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Syndrome clinical trials

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NCT ID: NCT01325740 Suspended - Fragile X Syndrome Clinical Trials

A Study to Assess the Tolerability of a Single Dose of STX107 in Adults With Fragile X Syndrome

Start date: May 2011
Phase: Phase 2
Study type: Interventional

The study will consist of a Screening period (up to 14 days), a Treatment period, and a Follow-Up period. Sixteen subjects will be enrolled into two sequential dose cohorts - 10 or 30 mg (or matching placebo) across four study centers.

NCT ID: NCT01151176 Suspended - Clinical trials for Acute Coronary Syndrome

Feasible Insulin Algorithm for Glycemic Control in Patients With Acute Coronary Syndrome

Start date: August 2012
Phase: Phase 4
Study type: Interventional

The study aims to demonstrate that a simple intravenous insulin algorithm can be implemented in Latin America and will result in safe and better glucose control in patients with Acute Coronary Syndrome (ACS) compared with SC insulin.

NCT ID: NCT01076699 Suspended - Clinical trials for Irritable Bowel Syndrome

A Four Arm Study to Evaluate the Safety and Efficacy of 3 Different Doses of RVX-100 Versus Placebo in Subjects With Irritable Bowel Syndrome Accompanied by Diarrhea (IBS-D)

Start date: March 2010
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine if RVX-100 is safe and effective in treating acute abdominal pain in patients with irritable bowel syndrome accompanied by diarrhea.

NCT ID: NCT01010373 Suspended - Clinical trials for Acute Myeloid Leukemia

Safety and Efficacy Study of AS101 to Treat Elderly Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS) Patients

Start date: January 2015
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine whether addition of AS101 to the standard chemotherapy regimen is effective in the treatment of newly diagnosed elderly (≥60) AML patients and AML transformed myelodysplastic syndrome (MDS) patients.

NCT ID: NCT00978224 Suspended - Clinical trials for Chronic Inflammatory Syndrome

Viusid Administration in Subjects With Chronic Inflammatory Syndrome Under Hemodialysis Treatment

Start date: October 2009
Phase: Phase 3
Study type: Interventional

The purpose of the study is to determine whether Viusid administration improves malnutrition, atherosclerosis, erythropoietin response and the frequency of infection episodes in subjects with Chronic Inflammatory Syndrome under hemodialysis treatment. The duration of this double-blind placebo controlled phase 3 clinical trial will be 60 weeks. All patients enrolled in the study will be receiving the standard treatment for Chronic Inflammatory Syndrome including hemodialysis and administration of a hypercaloric and hyperproteic diet. Efficacy assessment will be carried out 12 weeks after the end of Viusid or placebo treatment.

NCT ID: NCT00935090 Suspended - Lymphoma Clinical Trials

3'-Deoxy-3'-[18F] Fluorothymidine PET Imaging in Patients With Cancer

Start date: September 2009
Phase: N/A
Study type: Interventional

RATIONALE: Diagnostic procedures, such as 3'-deoxy-3'-[18F] fluorothymidine (FLT) PET imaging, may help find and diagnose cancer. It may also help doctors predict a patient's response to treatment and help plan the best treatment. PURPOSE: This phase I trial is studying FLT PET imaging in patients with cancer.

NCT ID: NCT00433173 Suspended - Metabolic Syndrome Clinical Trials

Insulin Sensitivity in Men With the Metabolic Syndrome

Start date: May 2006
Phase: N/A
Study type: Interventional

The metabolic syndrome is a medical condition defined by high levels of cholesterol in the blood, high blood pressure, central obesity (gain in fat around the region of the stomach), and insulin resistance (body responds less well to insulin). This state of impaired insulin resistance can lead to type 2 diabetes mellitus, which is one of the most common metabolic disorders in the U.S. Numerous studies have shown an inverse relationship between insulin resistance and testosterone levels in men, however, causality has not been established. This protocol investigates the role of testosterone in modulating insulin sensitivity in insulin resistant states such as the metabolic syndrome. The hypothesis is that testosterone administration will improve insulin sensitivity.

NCT ID: NCT00329498 Suspended - Clinical trials for Acute Myeloid Leukemia

L-Ascorbic Acid Depletion to Treat Acute Myeloid Leukemia and Myelodysplastic Syndromes

Start date: May 1998
Phase: Phase 2
Study type: Interventional

To document therapeutic gain achieved by cyclic application of L-ascorbic acid (LAA) supplementation and depletion, while confirming safety and avoidance of clinically significant scurvy, in chemorefractory patients with acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS).

NCT ID: NCT00287664 Suspended - Cirrhosis Clinical Trials

Treatment of Hepatorenal Syndrome With Terlipressin Plus Albumin vs Albumin

Start date: February 2002
Phase: Phase 4
Study type: Interventional

Hepatorenal syndrome is a common complication of cirrhotic patients. The prognosis of patients with HRS is very poor. It have been demonstrated that vasoconstrictors agents (Terlipressin) plus albumin are effective in the reversal of the treatment. However, previous studies are pilot studies and they are not able to give information about an improvement in survival. This comparative randomized study was delineated to test the efficacy of terlipressin on survival.

NCT ID: NCT00243984 Suspended - Clinical trials for Diabetes Mellitus, Type 2

Efficacy of Topiramate for Weight Loss in Subjects With Metabolic Syndrome

Start date: March 2005
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the efficacy of topiramate compared to placebo in the treatment of obesity in metabolic syndrome. Secondary objectives include topiramate and weight loss effects on lipid levels, HbA1C, insulin resistance, and blood pressure.