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Overweight clinical trials

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NCT ID: NCT06331481 Active, not recruiting - Overweight Clinical Trials

The Effect of Over Weight on Oocytes Quality in IVF Patients

IVF
Start date: February 1, 2022
Phase:
Study type: Observational

Obesity is an increasing worldwide problem and a risk factor for many diseases. The effect of obesity on female fertility has been extensively tested. Obese women have increased time to pregnancy and remain subfertile even in the absence of ovulatory dysfunction. They present with higher incidence of infertility compared to normal weight women. This study is prospective observational cohort study performed between February 2022 until June 2022 in a single university-affiliated hospital.

NCT ID: NCT06270810 Active, not recruiting - Overweight Clinical Trials

Cardiometabolic Effects of Combined Aerobic Exercise and Non-Exercise Physical Activity

Start date: March 11, 2024
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to investigate whether increasing non-exercise physical activity combined with aerobic exercise in overweight young women is superior to performing aerobic exercise alone in terms of some cardiometabolic variables. The main question it aims to answer is: • Do both increasing non-exercise physical activity and doing aerobic exercise add more beneficial cardiometabolic effects to performing aerobic exercise alone in overweight young women? To answer this question, overweight young women will be randomly assigned to two different groups of this research. Volunteers in one of the groups will do moderate-intensity aerobic training and the other group will increase their non-exercise physical activities in addition to moderate-intensity aerobic training. Then researchers will compare two groups to see the differences in cardiometabolic variables.

NCT ID: NCT06256562 Active, not recruiting - Obesity Clinical Trials

A Study of GZR18 Injection in Obese/Overweight Patients

Start date: June 8, 2023
Phase: Phase 2
Study type: Interventional

This study is a multicenter, randomized, placebo-controlled phase II clinical study to evaluate the efficacy, safety, tolerability, and pharmacokinetics of GZR18 injection in Chinese adult obese/overweight subjects.

NCT ID: NCT06248307 Active, not recruiting - Clinical trials for Overweight and Obesity

Evaluation of Protein Bars on Weight Management and Osteoarthicular Health

COLARTIC
Start date: November 15, 2023
Phase: N/A
Study type: Interventional

The goal of this intervention study is to evaluate the efficacy in subjects with overweight or obesity of protein bars consumption. The main questions it aims to answer are: - Does the regular consumption of these protein bars help to loose weight? - Does the regular consumption of these protein bars help to improve the osteoarticular health? Participants will be asked to follow the indications of consumption of the bars togather with healthy nutritional advice during 16 weeks. Researchers will compare exparimental Versus placebo groups to see if weight is lost in similar or different ways.

NCT ID: NCT06247748 Active, not recruiting - Clinical trials for Diabetes Mellitus, Type 2

Influence of JY09 on Pharmacokinetics of Metformin , Rosuvastatin , and Digoxin and the QT Interval Study in Overweight Chinese Subjects

Start date: October 19, 2023
Phase: Phase 1
Study type: Interventional

This trial is conducted in china. The aim of the trial is as follows: - To assess the effect of multiple subcutaneous injections of JY09 injection on the pharmacokinetic (PK) profile of multiple oral doses of metformin hydrochloride tablets, a single oral dose of Rosuvastatin calcium tablets, or digoxin tablets in overweight Chinese subjects; - To assess the effect of multiple subcutaneous injections of JY09 injection on QT interval in overweight Chinese subjects.

NCT ID: NCT06214221 Active, not recruiting - Metabolic Syndrome Clinical Trials

Using Signos mHealth Platform in Adults for Weight Management

SWEET
Start date: January 2, 2024
Phase: N/A
Study type: Interventional

Metabolic syndrome and resulting downstream health effects remains a growing health concern. In published trials, the use of continuous glucose monitoring (CGM) assists behavioral changes efforts, leading to improved adherence and results from diet and exercise changes in individuals with obesity. Mobile health (mHealth) platforms provide satisfactory, easy-to-use tools that help participants in the pursuit of weight change goals. The investigators hypothesize that the use of CGM data and targeted coaching and nutrition education will assist with weight optimization goals in the general (non-diabetic) population using the Signos mHealth platform, with associated health benefits.

