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Pain, Postoperative clinical trials

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NCT ID: NCT03117062 Completed - Postoperative Pain Clinical Trials

Occlusal Reduction and Postoperative Pain

Start date: September 2014
Phase: N/A
Study type: Interventional

The purpose of this randomized clinical study was to evaluate the impact of occlusal reduction on the incidences of post-instrumentation and post-obturation pain. Forty four patients were included in this study. Inclusion criteria were posterior mandibular teeth having symptomatic irreversible pulpitis and symptomatic apical periodontitis. Patients were randomized into two equal groups. In the intervention group the functional and nonfunctional cusps were reduced until absence of contact was confirmed, while in the control group the occlusal surfaces were left intact. Standard endodontic treatment was performed in two visits using rotary nickel titanium files for shaping, 2.5% sodium hypochlorite for cleaning and lateral condensation technique with resin sealer for obturation. Pain was assessed preoperatively, then after 6, 12, 24 and 48 hours following instrumentation, then after 6 and 12 hours following obturation. Visual Analogue Scale (VAS) was used as the primary outcome measure. Patients were given a placebo to be administrated in case of severe pain and ibuprofen 400mg was prescribed in case of persistent pain.

NCT ID: NCT03114449 Completed - Postoperative Pain Clinical Trials

Auricular Acupuncture vs. Sham Procedure for Pain Control After Knee Arthroplasty

AA_K-TEP
Start date: October 2012
Phase: N/A
Study type: Interventional

Aim of the study To investigate whether auricular acupuncture (AA) will reduce postoperative pain and analgesic requirement in comparison with sham AA in patients after elective knee arthroplasty Design Prospective randomized controlled blinded clinical trial Participants: - Patients < 80 und > 50 years old - scheduled for knee arthroplasty under general anesthesia with < 120 minutes duration - Without previous opioid medication - Able to give informed consent Outcome measures - Postoperative analgesic requirement - Incidence of side effects - Physiological parameters

NCT ID: NCT03112915 Recruiting - Postoperative Pain Clinical Trials

Comparison of the Quadratus Lumborum Block With the Transversus Abdominis Plan Block

Start date: April 20, 2017
Phase: N/A
Study type: Interventional

In this study, investigators aimed to compare the Quadratus Lumborum Block and the Transversus Abdominis Plan Block for postoperative pain control after laparoscopic cholecystectomy

NCT ID: NCT03111381 Completed - Pain, Postoperative Clinical Trials

Toradol to Reduce Ureteroscopic Symptoms Trial

TRUST
Start date: August 1, 2017
Phase: Phase 2
Study type: Interventional

Double blinded randomized controlled clinical trial to assess the impact of intraoperative Toradol on post-operative pain scores for patients undergoing ureteroscopy for urinary stone management.

NCT ID: NCT03107702 Enrolling by invitation - POSTOPERATIVE PAIN Clinical Trials

Melatonin Level and Postoperative Analgesia Consumption in Bariatric Surgery Patients.

Start date: March 29, 2017
Phase: N/A
Study type: Observational

Bariatric surgical procedures are associated with low short-term mortality and may be associated with long-term reductions in all-cause, cardiovascular, and cancer-related mortality. This surgeries are major surgeries include risk of mortality still. Melatonin is a hormone secreted from the pineal gland. Melatonin is an antioxidant, antinociceptive, hypnotic, anticonvulsant, neuroprotective, anxiolytic, sedative and analgesic. Melatonin is neurohormone with the profile of a novel hypnotic-anesthetic agent. The purpose of this study is to investigate the preoperative, perioperative and postoperative melatonin levels in bariatric surgery under general anesthesia and to investigate the relationship between melatonin level and analgesia requirement.

