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Neuroplasticity After Proprioceptive Rehabiliation — VibraLCA  

Stroke Clinical Trial

Official title:
Neuroplasticity Induced by Functional Muscle Tendon Vibrations in Patients With Acquired Brain Injury

Clinical Trial Summary

Sequences of muscle tendon vibrations allow to reproduce the sensory feedback during movement like locomotion and kinaesthesia. It is known that such a treatment promotes motor recovery after stroke assuming that it enhances neuroplasticity. The aim of the research is to study the activity in cerebrospinal circuitry to evaluate the neuroplastic changes during and after instrumented proprioceptive rehabilitation relying on sequences of muscle vibration in subacute stroke stages.

Clinical Trial Description

Randomized control trial : 28 patients with active vibrations vs. 28 patients with sham stimulation Subacute phase : D15 to 6 months after stroke or patients with traumatic brain injury with similar semiology as stroke (hemiparesis) Measure at baseline : Electrophysiological investigations (EMG,EEG, MRI, clinical evaluation) Treatment of 5 weeks with 3 sessions of vibrations or sham a week Evaluation at mid time (electrophysiology and clinical examinations) Final examination (electrophysiology, MRI and clinical examination) ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05277519
Study type Observational
Source Institut National de la Santé Et de la Recherche Médicale, France
Contact Veronique Marchand-Pauvert, PhD
Phone +33142161120
Email veronique.marchand-pauvert@inserm.fr
Status Recruiting
Phase
Start date June 16, 2022
Completion date November 30, 2026
View Details
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