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Osteoarthritis, Hip clinical trials

View clinical trials related to Osteoarthritis, Hip.

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NCT ID: NCT06323018 Not yet recruiting - Clinical trials for Cardiovascular Diseases

Effects of Remote Ischaemic Preconditioning in Cemented Hip Arthroplasty.

PRINCIPAL
Start date: March 2024
Phase: N/A
Study type: Interventional

Total joint arthroplasty is one of the best treatment options for end-stage osteoarthritis. Cemented hip arthroplasty is mainly indicated for elderly patients with poor bone quality and multiple comorbidities. Bone cement implantation syndrome is associated with cemented hip arthroplasty and it has been shown to increase cardiovascular and renal complication and brain damage postoperatively. The aim of this project is to elucidate whether remote-ischemic preconditioning (RIPC) has multi-organ protective effect in cemented hip arthroplasty patients.

NCT ID: NCT06282666 Not yet recruiting - Quality of Life Clinical Trials

Lumbar ESPB in Hip Replacement Surgery

ESPB_HIP
Start date: February 19, 2024
Phase: N/A
Study type: Interventional

In this study, continuous erector spinae plane block (ESPB) will be compared to continuous epidural analgesia in patients undergoing elective hip replacement surgery. Opioid consumption, pain severity, quadriceps femoris muscle strength, ability to walk, and quality of recovery will be evaluated. Moreover, chronic pain severity in months after the hospital discharge will be assessed.

NCT ID: NCT06272422 Not yet recruiting - Coxarthrosis Clinical Trials

Comparison of the Restoration of Hip Biomechanical Parameters by CT Measurement Between the 3 Surgical Techniques: RSA/Minihip/THA - Hip Replacement: 3D Planning

HIP3D
Start date: March 2024
Phase:
Study type: Observational

The study will analyze hip biomechanical parameters using EOS radiographic measurements pre- and post-operatively (3 months) and post-operatively (3 months) CT scans after total hip replacement (THR), neck-preserving THR of the Minihip type or hip resurfacing (HR). Clinical results will be assessed at 3 months and 1 year after surgery. To this end, two types of examination are carried out, both of which are used in current practice: - Pre-operatively: EOS radiography - Post-operatively: EOS radiograph and CT scan Inclusion (m-3; m-1) : - Patient information at pre-operative visit - Non-opposition of patient, family member or legal guardian, if applicable - Questionnaires and clinical examination (standard management) - EOS during anesthetic consultation Follow-up visit (m+3): - Post-operative follow-up consultation EOS and CT scan (1 week prior to visit) + questionnaire and clinical examination Follow-up visit (m+12): - Post-operative check-up, questionnaire and clinical examination

NCT ID: NCT06263569 Completed - Hip Osteoarthritis Clinical Trials

Effectiveness of Total Hip Arthroplasty for Patients With Osteoarthritis, a Target Trial Emulation Study

EAGLE
Start date: May 24, 2023
Phase:
Study type: Observational [Patient Registry]

The aim of this study is to assess the effect of total hip arthroplasty on hip disability and pain compared to non-surgery in patients with hip osteoarthritis, using target trial emulation to emulate a randomized controlled trial.

NCT ID: NCT06258369 Not yet recruiting - Clinical trials for Primary; Coxarthrosis

Gait Initiation and Transition From Double to Single Support in Patients With Unilateral Primary Coxarthrosis

COXAM
Start date: February 2024
Phase: N/A
Study type: Interventional

The study consists to evaluate the impact of prosthetic surgery (PTH and RTH) on kinematic and dynamic parameters (joint torques) of the lower limbs during gait initiation in patients with primary coxarthrosis. Patients included in the study will undergo a three-dimensional gait analysis. Dynamic gait analysis is multidimensional, measuring kinematic parameters (joint amplitudes: ankles, knees, hips, etc.) and dynamic parameters (assessment of joint torque from ankle, knee, hip to lower limb during gait initiation).

