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Traumatic Brain Injury clinical trials

View clinical trials related to Traumatic Brain Injury.

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NCT ID: NCT03343964 Not yet recruiting - Clinical trials for Traumatic Brain Injury

Amplitude-integrated EEG in Improvement of Seizure Detection and Prognostication in Children With TBI

aEEG
Start date: January 2018
Phase: N/A
Study type: Observational

The goal of this study is to determine whether the addition of aEEG to cEEG in clinical practice does in fact help PICU physicians detect subclinical seizures in this population.

NCT ID: NCT03342495 Not yet recruiting - Diabetes Clinical Trials

Evaluating Innovations in Transition From Pediatric to Adult Care - The Transition Navigator Trial

TNT
Start date: December 1, 2017
Phase: N/A
Study type: Interventional

The Transition Navigator Trial (TNT) is a pragmatic randomized controlled trial evaluating the effectiveness of usual care plus a patient navigator service versus usual care plus newsletters and other educational materials, to improve transition outcomes among adolescents aged 16-21 who have chronic health conditions requiring transfer to adult specialty care. The study will provide urgently needed data to guide health care providers and policy makers regarding the provision of coordinated transition care. These results have the potential to: 1. Change care delivery 2. Improve health outcomes 3. Improve the experiences of young adult transition to adult care

NCT ID: NCT03341572 Recruiting - Sepsis Clinical Trials

The Effect of Positive End Expiratory Pressure on Central Venous Pressure Among Patients With Different Lung Compliance

Start date: November 13, 2017
Phase: N/A
Study type: Interventional

To observe the effect of PEEP on CVP among patients with different respiratory compliance

NCT ID: NCT03339037 Recruiting - Clinical trials for Traumatic Brain Injury

Hyperbaric Oxygen Therapy Effect on Post Concussion Syndrome in Children

TBIPED
Start date: November 1, 2017
Phase: N/A
Study type: Interventional

Due its high incidence, mTBI and its consequences of PPCS are a major public health issue. There is no consensus regarding the treatment of PPCS in pediatrics. Relying on its results in adults, HBOT offers a promising new direction of treatment, which targets the basic pathological processes responsible for post-concussion symptoms. The effect of hyperbaric oxygen therapy in pediatric TBI has never been evaluated. The aim of the current study is to evaluate in a prospective cross-over, randomized study, the effect of HBOT on children with PPCS due to mild TBI.

NCT ID: NCT03321370 Not yet recruiting - Clinical trials for Traumatic Brain Injury

Cortical Spreading Depolarization After Severe Traumatic Brain Injury

Start date: November 1, 2017
Phase: N/A
Study type: Observational

Preliminary evaluation of electrodes placed on the brain for recording brain activity and novel algorithms to determine cortical spreading depolarization foci of origination following severe traumatic brain injury requiring neurosurgical intervention.

NCT ID: NCT03315273 Not yet recruiting - Healthy Clinical Trials

Measuring Motor Imagery Ability in Patients With Traumatic Brain Injury.

Start date: October 23, 2017
Phase: N/A
Study type: Interventional

1. Validation of translated Motor Imagery ability questionnaire MIQ-RS 2. Investigating the Motor Imagery ability in patients with traumatic brain injury

NCT ID: NCT03309930 Recruiting - Clinical trials for Traumatic Brain Injury

Narrative Comprehension by People With Acquired Brain Injury

Start date: October 6, 2017
Phase: N/A
Study type: Interventional

The purpose of this two phase study is to evaluate comprehension by people with acquired brain injury. The phase 1 portion of the study will examine comprehension of narrative paragraphs under 3 conditions: (a) written text only, (b) auditory output only (i.e., synthetic speech - David voice) or combined written text and auditory output. The phase 2 portion of the study is to evaluate comprehension of sentences and paragraphs produced with computer generated (synthesized) speech and digitized natural speech after multiple exposures.

NCT ID: NCT03307070 Recruiting - Clinical trials for Major Depressive Disorder

Adapted Cognitive Behavioral Treatment for Depression in Patients With Moderate to Severe Traumatic Brain Injury

Start date: September 23, 2017
Phase: N/A
Study type: Interventional

The first aim of this study is to develop a structured, cognitive behavioral treatment manual for major depressive disorder (MDD) adapted for individuals with moderate to severe traumatic brain injury (TBI) (CBTx-TBI), as well as evaluate its acceptability and tolerability in an open 12-week pilot trial (N=10). The second aim is to evaluate the acceptability and tolerability of, and adherence to, CBTx-TBI in a randomized waitlist-controlled, 12-week pilot trial (N=40). A third, exploratory aim is to evaluate the potential efficacy of CBTx-TBI for MDD in the randomized pilot trial (N=40) and possible moderators and mediators of outcome.

NCT ID: NCT03306563 Not yet recruiting - Clinical trials for Traumatic Brain Injury

Rapid Biochemical Diagnostics of Traumatic Brain Injury

Start date: November 2017
Phase: N/A
Study type: Interventional

The objective of the study is to confirm the clinical relevance of the novel biomarker for traumatic brain injury (TBI) detection. Samples of blood, urine and saliva will be collected from a) patients with suspected TBI (isolated), b) patients with orthopedic injury, and c) healthy controls. The sponsor will do biochemical investigations for the samples to evaluate the presence, level and structure of the targeted biomarker.

NCT ID: NCT03304899 Not yet recruiting - Clinical trials for Traumatic Brain Injury

Fibrinogen Concentrate in Isolated Traumatic Brain Injury

Start date: October 23, 2017
Phase: Phase 1/Phase 2
Study type: Interventional

Fibrinogen is a unique precursor of fibrin and cannot be compensated for by other coagulation factors. If plasma fibrinogen concentrations are insufficient, hemostatic clots cannot be formed with the appropriate firmness. In severe traumatic brain injury(TBI) patients, plasma fibrinogen concentrations decrease earlier and more frequently than other coagulation factors,predicting massive bleeding and death. The purpose of this study is to try early injection of fibrinogen concentrate in severe isolated traumatic brain injury and investigation the effect of it on post bleeding and complications.