and 25 years of age. Non-invasive measurements of movement patterns (motion analysis and force plate data) will be collected during bipedal gait.

NCT ID: NCT06214637 Recruiting - Children Clinical Trials

Effectiveness of Melissa Officinalis for the Treatment of Probable Sleep Bruxism in Children and Adolescents

Start date: August 1, 2023
Phase: Phase 1
Study type: Interventional

Objective: To investigate, through a controlled and randomized clinical trial, the effectiveness of using Melissa officinalis in different concentrations in the treatment of children and adolescents with probable sleep bruxism. Methodology: This is a randomized, triple-blind, crossover, and placebo-controlled clinical trial. The research participants will be children aged 5 to 10 years old and adolescents aged 11 to 16 years old who attend dental treatment at the FO/UFRJ Pediatric Dentistry Clinics. After approval by the Human Research Ethics Committee, children and adolescents will undergo homeopathic treatment with Melissa officinalis in different concentrations for possible sleep bruxism. In addition, research participants will undergo an assessment of TMJ, sleep, circadian cycle, quality of life, and quality of life related to oral health. The data will be tabulated and analyzed according to sex, age group, presence of possible sleep bruxism, presence or absence of TMD, circadian characteristics, presence or absence of sleep disorders, daytime and nighttime behavioral characteristics. The data will be tabulated and evaluated using SPSS 21.0. Absolute and relative frequency, odds ratio, correlation analysis and other relevant analyzes and statistical tests (p<0.05) will be carried out in accordance with the objectives proposed by the study

NCT ID: NCT06211517 Not yet recruiting - Anorexia Nervosa Clinical Trials

Drugs Experience for Adolescents With Anorexia

E3P
Start date: January 2024
Phase:
Study type: Observational

The purpose of this study is to access to the experiences of adolescents, their parents and healthcare professionals regarding psychotropic drugs in anorexia nervosa. No preconceived ideas (according to qualitative methods) but a question: what are the participants' perceptions and experiences of psychotropic drugs in anorexia nervosa? In an adolescent medicine department.

NCT ID: NCT05999994 Recruiting - Neoplasms Clinical Trials

A Master Protocol (LY900023) That Includes Several Clinical Trials of Drugs for Children and Young Adults With Cancer

CAMPFIRE
Start date: January 22, 2020
Phase: Phase 2
Study type: Interventional

The main purpose of the master is to help the research sites and sponsor carry out several clinical trials more efficiently by providing a common research protocol. Individual clinical trials under this master protocol define drug/disease-specific research goals and activities to test them. New studies will be added as new drugs emerge against different cancers. Participation in the trial will depend on how long the benefit lasts.

NCT ID: NCT05986175 Recruiting - Adolescent Clinical Trials

The Effect of Motor Imagery Training in Addition to Core Stabilization Exercises on Core Performance, Balance, Functional Capacity, and Quality of Life in Healthy Adolescents Girls

Start date: June 1, 2023
Phase: N/A
Study type: Interventional

Adolescence is the period in which a person grows and develops the fastest, covering the transition from childhood to maturity. Compared to sedentary adolescents who regularly exercise, there were significant differences in levels of functional capacity, cognitive function, and quality of life. The balance that shows significant development in the adult period, if not sufficiently developed, results in a lack of proper balance during movements, making individuals exposed to injuries. A strong "core" area is needed to ensure the stabilization of the whole body and increase functional capacity. In the studies carried out, the "core" exercise programs resulted in increased lumbopelvic stability, improved small and large muscle strength, and increased body control and balance. Motor imagery is defined as the resurrection of movement in the mind before movement occurs. For individuals with health or health-related problems, it has been found that the implementation of imaging tasks is beneficial, either alone or in addition to physical practice and that similar brain regions are activated during the performance of the movement and imaging the movement. 56 healthy girls will be included in our study. The participants will be randomly divided into 2 groups, including 28 control groups and 28 training groups. The core performance will be assessed with the Modified Push-Up Test and Sit-Up Test. The Flamingo test will be used to assess static balance and the Y test will be used to assess dynamic balance. Quality of life will be assessed with the Pediatric Quality of Life Questionnaire (PedsQL) for adolescents aged 13-18 years. Functional capacity will be assessed with the 6-Minute Walk Test. Exercise Readiness Questionnaire will be used to measure exercise readiness. The Movement Imagery Questionnaire-Revised (MIQ-R) form will be used for motor imagery; the Vividness of Motor Imagery Questionnaire (VMIQ) will be used for clarity and vividness of motor imagery. During the motor imagery training, heart rate will be measured to determine whether the participant performs the imagery correctly. In addition to all of these assessments, the values of Heart Rate, Blood Pressure, Saturation, Dyspnea, and Fatigue Levels (Modified Borg Dyspnea and fatigue scales) will be recorded. The control group will be subject to Jeffreys' core (body) stabilization training protocol. The training group will receive engine simulation training in addition to Jeffreys' core (body) stabilization training protocol. The control group and the training group will implement training programs with a physiotherapist 3 times a week for 8 weeks. All assessments will be repeated before and after the 8-week training program. The aim of the present study is to investigate the effect of motor imagery training given in addition to core stabilization training on core performance, balance, functional capacity, and quality of life in healthy adolescent girls.

NCT ID: NCT05979272 Recruiting - Cannabis Use Clinical Trials

TECH App Marijuana Use Intervention for Court-Involved Adolescents

TECH
Start date: June 21, 2023
Phase: N/A
Study type: Interventional

The study is about helping teens who are involved in the court system to cut down or quit using marijuana. Teens may be asked to test out an experimental smartphone app, called TECH, that will be used only by teens in this study. This app is a private online community where teens can work towards changing their substance use and other behavior with the help of other anonymous teens. We will use this information to learn how the app may help teens make a change and to improve the TECH app.