NCT ID: NCT03106818 Completed - Postoperative Pain Clinical Trials

Postoperative Pain Alleviation in Open Heart Surgery

Start date: July 2016
Phase: N/A
Study type: Interventional

Effective pain relief after cardiac surgery has assumed importance with the introduction of fast track discharge protocols that requires early weaning from mechanical ventilation. Inadequate pain control reduces the capacity to cough, mobility, increases the frequency of atelectasis, and prolongs recovery. Infiltration of local anesthetics near the surgical wound has shown to improve early postoperative pain in various surgical procedures. Magnesium is the fourth most plentiful cation in our body. It has antinociceptive effects in animal and human models of pain.

NCT ID: NCT03105518 Active, not recruiting - Postoperative Pain Clinical Trials

Predictors of Postoperative Pain Following Oocyte Retrieval for Assisted Reproduction

Start date: March 1, 2011
Phase: Phase 4
Study type: Interventional

The central objective of this study will be to evaluate the relationship between estrogen levels and the pain following oocyte retrieval in women undergoing in vitro fertilization.

NCT ID: NCT03102515 Completed - Postoperative Pain Clinical Trials

Transversus Abdominis Plane Block vs Continuous Infiltration Wound Catheter for Analgesia After Caesarean Section

TAP-CAT
Start date: May 29, 2016
Phase: Phase 4
Study type: Interventional

Analgesia following surgery associates different intra-venous or oral analgesic drugs and sometimes opioids. To reduce opioid consumption, loco-regional anaesthesia might be administered as a complement. In the specific context of caesarean sections, pain control is mandatory to enable the mother to take care of her offspring and shorten their hospital stay. This intervention is mainly performed under neuraxial anaesthesia (spinal or epidural), enabling the injection of morphine in the subdural or epidural space, as part of a multimodal analgesia regimen. Studies have evaluated continuous wound infiltration catheters (CIC) and ultrasound-guided (UGD) transabdominis plane (TAP) block, and both techniques and both techniques reduce postoperative morphine consumption. Recent studies have compared the two techniques and found conflicting results. Furthermore, they did not consider caesarean section performed under epidural analgesia, with a different neuraxial injection site, neither did they compared pain after postoperative day 2. Consequently, the aim of this study was to compare resting and standing pain up to postoperative day 3 after caesarean section performed under spinal or epidural anaesthesia and receiving either USG-TAP block or CIC. Baseline hypothesis was that the continuous infiltration provided a better analgesia at day 2.

NCT ID: NCT03102333 Completed - Pain, Postoperative Clinical Trials

Comparison: Constant-rate Infusion Plus Demanding Dosing VS Variable-rate Feedback Infusion Plus Demanding Dosing

Start date: December 30, 2016
Phase: N/A
Study type: Interventional

In the case of the newlys developed PCA, the infusion rate is increased according to the patient's need for bolus button, so that the pain can be controlled more efficiently.

NCT ID: NCT03099720 Completed - Pain, Postoperative Clinical Trials

Local Analgesia to Prevent Pain in Patient Undergoing Removal of the Uterus Through Vaginal Route

Start date: April 4, 2017
Phase: Phase 4
Study type: Interventional

Following a hysterectomy, women tend to experience high levels of pain, and many require strong pain killers after the procedure. Ropivacaine is a local anaesthetic drug (injectable numbing medication) which works by blocking pain signals. The aim of this study is to find out whether injections of ropivacaine during surgery can help provide effective pain relief after surgery.Women aged between 45 and 70 who are having a vaginal hysterectomy can participate in the trial. Participants are randomly allocated to one of two groups. Those in the first group are given injections of ropivacaine at the site of the wound and in the peritoneum (space in the body that holds the organs in the abdomen) and those in the second group are given injections of a saline fluid in the same places that offers no pain relief before the end of their surgery. Participants in both groups are then regularly asked to rate their pain levels up to 24 hours after surgery. In addition, the pain killers they receive and length of hospital stay are recorded. There is a chance that the participants who receive the ropivacaine will benefit from lower pain levels after surgery. There are no notable risks of participating.