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Pain, Postoperative clinical trials

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NCT ID: NCT04840654 Recruiting - Postoperative Pain Clinical Trials

Pudendal vs Caudal Block for Pediatric Penile Surgery

Start date: May 1, 2021
Phase: N/A
Study type: Interventional

The study will compare recovery profile in children receiving pudendal blocks vs caudal analgesia for ambulatory circumcision or hypospadias repair in children between 6 months and 2 years. The subjects of the study will be randomized to receive either a caudal or a pudendal block.

NCT ID: NCT04837014 Recruiting - Pain, Postoperative Clinical Trials

Eliminating Narcotic Prescriptions From Outpatient Minimally Invasive Gynecologic Surgery

eNARCOS
Start date: July 4, 2022
Phase: N/A
Study type: Interventional

Laparoscopic gynecologic surgeries are generally very well tolerated procedures, and patients are able to go home on the same day, with a prescription for pain control. There is currently a very wide range of prescription practice within the gynecology community in regards to opioids following surgery, and patients are going home with anything from zero to 5 or even 20 tabs of narcotics. Aside from negative side effect of opioids (like nausea/vomiting, dizziness, constipation, and possibly addiction), unnecessary opioid prescriptions and excess unused narcotics is one of the major contributors to narcotic abuse in the community, worsening an ongoing nationwide opioid crisis. Although most patients report low pain level following these kinds of procedure, there are no current standard prescriptions after gynecologic laparoscopy. In an effort to standardize discharge prescriptions following gynecologic laparoscopy, this study aims to find an optimal regimen for pain control in the post-operative period following laparoscopic gynecologic surgery. There will be 2 standardized set of discharge prescriptions to which patient will be randomized; both containing multimodal medications for pain control. Pain control, and patients satisfaction will be measured in the first post-operative week.

NCT ID: NCT04820400 Recruiting - Pain, Postoperative Clinical Trials

Reducing Pain and Anxiety During Dressing Changes After Burn Surgery Using Virtual Reality

BURN-360
Start date: March 24, 2021
Phase: N/A
Study type: Interventional

Burn injury and its treatment is an intensely painful experience. Most severely injured patients require numerous dressing changes and skin grafting procedures (removing skin from healthy part of the body and moving it to damaged area of the body). This procedure cause extensive pain and anxiety and many patients can become dependent on pain killers during their hospital stay and throughout rehabilitation. This can delay reintegration into society and increase the chance of opioid dependence. An effective pain management plan plays a large role in patient recovery. In addition to the physical pain experienced by these patients, burn injury is an intensely stressful and emotional life experience. This study will use a non-drug approach to reduce pain and extensive use of pain killers (opioids) during dressing changes. In particular, the study will use an immersive (allows to experience computer-generated environment as a real world) Virtual reality (VR) distraction tool during dressing change after skin graft surgery. Individuals who will decide to participate in this study will be asked to wear headgear to view immersive 360 videos specially designed by the study team. Before and after this exposure participants will be asked to complete a measurement of their anxiety level (VAS) and rate their pain. This study will help to determine if using VR as a distraction tool during painful dressing changes will reduce pain and anxiety, and therefore opioid medications requirements, and will rely on participants experience and adapt VR videos according to participants' response.

NCT ID: NCT04804761 Recruiting - Clinical trials for Symptomatic Irreversible Pulpitis (SIP)

The Effect of Electroacupuncture (EA) on the Success of Inferior Alveolar Nerve Block (IANB) and Post-operative Pain Relief in Mandibular Molar With Symptomatic Irreversible Pulpitis (SIP) Among Malaysians: A Study Protocol for Randomized Double-Blinded Clinical Pilot Study

Start date: January 1, 2023
Phase: N/A
Study type: Interventional

Acupuncture is recognized for its pain relief effect. Electroacupuncture(EA) is a form of acupuncture where electric current is passed between pairs of acupuncture needles in order to achieve therapeutic effect. However, there are significantly low number of studies which have discussed the effect of electroacupuncture on dental treatment. Symptomatic irreversible pulpitis is a common condition among dental patients. The success rate of inferior alveolar nerve block before commencing the endodontic treatment of a tooth diagnosed with SIP is reported to be relatively as low as 25%. The aim of this study is to determine the effect of electroacupuncture on the success rate of inferior alveolar nerve block and post-operative pain relief for symptomatic irreversible pulpitis among Malaysians.

