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Pain, Postoperative clinical trials

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NCT ID: NCT01030029 Completed - Acupuncture Clinical Trials

Auricular Acupuncture in Postoperative Pain

Start date: January 2006
Phase: Phase 4
Study type: Interventional

The effect of acupuncture for postoperative pain control remains controversial. We therefore studied the effects of electrical auricular acupuncture (AA) on postoperative opioid consumption in a randomized, patient-blinded clinical trial. 40 female patients undergoing laparoscopy were included. Anaesthetized patients were randomly assigned to receive AA (shen men, thalamus and one segmental organ-specific point) or electrodes and electrical stimulation for 72 hours. Postoperatively patients received 1 g paracetamol every 6 hours and additional piritramide on demand. A blinded observer obtained the doses of piritramide and the visual analogue pain scores (VAS) at 0, 2, 24, 48, and 72 hours. It was the aim of our study to find out, whether auricular acupuncture reduces postoperative pain.

NCT ID: NCT01025102 Completed - Postoperative Pain Clinical Trials

The Addition of Sufentanil Interscalene Block in Shoulder Surgery

Start date: January 2010
Phase: Phase 3
Study type: Interventional

The purpose of this study is to compare the effects and side effects of interscale block performed with Naropin 0.1% cum sufentanil or Naropin 0.1% in shoulder surgery.

NCT ID: NCT01024348 Not yet recruiting - Postoperative Pain Clinical Trials

Safety and Effectiveness of Tramadex-OD After Knee Arthroscopy

Start date: December 2009
Phase: N/A
Study type: Interventional

Extended-release tramadol is indicated for the management of moderate to severe pain in adults who require around-the-clock treatment. It provides an extended duration of action, more constant plasma concentrations, a reduced dosing frequency, and the potential for improved compliance and therapeutic outcomes. The present study was designed to evaluate the safety and effectiveness of this medication in the treatment of early postoperative pain after knee arthroscopy.

NCT ID: NCT01022528 Completed - Postoperative Pain Clinical Trials

Analgesic Effect of Preoperative Dexamethasone in Gynecological Laparotomies - a Dose-ranging Study

Start date: March 2009
Phase: N/A
Study type: Interventional

The objective of the study is to examine the effect of the addition of intravenous dexamethasone 1.5 hours prior to induction of anesthesia on the post-operative opioid consumption, pain scores, fatigue, and recovery in patients undergoing gynecological surgery with laparotomy under general anesthesia. This is a dose finding study with two different doses (0.1 mg/kg vs. 0.2 mg/kg) of dexamethasone to find out the optimal efficacious dose of dexamethasone with minimal side effects. Dexamethasone has anti-inflammatory, immunomodulatory, and analgesic effects; and is superior to placebo in providing post-operative pain control, lower analgesic consumption, prevention of postoperative nausea and vomiting, lesser post-operative fatigue, and better recovery profile. No dose response study has been done. The investigators hypothesize that a higher dose of dexamethasone may have an incremental beneficial effect.

NCT ID: NCT01018277 Completed - Pain, Postoperative Clinical Trials

Effect of Mobilization on Acute Postoperative Pain and Nociceptive Function

Start date: December 2009
Phase: Phase 4
Study type: Observational

Aim of the present study is twofold. - First we want to evaluate the effect of mobilization on acute postoperative pain - Second to test weather chances in pain sensitivity are occurring following surgery and mobilization after total knee arthroplasty

NCT ID: NCT01016808 Completed - Clinical trials for Moderate to Severe Postoperative Pain

Comparison of the Efficacy and Safety of Q8003 Versus Its Individual Components in Bunionectomy Patients

Start date: December 2009
Phase: Phase 3
Study type: Interventional

This is a randomized, double-blind, multicenter, fixed dose factorial study of Q8003 12 mg/8 mg versus its individual morphine sulfate and oxycodone hydrochloride components for the management of acute moderate to severe postoperative pain following bunionectomy surgery.

NCT ID: NCT01015235 Completed - Pain, Postoperative Clinical Trials

Safety and Efficacy Study of KAI-1678 to Treat Subjects With Postoperative Pain

Start date: December 2008
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine whether KAI-1678 is effective in the treatment of postoperative pain following total hip or total knee replacement.

NCT ID: NCT01015053 Completed - Clinical trials for Pediatric Postoperative Pain

Postoperative Pain After Pediatric Umbilical Hernia Repair

Start date: November 2009
Phase: N/A
Study type: Interventional

The purpose of this study is to compare the use of ultrasound-guided bilateral rectus sheath blocks to local infiltration of anesthetic agent in the surgical wound in a pediatric population of patients undergoing umbilical hernia repair.

NCT ID: NCT01014520 Recruiting - Clinical trials for Intervertebral Disc Displacement

Efficacy of Gabapentin or Amitriptyline to Reduce Postoperative Pain After Lumbar Laminectomy and Diskectomy

Start date: May 2009
Phase: Phase 2
Study type: Interventional

The hypothesis of this study is that Gabapentin or Amitriptyline has no role in preemptive analgesia to reduce postoperative pain after lumbar diskectomies.

NCT ID: NCT01012232 Completed - Postoperative Pain Clinical Trials

Local Anesthetic in Total Knee Arthroplasty (TKA): Volume Versus Concentration

Start date: June 2009
Phase: Phase 4
Study type: Interventional

In a randomized, double-blind, cross-over trial, 48 patients scheduled for total knee arthroplasty with placement of an intracapsular catheter will be randomized to receive bolus injection of ropivacaine in high volume/low concentration (20 ml, 5 mg/mL) or low volume/high concentration (10 mL, 10 mg/mL) 6 and 24 hours postoperatively, and pain will be assessed at rest and with mobilization for 2 hours after injections.