NCT ID: NCT06257160 Not yet recruiting - Hip Arthropathy Clinical Trials

Superiority Randomized Controlled Trial of Ultrasound-guided PENG Block Compared to Surgical Infiltration in the Analgesia of Posterior Total Hip Arthroplasty Surgery

PENGORINF
Start date: March 2024
Phase: N/A
Study type: Interventional

Pain after total hip replacement (THR) surgery is severe. The target population is elderly and comorbid. Level III analgesics are responsible for significant side effects in this population. Locoregional analgesia, by reducing the consumption of painkillers, is an effective way of reducing morphine or morphine agonist consumption in this surgery. Furthermore, these techniques fit in perfectly with the objectives of accelerated rehabilitation after surgery. Surgical infiltration is a frequently used and effective analgesic technique. PENG block is a new locoregional anesthesia technique which initial results show promising analgesic efficacy and the absence of loss of strength through motor block. In February 2022, we carried out a survey of national anesthetic practices in posterior hip arthroplasty, with the help of the SFAR (Société Française d'Anesthésie-Réanimation). It shows that, despite the lack of plentiful literature on the subject, the PENG block is currently the most frequently performed pre-operative block in hip arthroplasty (PENG block in 39.5% of cases, femoral block in 13% of cases). The survey also shows that in 41.5% of cases, no block is performed, and only intraoperative surgical infiltration is carried out. PENG block and surgical infiltration are therefore the two analgesic techniques most frequently used in France today. It is for these reasons that we feel it is essential to carry out a study comparing these two techniques.

NCT ID: NCT06249958 Recruiting - Clinical trials for Osteoarthritis, Knee

Transforming Rehabilitation: Personalised Care for a Better Quality of Life

PREPARE
Start date: January 8, 2024
Phase:
Study type: Observational

General aim of the project: building and validating an Artificial Intelligence (AI)-based prediction model on rehabilitation outcomes (total joint replacement - TJR - of the hip and knee for primary and secondary osteoarthritis) Purpose of this specific approval request: identifying data from patients admitted for total joint replacement surgery (hip and knee) at Istituto di Ricerca e Cura a Carattere Scientifico (IRCCS) Istituto Ortopedico Galeazzi (IOG) in 2019 and subsequently discharged to inpatient rehabilitation in the same institution.

NCT ID: NCT06233604 Not yet recruiting - Hip Osteoarthritis Clinical Trials

Dexamethasone vs. Dexmedetomidine for ESPB in Pain Management After Hip Arthroplasty

Start date: March 30, 2024
Phase: Phase 4
Study type: Interventional

Effect of perineurial dexamethasone and dexmedetomidine on erector spinal plane block duration for hip arthroplasty

NCT ID: NCT06221709 Recruiting - Hip Osteoarthritis Clinical Trials

Continuous Radiofrequency in Hip Osteoarthritis Pain: A Randomized Clinical Trial.

Start date: February 1, 2024
Phase: N/A
Study type: Interventional

This will be a prospective, single-center, double-blinded, randomized study designed to compare the efficacy of the intraarticular injection of a corticosteroid and the Conventional Radiofrequency (CRF) of the anterior sensory branches to the hip in controlling pain and improving function related to hip osteoarthritis.

NCT ID: NCT06211465 Completed - Clinical trials for Cardiovascular Diseases

Cardiovascular And Metabolic Risk After Arthroplasty

CAMERA
Start date: March 1, 2014
Phase:
Study type: Observational

Osteoarthritis is a chronic joint disease that lacks curative therapy. Epidemiological studies show increase in the burden of disease. Total joint arthroplasty is one of the best treatment options for end-stage osteoarthritis. However, the specific effects of total joint arthroplasty on cardiovascular risk and metabolic profile are largely unknown. The aim of this project is to elucidate how hip and knee total joint arthroplasty impacts cardiovascular risk and metabolomic profile in comparison with general population. We hypothesize that arthroplasty decreases pain, systemic inflammation levels and increases functional status that all lead to decreased metabolic and cardiovascular risk.