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Stress Disorders, Post-Traumatic clinical trials

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NCT ID: NCT00262223 Completed - Clinical trials for Substance-Related Disorders

Combined Treatment for Alcohol-Dependent Individuals With PTSD

Start date: May 2006
Phase: Phase 2
Study type: Interventional

This treatment intervention trial is designed for men and women with either alcohol misuse (e.g. hazardous or binge drinking) or alcohol use disorders (alcohol abuse or dependence) and comorbid PTSD. Participants will be randomly assigned to one of two treatments (a cognitive behavioral treatment intervention called "Seeking Safety" + Medication ("Zoloft") or Seeking Safety + placebo) and will be evaluated at baseline, at completion of the treatment (12 sessions over 12 weeks), and again at 6 months and 12 months post-treatment.

NCT ID: NCT00261729 Completed - Clinical trials for Stress Disorders, Post-Traumatic

Prazosin vs. Paroxetine in Combat Stress Symptoms in OIF/OEF Returnees

Start date: July 2004
Phase: N/A
Study type: Interventional

Evaluate the efficacy and tolerability of the drug prazosin compared to placebo for combat stress-related nightmares, sleep disturbance and overall function in recently combat-exposed returnees from OIF and OEF. To evaluate the effects of the SSRI paroxetine on behavioral symptoms and overall function in this population.

NCT ID: NCT00260195 Completed - Depression Clinical Trials

A School Program for Children Exposed to Violence

Start date: July 2005
Phase: Phase 2
Study type: Interventional

This study will develop a program to help school children deal with violence-related trauma.

NCT ID: NCT00256477 Completed - Clinical trials for Posttraumatic Stress Disorder

A Controlled Breathing Course for Social & Emotional Health for Vietnam Veterans With Chronic PTSD-RCT

Start date: March 2005
Phase: Phase 1
Study type: Interventional

The main aim of this project is to evaluate the use of a specific Yoga technique of controlled breathing in Vietnam War Veterans with chronic posttraumatic stress disorder. This method is currently the subject of a United States grant application to formally test American War Veterans from Afghanistan and Iraq. Drs Gerbarg and Brown are collaborating with The Bay Pines Veterans Administration Medical Center in Florida to develop a study of this course for treatment of American veterans returning from Afghanistan and Iraq. Elements of this method have been used on a variety of populations. Whilst this is a multi-component intervention, it is postulated that the most active ingredient in the program is a specific Yoga breathing technique called Sudarshan Kriya (SK).

NCT ID: NCT00256464 Not yet recruiting - Depression Clinical Trials

Evaluation of a MCYI as Adjunct to Psychiatric Treatment for Vietnam Veterans With PTSD - RCT

Start date: June 2007
Phase: Phase 1
Study type: Interventional

The principal aim of this project is to conduct a Randomized Controlled Trial (RCT) to examine whether adding a twelve-session Multi-Component Yoga Intervention (MCYI) to the treatment regimen of Australian Vietnam Veterans suffering chronic Posttraumatic Stress Disorder (PTSD) leads to a significantly greater clinical improvement than conventional psychiatric treatment alone. Include 12 sessions with each session 3 hours duration- 4 days per week for 3 weeks i.e. total of 36 hours. The Multi-Component Yoga Intervention (MCYI) consisting of specific poses, breathing techniques, information about yoga techniques and practices, group processes, psychoeducation, relaxation procedures and meditation techniques in Vietnam War Veterans with chronic Posttraumatic Stress Disorder (PTSD) resistant to treatment has been developed. This project aims to evaluate MCYI through RCT method. It is hypothesised that Yoga augmentation will lead to: (1) reduced symptoms of PTSD and Depression; and (2) reduced alcohol intake. A secondary aim of the proposed RCT is to evaluate putative mediating variables. Benefits include that it is low cost and easy to apply. Done at home, non threatening and additional to standard psychiatric treatment for PTSD.

NCT ID: NCT00248261 Terminated - Clinical trials for Post-traumatic Stress Disorder

Ziprasidone and Sertraline in PTSD

Start date: November 2005
Phase:
Study type: Observational

Serotonin re-uptake inhibitors, such as sertraline, are the medication of choice in post-traumatic stress disorder. However, it takes several weeks before they ameliorate symptoms. Therefore, we will add ziprasidone (vs. placebo) medication during the first four weeks of sertraline in order to find out if this strategy accelerates symptomatic relief.

NCT ID: NCT00245232 Completed - Clinical trials for Post-Traumatic Stress Disorder

Cognitive Processing Therapy Versus Its Individual Components in the Treatment of Post-Traumatic Stress Disorder and Depression in Women Who Have Been Sexually Abused

Start date: August 2000
Phase: N/A
Study type: Interventional

This study will evaluate the effectiveness of cognitive processing therapy versus its individual components in treating women with post-traumatic stress disorder (PTSD) and depression brought on by sexual assault.

NCT ID: NCT00244335 Completed - Clinical trials for Stress Disorders, Post-Traumatic

Examining the Role of Negative Emotional States on Sedative Drug Use in Individuals With Post-Traumatic Stress Disorder

Start date: October 2000
Phase: Phase 1/Phase 2
Study type: Observational

Post-traumatic stress disorder (PTSD) is a serious illness, in which individuals often experience anxiety and stress. Some individuals with PTSD use drugs to alleviate emotional distress. This study will examine the role that negative emotional states play in sedative drug use among individuals with PTSD.

NCT ID: NCT00239772 Completed - Clinical trials for Post-Traumatic Stress Disorder

Cognitive Processing Therapy Versus Prolonged Exposure for Treating Women With Post-Traumatic Stress Disorder Brought on by Sexual Assault

Start date: May 1994
Phase: N/A
Study type: Interventional

This study will evaluate the effectiveness of cognitive processing therapy versus prolonged exposure therapy in treating women with post-traumatic stress disorder (PTSD) brought on by sexual assault.

NCT ID: NCT00237393 Completed - PTSD Clinical Trials

Quetiapine Treatment for Post-Traumatic Stress Disorder (PTSD)

PTSD
Start date: August 2003
Phase: Phase 4
Study type: Interventional

The purpose of the study is to determine if quetiapine is effective in the treatment of PTSD.