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Overweight clinical trials

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NCT ID: NCT03273361 Completed - Obesity Clinical Trials

Desk Cycling Work Performance Evaluation

Start date: August 1, 2016
Phase: N/A
Study type: Interventional

This lab study is evaluating the feasibility of accomplishing productive office work while simultaneously pedaling a compact desk-based cycling device.

NCT ID: NCT03272867 Completed - Healthy Volunteers Clinical Trials

Effect of an Anti-ageing Supplement on Oxidative Stress

PromAge
Start date: December 2014
Phase: N/A
Study type: Interventional

This pilot study serves to investigate whether ProManna intake leads to any changes in baseline levels for oxidative stress markers. In addition, biomarker responses following oxidative stress challenge tests will be assessed in subjects taking ProManna versus placebo supplements.

NCT ID: NCT03270423 Completed - Obesity, Adolescent Clinical Trials

PathMate2: The Impact of Health Information System Services on the Effects of Therapy in Overweight Teenagers

PM2
Start date: January 30, 2017
Phase: N/A
Study type: Interventional

Randomised controlled trial in overweight adolescents using a health App.

NCT ID: NCT03264248 Completed - Depression Clinical Trials

Daily Weight Feedback for Wheelchair Users to Promote Weight Loss

Start date: July 1, 2017
Phase: N/A
Study type: Interventional

The goals of the proposed study are to test the usability, feasibility and preliminary efficacy of the E-Scale with wheelchair users. The E-scale was developed as a weight monitoring technology for wheelchair users. Up to fifteen overweight or obese wheelchair users will be enrolled in a 13 week study that includes standard behavioral treatment (SBT) for weight loss, which focuses on diet, physical activity, and behavioral strategies (e.g., goal setting, self-monitoring) to support lifestyle changes specifically for people with mobility impairments. The subjects will also be provided the E-scale to track their weight daily. The outcome measure include usefulness (subjective feedback from a survey about the program/E-scale), feasibility (accuracy and repeatable measurements from the E-scale) and efficacy (improvements in weight and other measures of health) of the weight loss program coupled with the E-scale at the end of 13 weeks. The primary hypothesis is that the E-scale coupled with the weight loss intervention will result in significant improvements in weight, abdominal girth, body fat percentage, and the Center for Epidemiologic Studies Depression Scale (CES-D).The results may inform the refinement of this technology to increase its applicability for wheelchair users to independently monitor their weight in their own homes while attempting to lose weight.

NCT ID: NCT03261882 Completed - Clinical trials for Overweight and Obesity

Loss of a Healthy Weight Advantage Among Mexican-American Children

Start date: June 1, 2016
Phase: N/A
Study type: Observational

Although research indicates foreign-born Mexican-Americans possess a healthy weight advantage relative to U.S.-born Mexican-Americans, patterns are less clear for children and may be changing over time. The objective of this study was to examine whether the relationship between nativity and overweight/obesity has changed over time among Mexican-American children and to investigate the implications of this pattern on overweight/obesity disparities relative to non-Hispanic Whites. Using cross-sectional data from Mexican-Americans and non-Hispanic white children ages 4-17 years participating in the National Health and Nutrition Examination Surveys (1988-1994 (N=4,718) and 2005-2014 (N=7,269), the investigators used log-binomial regression to calculate prevalence ratios (PR) of overweight/obesity by nativity status adjusting for age, sex, householder marital status, householder education, survey period and a nativity by survey period interaction. The investigators also tested another covariate-adjusted model with a 3-level ethnicity-nativity variable that included Whites and an ethnicity-nativity by survey period interaction.

NCT ID: NCT03261453 Completed - Obesity Clinical Trials

THE ENLIGHTEN STUDY

Start date: February 1, 2018
Phase: N/A
Study type: Interventional

The primary objective of this study is to demonstrate the safety and efficacy of the Elipse Gastric Balloon System for the treatment of obese adults.

NCT ID: NCT03260114 Completed - Obesity Clinical Trials

Personal Activity Intelligence and Body Weight

Start date: August 24, 2017
Phase: N/A
Study type: Interventional

Physical activity is one of the key strategies used by public health agencies to combat the growing burden of obesity and non-communicable diseases. Adults around the world are recommended to engage in at least 150 minutes of moderate or 75 minutes of vigorous intensity activity per week, or a combination of moderate or vigorous activity that results in approximately the same total energy expenditure. However, majority of the population does not meet the physical activity recommendation. As barriers to physical activity, people mostly cite lack of time, self-motivation and confidence in the ability to be physically active. Cardiac Exercise Research Group (CERG) at Faculty of Medicine and Health Sciences at Norwegian University of Science and Technology recently developed Personal Activity Intelligence (PAI). PAI is a result of research based on the HUNT study where more than 60 000 individuals has been monitored over a period of more than 20 years. The goal is to make PAI the new world standard of activity tracking. PAI is an individual metric that makes sense of measured heart rate data, and significantly reduces the risk of lifestyle related diseases. The purpose of the study is to obtain new knowledge about how the use of PAI is related to body weight.

NCT ID: NCT03258203 Completed - Clinical trials for Overweight and Obesity

Gene-Environment Interaction and Precision Nutrition on Adiposity, Glycemic, Lipids Changes, and Bone Health

Start date: September 2003
Phase: N/A
Study type: Interventional

The purpose of this study is to test the interactions between the genes and diet interventions varying in macronutrient intake on glycemic, waist circumference, body weight, visceral fat and lipids changes. In the POUNDS LOST, all of the 811 participants DNA was extracted from the buffy coat fraction of centrifuged blood using the QIAmp blood kit (Qiagen, Chatsworth, CA). Single nucleotide polymorphisms were genotyped using the OpenArray™ SNP genotyping system (BioTrove, Woburn, MA). The study is only accepting participants in the Boston, Massachusetts or Baton Rouge, Louisiana area. For further enrollment information in Boston or Baton Rouge, see Eligibility Criteria or Design Narrative. Besides, the investigators integrated novel pathway analyses in large cohorts and comprehensive genetic analyses on long-term weight loss and mechanisms in randomized diet intervention trials would provide very important evidence to unravel the etiology of obesity, and have significant public health and clinical implications. Establishing relationship between genetic variants and diets in determining weight change will help identify individuals at high risk for obesity especially when adherent to specific diet.

NCT ID: NCT03257085 Completed - Clinical trials for Cardiometabolic Risk

CALIBER Phase 1: A Pilot Study in Normal-weight and Overweight Adults.

CALIBER
Start date: March 9, 2017
Phase: N/A
Study type: Interventional

Pilot study to compare the impact of following a low-carbohydrate, high-fat diet versus following a high-carbohydrates, moderate-fat diet (UK dietary guidelines) on cardiometabolic risk markers and associated behaviours in a normal-weight and overweight adult population.

NCT ID: NCT03256292 Completed - Aging Clinical Trials

Long-term Lifestyle Change and Testosterone Replacement

LITE
Start date: August 21, 2017
Phase:
Study type: Observational

Older hypogonadal obese veterans previously participated in a 6 month lifestyle change (diet-induced weight loss and exercise) study with or without testosterone replacement therapy before being followed for the following year at the clinic while receiving standard of care consisting of diet and exercise counseling (for healthy lifestyle change) and testosterone replacement therapy. This study will determine if long-term lifestyle change and testosterone replacement therapy with associated improvement in physical and metabolic health can be maintained in obese older adults.