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Prostate Cancer clinical trials

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NCT ID: NCT02135653 Completed - Prostate Cancer Clinical Trials

A Feasibility Study Followed By A Randomized Phase II Study Of Yoga For Radiation Therapy Side Effects In Prostate Cancer

Start date: March 2013
Phase:
Study type: Observational

This study will ascertain the feasibility and effect of Eischens yoga interventions on radiation related fatigue, sexual dysfunction and urinary incontinence in stage I /II prostate cancer patients undergoing radiotherapy with photons and/or protons without prostatectomy. Subjects must be smoke free and have not taken regular yoga classes 6 months prior to enrollment. Subjects will participate in twice weekly yoga sessions for 8 weeks and complete 4 quality of life forms 5 times during study.

NCT ID: NCT02135484 Completed - Prostate Cancer Clinical Trials

Radium 223 in Castrate Resistant Prostate Cancer Bone Metastases

Start date: September 19, 2014
Phase: N/A
Study type: Interventional

The goal of this clinical research study is to learn more about how the study drug alpharadin (Radium-223) works in patients who have CPRC that has spread to the bone.

NCT ID: NCT02132975 Completed - Prostate Cancer Clinical Trials

Motorised Probe Holder Assisting Prostate Biopsies

PROSBOT-Apollo
Start date: May 2014
Phase: N/A
Study type: Interventional

Study, for the first time in clinical conditions, the potential contribution, in terms of accuracy, of the motorised probe holder during prostate biopsies.

NCT ID: NCT02131779 Completed - Prostate Cancer Clinical Trials

Men's Prostate Awareness Church Training

M-PACT
Start date: February 2012
Phase: N/A
Study type: Interventional

The objective of the Prostate Cancer Education in African American Churches project is to develop and evaluate a spiritually-based educational intervention for Informed Decision Making (IDM) for prostate cancer screening to be delivered to African American men in church settings.

NCT ID: NCT02131649 Completed - Prostate Cancer Clinical Trials

PET/MRI for Men Being Considered for Radiotherapy for Suspected Prostate Cancer Recurrence Post-Prostatectomy

PROPS
Start date: February 2015
Phase: N/A
Study type: Interventional

The PROPS trial is for men being considered for radiotherapy due to the suspicion that their prostate cancer has recurred following the surgical removal of their prostate (prostatectomy). This suspicion is based on rises seen on Prostate Specific Antigen (PSA) blood tests. Only men who demonstrate the absence of disease on standard imaging scans (Computed Tomography (CT) and bone scans) will be invited to participate. This study will be assessing if the imaging probe 18-F Fluorocholine (18F-FCH) used during Positron Emission Tomography (PET) and Magnetic Resonance Imaging (MRI) scans, can better predict who will benefit from radiotherapy by identifying the source of cancer recurrence. This will be determined by measuring the number of men who have disease identified outside of the prostate bed (the small pocket or depression where the prostate used to be) on their 18F-FCH PET scan. Since F-18-FCH has been shown to be more sensitive in detecting prostate cancer that may have spread into lymph nodes or bone, it may potentially identify areas of prostate cancer spread not seen with standard imaging.

NCT ID: NCT02130700 Completed - Prostate Cancer Clinical Trials

Oral VT-464 in Patients With Castration-Resistant Prostate Cancer Previously Treated With Enzalutamide, Androgen Receptor Positive Triple-Negative Breast Cancer Patients, and Men With ER Positive Breast Cancer

Start date: April 2014
Phase: Phase 2
Study type: Interventional

The goal of this clinical study is to determine the safety and efficacy of VT-464, a lyase-selective inhibitor of CYP17, in patients with castration-resistant prostate cancer (CRPC) who have been previously treated with Enzalutamide, Androgen Receptor Positive Triple-Negative Breast Cancer Patients, and Men with ER positive Breast Cancer.

NCT ID: NCT02126319 Completed - Prostate Cancer Clinical Trials

Facilitating Participation in a Prostate Cancer Risk Assessment Program

Start date: October 1998
Phase: N/A
Study type: Interventional

The purpose of this study was to examine whether a cognitive-affective preparation was more beneficial, in general, and more specifically for certain subgroups, such as African-American men and individuals with high monitoring style.

NCT ID: NCT02125175 Completed - Prostate Cancer Clinical Trials

BIOPROP20: Biologically Optimised IMRT for Prostate Radiotherapy Hypofractionated Radiotherapy With Intra-prostatic Boosts to Tumour Nodules in Men With Intermediate and High Risk Prostate Cancer

BIOPROP20
Start date: January 2014
Phase: N/A
Study type: Interventional

High dose radiotherapy is a very effective treatment for prostate cancer. However, there is an increased risk of side effects compared to lower dose radiotherapy. This study will investigate the use of dose painting radiotherapy. Dose painting radiotherapy administers a high dose of radiotherapy to areas of cancer inside the prostate and a lower (standard) dose to the rest of the prostate. This may improve control of the cancer without increasing the side effects. The radiotherapy is given in 20 doses, called fractions.

NCT ID: NCT02125084 Completed - Prostate Cancer Clinical Trials

Enzalutamide Plus Everolimus in Men With Metastatic Castrate-Resistant Prostate Cancer

Start date: October 2014
Phase: Phase 1
Study type: Interventional

The purpose of this study is to determine the safety and efficacy of a novel combination of agents, enzalutamide and everolimus, for the treatment of patients with metastatic castrate-resistant prostate cancer who have never received prior chemotherapy, or who have previously received docetaxel chemotherapy and have progressive disease.

NCT ID: NCT02124668 Completed - Prostate Cancer Clinical Trials

A Study to Monitor the Safety of Enzalutamide in Patients With Progressive Castration-Resistant Prostate Cancer Previously Treated With Docetaxel-Based Chemotherapy

Start date: September 23, 2014
Phase: Phase 2
Study type: Interventional

The purpose of this study is to monitor the safety of enzalutamide in patients with progressive castration-resistant prostate cancer previously treated with docetaxel-based chemotherapy.