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Stress Disorders, Post-Traumatic clinical trials

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NCT ID: NCT04333667 Completed - Clinical trials for Post-traumatic Stress Disorder

Effectiveness of Mindfulness-based Internet Intervention Still Me

Still-Me
Start date: April 14, 2020
Phase: N/A
Study type: Interventional

The aim of the study is to assess the effectiveness of a mindfulness-based internet intervention for post-traumatic stress disorder symptoms.

NCT ID: NCT04328935 Active, not recruiting - Clinical trials for Post Traumatic Stress Disorder

Written Exposure Therapy for Post-traumatic Stress Syndrome

Start date: October 27, 2020
Phase: N/A
Study type: Interventional

To investigate if written exposure therapy is feasible for patients with post-traumatic stress disorder

NCT ID: NCT04327362 Withdrawn - Depression Clinical Trials

tDCS-Augmented Prolonged Exposure Therapy

Start date: October 1, 2021
Phase: N/A
Study type: Interventional

The purpose of this study is to determine the effects of a brain stimulation technique known as transcranial direct current stimulation, or tDCS, on the benefits of Prolonged Exposure therapy, or PE, which is an effective treatment for posttraumatic stress disorder, or PTSD. tDCS has been demonstrated to be safe and effective for influencing brain activity by passing a weak electrical current through the scalp. In this study, tDCS is provided in addition to PE treatment, through the National Crime Victim's Research and Treatment Center at MUSC, or the PTSD Clinical Team Clinic within the Ralph H. Johnson VA Medical Center.

NCT ID: NCT04325087 Recruiting - Clinical trials for Post Traumatic Stress Disorder

Reduction of Trauma-induced Intrusions and Amygdala Hyperreactivity Via Non-invasive Brain Stimulation

COOL
Start date: July 1, 2019
Phase: N/A
Study type: Interventional

The study will focus on the modulation of intrusive memories via functional magnetic resonance imaging (fMRI)-guided repetitive transcranial magnetic stimulation of the dorsolateral prefrontal cortex (dlPFC) directly after exposure to a traumatic video.

NCT ID: NCT04317820 Recruiting - PTSD Clinical Trials

Deep Brain Reorienting in Post-traumatic Stress Disorder

Start date: September 29, 2020
Phase: N/A
Study type: Interventional

This study will evaluate the efficacy of a therapeutic treatment, Deep Brain Reorienting (DBR), for PTSD (Post-traumatic Stress Disorder). Participants will be randomized to either the DBR treatment, or wait-list condition.

NCT ID: NCT04314115 Completed - Clinical trials for Posttraumatic Stress Disorder

Prevention of Mental Health Problems in People Exposed to a Recent Highly Stressful Event.

Start date: April 1, 2018
Phase: N/A
Study type: Interventional

This project evaluates the effectiveness of three intervention models for the prevention of mental health problems in people who have suffered a recent highly stressful event, through an experimental design, with a control group and random assignment of participants in each group . The preventive interventions that will be evaluated will be based on three different psychotherapeutic models: brief systemic therapy, cognitive behavioral therapy and mindfulness. It is expected to observe a significant reduction in post-traumatic and depressive symptoms, and an increase in subjective well-being and post-traumatic growth, compared to the control group. In addition, the moderating effect of psychological processes such as cognitive rumination, emotional self-regulation and coping strategies used in the relationship between the type of intervention and its results will be evaluated. If the hypotheses are confirmed, this study will allow the prevention of emotional distress associated with a highly stressful event, as well as the promotion of positive results, through empirically supported, low-cost strategies and with results that are capable of demonstrating their effectiveness.

NCT ID: NCT04307875 Not yet recruiting - Hypertension Clinical Trials

Hypertension and Diabetes Assessment in the Rohingya Refugee Population and in the Host Communities in Bangladesh

Start date: October 1, 2021
Phase:
Study type: Observational

Due to a massive outbreak of violence against the Rohingya minority residing in the Rakhine State of Myanmar in late 2017, several hundred thousand Rohingya fled the country and sought a shelter in Bangladesh. Currently, in the refugee settlement areas east of the city of Cox's Bazar, close to 1 million Rohingya refugees live in refugee camps close to the municipalities of Ukhia and Shamlapur. According to previous examinations, there is a serious burden of non-communicable diseases in Bangladesh. But little is known about the health status and the epidemiology of non-communicable diseases in the Rohingya refugee population in Bangladesh. Most importantly, scientific evidence on non-communicable disease in humanitarian emergencies is rather limited. The aim of this study is to close this gap and to systematically assess the burden of hypertension and diabetes within the Rohingya refugee population in refugee camps in Bangladesh and in the host community in the Chittagong province. This assessment will help to design and to introduce community-based intervention strategies aiming to improve the population health status and reduce the disease burden.

NCT ID: NCT04307498 Completed - Clinical trials for Posttraumatic Stress Disorder

Predicting Treatment Outcomes With Intensive Outpatient Treatment for PTSD

PTSD
Start date: November 26, 2019
Phase: N/A
Study type: Interventional

The open-label clinical study explores potential modifiable predictors of treatment outcomes in a sample of 55 military service members and veterans with clinically significant PTSD symptoms who receive Intensive Outpatient Prolonged Exposure (IOP-PE).

NCT ID: NCT04304378 Recruiting - Clinical trials for Post-Traumatic Stress Disorder

Trauma Informed Treatment Algorithms for Novel Outcomes

TITAN
Start date: October 5, 2020
Phase: N/A
Study type: Interventional

This randomized controlled trial (RCT) will examine the feasibility, acceptability, and preliminary efficacy of a beginning treatment for Post-Traumatic Stress Disorder (PTSD) with Behavioral Activation (BA). Cambodian men and women who screen positive for PTSD will be randomized to receive six individually delivered sessions of either: 1) Stabilization Techniques alone (ST); or 2) ST+BA. After two months, all participants who continue to report clinically meaningful elevations in PTSD will receive Eye Movement Desensitization Reprocessing (EMDR). All participants will complete a follow-up assessment at four months post-randomization.

NCT ID: NCT04302181 Completed - Clinical trials for Stress Disorders, Post-Traumatic

Augmenting Massed Prolonged Exposure With a Stellate Ganglion Block to Treat PTSD

Start date: October 5, 2020
Phase: Early Phase 1
Study type: Interventional

This is a small, open-label treatment study that tests the potential safety and treatment effectiveness of a stellate ganglion block combined with Massed Prolonged Exposure (PE). Each of the 12 participants will receive ten 90-minute sessions of Massed Prolonged Exposure and an injection of a stellate ganglion block between the first and second PE sessions.