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Syndrome clinical trials

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NCT ID: NCT03434704 Not yet recruiting - Clinical trials for Myelodysplastic Syndromes

Phase II Trial of Peripheral Blood Stem Cell Transplantation From Family Haploidentical Donors in Patients With Myelodysplastic Syndrome and Acute Leukemia Under Primary Prophylaxis With Posaconazole

SIR-POSA
Start date: March 15, 2018
Phase: Phase 2
Study type: Interventional

SIR-POSA is a phase II trial of peripheral blood stem cell (PBSC) transplantation from a partially compatible family (Haplo) donor in patients with a blood tumor (myelodysplastic syndrome (MDS) and acute leukemia) treated for the prevention of primary fungal infections with posaconazole. The aim is evaluate the composite end-point graft-versus-host disease-free, relapse-free survival (GRFS) in these patients and evaluate the feasibility and efficacy of posaconazole oral tablets as primary antifungal prophylaxis.

NCT ID: NCT03434652 Recruiting - Clinical trials for Cyclic Vomiting Syndrome

Auricular Neurostimulation for Cyclic Vomiting Syndrome

Start date: January 31, 2018
Phase: N/A
Study type: Interventional

This study evaluates the efficacy of auricular neurostimulation via an non-invasive percutaneous electrical nerve field stimulator in children and adults with cyclic vomiting syndrome.

NCT ID: NCT03434106 Recruiting - Clinical trials for Meibomian Gland Dysfunction

Sjögren's Syndrome Is Associated With Meibomian Gland Dysfunction

Start date: February 10, 2018
Phase: N/A
Study type: Interventional

The investigators hypothesize that the dry eye caused by SS may include the evaporative type, resulting from the MGD. Furthermore, the investigators hypothesize that both pSS and sSS are associated with MGD.To test our hypothesis, we conducted a prospective clinical study in patients with SS (both pSS and sSS) and MGD, and the normal population All subjects were matched for both age and gender and assessed for tear function and ocular surface signs and symptoms.

NCT ID: NCT03433781 Not yet recruiting - Clinical trials for Myelodysplastic Syndromes

Tolerability of Vitamin C in Patients With Intermediate or High Risk Myelodysplastic Syndrome With TET2 Mutations

Start date: February 26, 2018
Phase: Phase 1/Phase 2
Study type: Interventional

This is an open label, Phase Ib/IIa study designed to evaluate the safety, toxicity and biological activity of high dose Vitamin C in bone marrow and peripheral blood when administered as therapy to patients with intermediate or high risk myelodysplastic syndrome according to the revised IPSS (international prognostic scoring system) criteria whose disease has a Ten-eleven translocation-2, (TET2) mutation.

NCT ID: NCT03432078 Active, not recruiting - Clinical trials for IBS - Irritable Bowel Syndrome

Individual vs. Group Hypnotherapy in Patients With Irritable Bowel Syndrome

Start date: August 15, 2011
Phase: N/A
Study type: Interventional

Patients' fulfilling Rome III criteria for IBS with symptoms refractory to standard treatment who are referred to a specialist unit for hypnotherapy are consecutively included in the study. The patients are randomized to either individual or group treatment given by a nurse trained in hypnotherapy. The treatment consists of eight sessions of gut directed hypno therapy during twelve weeks. Effects are measured by validated questionnaires at baseline and at various time points during the treatment period as well as after the completion of the treatment.

NCT ID: NCT03431480 Not yet recruiting - Clinical trials for Heart Defects, Congenital

Safety of Autologous Cord Blood Cells in HLHS Patients During Norwood Heart Surgery

Start date: February 26, 2018
Phase: Phase 1
Study type: Interventional

This study aims to evaluate the safety and feasibility of coronary infusion of autologous placental cord blood mononuclear cells during the Norwood heart operation in newborn hypoplastic left heart syndrome (HLHS) patients.

NCT ID: NCT03429517 Not yet recruiting - Clinical trials for Dyslipidemia Associated With Acute Coronary Syndrome

Changes in Triglycerides, HDL-C and Cholesterol in ACS Patients

Start date: May 1, 2018
Phase: N/A
Study type: Observational

Background Changes in high-density lipoprotein cholesterol and triglyceride levels have been linked to residual cardiovascular risk, whereas non-high density lipoprotein levels have been shown to be more predictive of cardiovascular risk than are low-density lipoprotein cholesterol levels. We aimed to investigate the impact of high density lipoproteins, triglyceride, and non-high density lipoproteins levels on acute coronary syndrome risk with on-target low density lipoproteins levels.

NCT ID: NCT03428451 Not yet recruiting - Clinical trials for Transurethral Resection of Prostate Syndrome

Treatment Versus Prophylaxis Against TURP Syndrome: Role Of Hypertonic Saline

Start date: February 2018
Phase: N/A
Study type: Interventional

The study is designed to evaluate the efficacy and safety of intravenous infusion of hypertonic saline in BPH patients, candidates for TURP surgery using the monopolar electric resectoscope in prevention of hyponatraemia and TUR syndrome.

NCT ID: NCT03427983 Not yet recruiting - Clinical trials for Carpal Tunnel Syndrome

Hydrodissection as a Treatment for Carpal Tunnel Syndrome

Start date: February 27, 2018
Phase: Early Phase 1
Study type: Interventional

This is a pilot study designed to acquire data on the added value of hydrodissection when using a corticosteroid injection as a treatment for patients with carpal tunnel syndrome. Hydrodissection is part of a standard clinical care injection under ultrasound guidance in which the fluid is used to separate the nerve from surrounding structures.

NCT ID: NCT03426358 Recruiting - Clinical trials for Stem Cell Transplant Complications

Liver Stiffness Measurement Predicts VOD/SOS Development (ELASTOVOD ITALIAN MULTICENTRIC STUDY)

ELASTOVOD
Start date: April 28, 2015
Phase: N/A
Study type: Interventional

ELASTOVOD is a prospective multicenter study, involving several centers of Onco-haematology in Italy. Investigators perform hepatic elastographic measurements (with Transient Elastography, ARFI or 2D-SWE) on patients undergoing HSCT, at baseline before transplantation (T0) and at T1/T2/T3 after HSCT (+9/10, +15/17, +22/24). SOS/VOD diagnosis was performed according to clinical criteria.