NCT ID: NCT06139055 Active, not recruiting - Healthy Volunteers Clinical Trials

A Study of Multiple-ascending Doses of GSBR-1290 in Healthy Overweight/Obese Participants

Start date: October 2, 2023
Phase: Phase 1
Study type: Interventional

The purpose of this study is to compare the safety, tolerability, pharmacokinetic (PK), and comparative bioavailability of repeated administration of GSBR-1290 in healthy overweight/obese participants.

NCT ID: NCT06089876 Active, not recruiting - Physical Inactivity Clinical Trials

The Use of Mobile Applications in Obese and Overweight Adolescents for Health Improvement

Start date: September 25, 2023
Phase: N/A
Study type: Interventional

Overweight and obesity, understood as an accumulation of abnormal and excessive fat, are the second leading cause of preventable and avoidable mortality in developed countries, with more than 340 million children and adolescents affected by this disease worldwide. As a consequence, overweight and obesity at an early age is already considered a pandemic by the World Health Organization (WHO), with a high incidence in developed countries. The abuse of new technologies has remained at worrying levels in the post-COVID period, favoring an increase in the adolescent population considered sedentary. In this regard, up to 70% of adolescents show sedentary behaviors, especially affecting the time spent on screens by both males (93.8%) and females (87.2%). Thus, the use of the cell phone has been shown to be a determining factor, since between 10% and 16% of adolescents show a problematic use of this device, affecting, among other aspects, their behavior during their free time. In recent years there has been an increase in sedentary time among adolescents and a decrease in the practice of physical activity that has favored a greater accumulation of body fat and increased the probability of being overweight or obese. In this context, some studies have tried to encourage the practice of physical activity in the school context in overweight and obese population, being these interventions effective to improve body composition. However, these interventions also have their detractors, who argue that the hours of Physical Education are too limited to dedicate so much time to a single content, and that the pedagogical component is often overlooked in their implementation. As an alternative to the above, it has been suggested that Physical Education classes could be used to promote interventions that encourage adolescents to practice physical activity in their free time, and mobile applications could be used to monitor the activity carried out by adolescents, but also as an element that generates adherence and enjoyment in this population. Research in this population using these technologies is scarce, therefore, this project aims to determine the effectiveness of a ten-week intervention promoted from the subject of physical education in which a mobile application is used after school hours on physical activity, body composition and fitness in overweight or obese adolescents.

NCT ID: NCT06074926 Active, not recruiting - Pediatric Obesity Clinical Trials

Promoting Food Acceptance Through Positive Parenting: the Play and Grow Study

Start date: October 30, 2023
Phase: N/A
Study type: Interventional

Approximately one half of adults and one-fifth of children have obesity, including 14% of 2-5-year-olds. Early obesity prevention is essential as children who are overweight by age 5 are at increased risk for later obesity. Dietary intake is inextricably linked to weight status, and the majority of young children fail to meet intake recommendations, with socioeconomically disadvantaged and racial/ethnic minority children at increased risk of poor diet quality. However, children's liking of healthier foods predicts their intake, and children can learn to like healthier foods via experience. The current study brings together evidence from the parenting and learning literatures to: 1) examine effects of a novel learning strategy leveraging positive parent-child interactions on 3-5-year-old children's vegetable acceptance and dietary intake, as well as to explore 2) individual differences in learning strategy effects.

NCT ID: NCT06067126 Active, not recruiting - Overweight Clinical Trials

Post-delivery Maternal-offspring Obesity and Metabolic Risk After a Prepregnancy Weight-loss Intervention

PrepareD
Start date: April 3, 2019
Phase:
Study type: Observational

The goal of PrepareD is to examine whether the prepregnancy weight-loss intervention administered during the Prepare trial [NCT02346162] has an influence in the postnatal period. PrepareD is a cohort study (no intervention) that will address new specific aims through one in-person visit with mothers and children, dietary recalls, actigraphy, and the use of medical record weights. The goal is to collect data when the child is 3 years old. However, due to the COVID-19 pandemic, the investigators expanded the data collection window in order to collect data up to when the child is 5 years old. The investigators hypothesize that intervening on women before pregnancy is the key to breaking the multigenerational cycle of obesity.