NCT ID: NCT04791943 Recruiting - Pain, Postoperative Clinical Trials

Preoperative Melatonin to Decrease Analgesia Usage After Third Molar Surgery

Start date: May 12, 2021
Phase: Phase 2
Study type: Interventional

The purpose of the study is to assess if melatonin given for three nights before wisdom tooth surgery decreases post-operative pain and pain medication consumption. Patients will receive either melatonin or a placebo for three nights prior to surgery and we will measure pre-operative anxiety, preoperative sleep quality, post op pain medication consumption, post op pain scores, and blood values.

NCT ID: NCT04782310 Recruiting - Postoperative Pain Clinical Trials

Duloxetine vs Pregabalin for Thoracotomy Pain

Start date: March 10, 2021
Phase: Phase 4
Study type: Interventional

This study investigates the effects of preoperative use of oral combination of duloxetine and Pregabalin in comparison with preoperative oral Pregabalin only in treatment of acute postoperative and prevention of chronic pain following thoracotomy surgeries.

NCT ID: NCT04767399 Recruiting - Post Operative Pain Clinical Trials

Comparison of Postoperative Pain After Instrumentation in Different Visits With Different Single File Systems.

Start date: September 10, 2020
Phase: N/A
Study type: Interventional

Comparison of Postoperative Pain after Root Canal preparation, in Single and Multiple Visits, with Reciprocating and Rotary Single-File Systems: A Randomized Clinical Trial. Aim:1. Compare between the postoperative pain after root canal preparation, in single and multiple visits. 2. To assess the influence of reciprocating and rotary single-file systems instrumentation on post-operative pain.

NCT ID: NCT04764916 Recruiting - Pain, Postoperative Clinical Trials

Evaluation of Exparel Adductor Canal Field Block for Pain Control After ACL Reconstruction

Start date: February 16, 2021
Phase: Phase 3
Study type: Interventional

This is a prospective, randomized study for adult patients presenting to the Carilion Clinic Institute of Orthopedics and Neurosurgery. Patients undergoing isolated ACL reconstruction will be eligible for inclusion. All patients will receive an adductor canal block (either with bupivacaine or Exparel. Patients will be given a pain diary for self-report of pill counts, pain scores, block duration, and pain control satisfaction). Pill counts and pain scores will also be taken by a team member at two and six-week post-operative visits. Primary outcomes include opioid requirements and pain scores.

NCT ID: NCT04764825 Recruiting - Pain, Postoperative Clinical Trials

Methadone for Spinal Fusion Surgery.

METASPINE
Start date: February 26, 2021
Phase: Phase 4
Study type: Interventional

A prospective double-blind, randomized controlled trial investigating the effect of a single-dose of intraoperative methadone in patients undergoing spinal fusion.

NCT ID: NCT04751812 Recruiting - Pain, Postoperative Clinical Trials

Venous Cannulation Pain to Guide Choice of Anesthetic Method

Start date: March 1, 2022
Phase: N/A
Study type: Interventional

The investigators have recently shown that pain associated with peripheral venous cannulation can be used to predict the risk of postoperative pain, where patients grading their pain associated with venous cannulation (VCP) above 2.0 VAS units had 3.4 times higher risk of moderate or severe postoperative pain after laparoscopic cholecystectomy and 1.7 times higher risk in a mixed group of patients and surgeries. The aim of this study is to investigate whether pain sensitivity measurements using VCP can be used to choose anesthesia treatment protocol with the aim to lower acute postoperative pain in those with high risk. In patients with low risk we aim to lower the amount of opioids given.