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Abdomen, Acute clinical trials

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NCT ID: NCT04681508 Recruiting - Acute Kidney Injury Clinical Trials

MINS, AKI and Pulmonary Pathology in Patients Undergoing Acute Abdominal Surgery

Start date: March 1, 2021
Phase: N/A
Study type: Interventional

Explorative study to investigate potential predictors of myocardial injury, acute kidney injury and pulmonary disorder after acute high-risk abdominal surgery.

NCT ID: NCT04662242 Not yet recruiting - Sepsis Clinical Trials

The Prognostic Impact of Selenium On Critical Surgical Patients

Start date: December 2020
Phase: Phase 4
Study type: Interventional

Selenium is an important trace element for human for its multiple roles such as the antioxidant activity. Previous evidences showed that critically ill patients may benefit from selenium supplement but the dose and results are controversial. Patients after operations for acute abdomen usually suffer from sepsis and stress. The aim of this study is to investigate the efficacy of selenium replacement in critical patients of acute abdomen, to see the impact on prognosis.

NCT ID: NCT04602429 Recruiting - Surgery Clinical Trials

Children's Acute Surgical Abdomen Programme

Start date: September 30, 2019
Study type: Observational

To describe the type and quality of care being delivered to children (aged 1 - 16 years old) undergoing emergency abdominal surgery in the United Kingdom by measuring baseline compliance against evidence-based recommendations and identifying variations in care between individual hospitals.

NCT ID: NCT04584060 Not yet recruiting - Clinical trials for Patient Undergoing Urgent GIT Surgery

Conventional VS Enhanced Recovery After Surgery Protocols in Emergency GIT Surgery

Start date: December 1, 2020
Study type: Observational [Patient Registry]

Although the ERAS program is widely used in elective procedures in many surgical subspecialties, the place of this program in emergency surgery remains uncertain probably because of the significant challenges in applying all ERAS pathways in the emergency setting. Nevertheless, the ERAS program is often modified in elective procedures on an individual and/ or institutional basis and thus may also have a role in the emergency setting albeit in a modified form.

NCT ID: NCT04577339 Not yet recruiting - Peritonitis Clinical Trials

The Best Care for Abdominal Emergencies Study

Start date: December 1, 2020
Study type: Observational

This is a single-centre retrospective cohort study utilising electronic hospital records. The aim of this study is to improve care for all patients with an intestinal emergency, irrespective of whether they have surgery or not. Data will be derived from electronic patient records collected as part of routine clinical patient care on all general adult wards (excluding maternity) between 2013 and 2020. We will then identify patients who had an emergency laparotomy, and those who had a laparoscopic procedure. We aim to identify 2 further groups where treatment is non-surgical (but could be medical or interventional radiology) or where treatment is considered futile, suggesting that an early focus on end of life care might be appropriate. The primary objective is to provide mortality rates for different treatment options, and analysis of short- and long-term outcomes. The secondary endpoints are to define patient sub-groups with similar health characteristics based on clinical data and an established risk index and to use statistical analysis to predict the risk of death for each patient group and treatment option, which will allow us to identify the best care pathways for each cluster.

NCT ID: NCT04480983 Not yet recruiting - Clinical trials for Acute Abdomen in Children

Role of Multidetector Computerized Tomography (MDCT) in Diagnosis of Non Traumatic Acute Abdomen in Pediatric Age Group.

Start date: December 1, 2021
Study type: Observational

To evaluate the role of MDCT in diagnosis of non traumatic causes of acute abdomen in pediatric patients with clinical and surgical correlation.

NCT ID: NCT04196244 Recruiting - Acute Abdomen Clinical Trials

Intravenous Contrast Computed Tomography Versus Native Computed Tomography in Patients With Acute Abdomen and Impaired Renal Function

Start date: September 18, 2020
Phase: Phase 4
Study type: Interventional

Computer tomography (CT) is the primary imaging option for acute abdominal pain in adults. Intravenous (IV) contrast media is used to improve the CT quality. In patients with impaired renal function, post-contrast acute kidney injury (PC-AKI) has remained a significant concern. Modern retrospective studies have shown no association between worsened baseline renal function and IV-contrast CT. However, no randomised controlled trial has been done to conclude this. The INCARO (INtravenous Contrast computed tomography versus native computed tomography in patients with acute Abdomen and impaired Renal functiOn) trial is a multicentre, open-label, parallel group, superiority, individually randomised controlled trial comparing IV-contrast enhanced CT to native CT in patients with impaired renal function. Patients requiring emergency abdominal or body CT with eGFR 15-45 ml/min/1.73 m2 are included in the study. The primary outcome is a composite outcome of all-cause mortality or renal replacement therapy within 90 days from CT.

NCT ID: NCT04176432 Completed - Clinical trials for Postoperative Complications

Survival After Emergency Laparotomy in Octogenarians

Start date: January 1, 2015
Study type: Observational

In this single-center retrospective study we wanted to investigate mortality and postoperative complications after emergency laparotomy performed in patients aged 80 years or above.

NCT ID: NCT03902262 Completed - Appendicitis Clinical Trials

Acute Abdomen in Kawasaki Disease

Start date: April 14, 2016
Study type: Observational

Clinical and histopathological description of three cases of Kawasaki disease with acute abdomen.

NCT ID: NCT03549624 Recruiting - Peritonitis Clinical Trials

Standardized Perioperative Management of Patients Operated With Acute Abdominal Surgery in a High-risk Emergency Setting

Start date: February 26, 2018
Study type: Observational

The objective of the study is to handle patients with the need for an acute laparotomy according to a standardised perioperative protocol and to document the measurement as they are performed (i.e. adherence to the protocol) and to measure the outcome with regard to both short- (30 days) and long-term (3 and 12 months) mortality. Several secondary endpoints will be measured, such as: hospital stay, length of stay at an Intensive Care Unit (ICU), readmission to ICU and surgical complications according to the Clavien-Dindo score. These results will then be compared to published rates of mortality from the literature and to similar outcomes for a cohort of all patients operated at NÄL on the same indication the years prior to the project/study.