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Pain, Postoperative clinical trials

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NCT ID: NCT04275258 Recruiting - Pain, Postoperative Clinical Trials

Collaborative Opioid Taper After Trauma: Preventing Opioid Misuse and Opioid Use Disorder

Start date: June 1, 2020
Phase: N/A
Study type: Interventional

The investigators will enroll 100 participants using a randomized control trial design to implement and evaluate an individualized opioid taper program supporting rural Primary Care Physicians (PCPs) caring for patients with moderate to severe trauma discharged on opioids. This study will link a trauma center Physician Assistant (PA) with rural PCPs to facilitate pain care and the individualized opioid taper. The investigators seek to improve patient's pain and opioid outcomes and support the PCPs who assume care for these complex patients after hospital discharge. Our long term goal is to provide a service that will help trauma patients as they go back into primary care and into pain- and opioid-free living.

NCT ID: NCT04274530 Recruiting - Pain, Postoperative Clinical Trials

Cognitive Behavioural Therapy to Optimize Post-Operative Recovery Trial

COPE
Start date: January 25, 2021
Phase: N/A
Study type: Interventional

Psychological factors such as stress, distress, anxiety, depression, and poor coping strategies may be associated with ongoing pain following injuries such as fractures. To study this relationship, patients will undergo cognitive behavioural therapy (CBT) which is designed to modify such thoughts with the goal of reducing ongoing pain and improving quality of life. The goal of this study is to determine if CBT, versus usual care, reduces the prevalence of moderate to severe persistent post-surgical pain (PPSP) over 12-months post-fracture in patients with an open or closed fracture of the appendicular skeleton, treated with internal fixation.

NCT ID: NCT04259476 Recruiting - Clinical trials for for Post-operative Pain Relief in Spine Surgeries

Low Dose Perioperative Ketamine Infusion and it's Effect on Postoperative Pain Score, Sedation Score and Narcotic Consumption in Patients Undergoing Spine Surgery: A Prospective Randomized Double Blind Control Trial.

Start date: January 1, 2020
Phase: Phase 1
Study type: Interventional

Low dose perioperative ketamine infusion and it's effect on postoperative pain score, sedation score and narcotic consumption in patients undergoing spine surgery: A prospective randomized double blind control trial.

NCT ID: NCT04259333 Recruiting - Pain, Postoperative Clinical Trials

Celecoxib vs. Acetaminophen/Codeine/Caffeine for Post-operative Analgesia in Rhinoplasty.

Start date: March 1, 2020
Phase: Phase 4
Study type: Interventional

The primary aim of this study is to evaluate whether celecoxib (CELEBREX) is equivalent to acetaminophen-codeine-caffeine (TYLENOL# 3) for the management of pain after primary elective open septorhinoplasty with osteotomies. Secondary objectives include comparison of adverse medication effects and complications (e.g., bleeding events and bruising) that occur postoperatively. Half of the study participants will receive celecoxib, and half will receive acetaminophen-codeine-caffeine. We hypothesize that both interventions will exhibit no difference in pain control or postoperative bleeding, but that participants taking CELEBREX will experience less medication-related side effects and less bruising postoperatively.

NCT ID: NCT04258241 Recruiting - Clinical trials for Primary Total Knee Arthroplasty

The Efficacy of Local Infiltration Analgesia for Postoperative Pain Management After Total Knee Arthroplasty

Start date: March 6, 2020
Phase: N/A
Study type: Interventional

This prospective, double-blinded, randomized controlled study evaluates the effects of peripheral nerve blocks with and without local infiltration analgesia for postoperative pain management after primary total knee arthroplasty. There are no any studies that show the demand for local infiltration analgesia when together peripheral nerve blocks are performed. Patients undergoing primary total knee arthroplasty will be randomly assigned to receive local infiltration analgesia with or without (placebo group) local anesthetic. All patients will receive peripheral nerve blocks for postoperative analgesia: femoral triangle and distal adductor canal blocks. Comparison of these two groups of patients will be based on the effects on postoperative pain control, the extent of motor blockade, the ability of early leg motion and ambulation, patients satisfaction rates over the time of clinical recovery. Consequently, the investigators hypothesized that peripheral nerve blocks (femoral triangle and distal adductor canal blocks) with and without local infiltration analgesia provide similar postoperative pain relieving effects and the ability of early mobilization after total knee arthroplasty.

NCT ID: NCT04256057 Recruiting - Clinical trials for the Effect of Intraoperative Magnesium Infusion on Postoperative Cognitive Functions in Adult Patients After Elective Pelvi-abdominal Surgeries

Effect of Intraoperative Magnesium Infusion on Postoperative Pain and Cognitive Function

Start date: March 15, 2020
Phase: Early Phase 1
Study type: Interventional

The aimof this study is to observe the effect of intraoperative magnesium infusion on peri-operative pain and postoperative cognitive functions in adult patients after elective pelvi-abdominal surgeries.

NCT ID: NCT04250974 Recruiting - Clinical trials for Postoperative Pain Relief

Evaluaing the Effects of Electroacupuncture for Postoperative Pain Relief in Patients With Distal Radius Fracture

Start date: December 5, 2019
Phase: N/A
Study type: Interventional

Single-blinded, randomized preliminary study evaluating the effects of electroacupuncture for postoperative pain relief in patients with distal radius fracture. Distal radius fracture is extremely common, and it is about 10% of all fractures in the human body. Therefore, the distal radius is the most frequently fractured part of the upper limbs of the human body. Once the fracture occurs, internal fixation is the main surgical procedure. The postoperative analgesic method is generally oral or injection analgesic. In recent years, electroacupuncture(EA) has been widely used to relieve pain after surgery, and many studies have confirmed that it is effective. However, there is no evaluation of analgesic efficacy after the surgery of distal radius fracture. Therefore, it is hoped that the efficacy of EA for analgesia after the surgery of distal radius fracture is demonstrated by this study. And, the investigators also hope the investigators can reduce the use of painkillers through EA. Methods: It is expected that 30 patients will be randomly assigned to the following groups: EA group,EA at points; non-point group, EA at non-points, control group without EA 1. EA group:EA at points after surgery 2. non-point group: EA at non-points after surgery 3. Control group: no EA

NCT ID: NCT04250519 Recruiting - Clinical trials for Root Canal Infection

Evaluation of Post Operative Pain in Retreatment of Molars Using Different Irrigant

Start date: February 3, 2020
Phase: Phase 1
Study type: Interventional

This study evaluates the efficacy of dexamethasone as a intracanal irrigant along with sodium hypochlorite 1% and 5.25% concentrations in post treatment pain for molar root canal retreatment.

NCT ID: NCT04250272 Recruiting - Lung Cancer Clinical Trials

Serratus Anterior Plane Block Versus Intercostal Nerve Block for Postoperative Analgesia

Start date: August 16, 2019
Phase: N/A
Study type: Interventional

A prospective randomized controlled study was undertaken to compare the postoperative analgesic effect between ultrasound-guided serratus anterior plane block and intercostal nerve block after video-assisted thoracoscopic lobectomy.

NCT ID: NCT04245280 Recruiting - Postoperative Pain Clinical Trials

Effectiveness of PENG Block Combined to LFCN Block on the Quality of Recovery After Total Hip Replacement

PENG
Start date: May 4, 2021
Phase: N/A
Study type: Interventional

The main objective of this study is to evaluate the effectiveness of the association of PENG and LFCN blocks on the quality of recovery 24 hours after total hip replacement surgery.