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Osteoarthritis, Hip clinical trials

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NCT ID: NCT06358521 Recruiting - Knee Osteoarthritis Clinical Trials

Determining the Impact of a Physiotherapist-led Primary Care Model for Hip and Knee Pain - A Cluster Trial

Start date: October 2, 2023
Phase: N/A
Study type: Interventional

This is a cluster randomized controlled trial to to evaluate the individual and health system impacts of implementing a new physiotherapist-led primary care model for hip and knee pain in Canada.

NCT ID: NCT06342843 Recruiting - Osteoarthritis, Hip Clinical Trials

Direct Superior Approach Versus PosteroLateral Approach in Total Hip Arthroplasty (SPLAsH)

SPLAsH
Start date: February 13, 2024
Phase: N/A
Study type: Interventional

This study will compare postoperative pain, health related quality of life (HRQoL), function, rehabilitation, urinary incontinence, muscle atrophy and component positioning in total hip arthroplasty (THA) using the posterolateral approach (PLA) or the direct superior approach (DSA). In addition, the CT images will be used to validate a new metal artefact reduction technique.

NCT ID: NCT06323018 Recruiting - Clinical trials for Cardiovascular Diseases

Effects of Remote Ischaemic Preconditioning in Cemented Hip Arthroplasty.

PRINCIPAL
Start date: March 20, 2024
Phase: N/A
Study type: Interventional

Total joint arthroplasty is one of the best treatment options for end-stage osteoarthritis. Cemented hip arthroplasty is mainly indicated for elderly patients with poor bone quality and multiple comorbidities. Bone cement implantation syndrome is associated with cemented hip arthroplasty and it has been shown to increase cardiovascular and renal complication and brain damage postoperatively. The aim of this project is to elucidate whether remote-ischemic preconditioning (RIPC) has multi-organ protective effect in cemented hip arthroplasty patients.

NCT ID: NCT06249958 Recruiting - Clinical trials for Osteoarthritis, Knee

Transforming Rehabilitation: Personalised Care for a Better Quality of Life

PREPARE
Start date: January 8, 2024
Phase:
Study type: Observational

General aim of the project: building and validating an Artificial Intelligence (AI)-based prediction model on rehabilitation outcomes (total joint replacement - TJR - of the hip and knee for primary and secondary osteoarthritis) Purpose of this specific approval request: identifying data from patients admitted for total joint replacement surgery (hip and knee) at Istituto di Ricerca e Cura a Carattere Scientifico (IRCCS) Istituto Ortopedico Galeazzi (IOG) in 2019 and subsequently discharged to inpatient rehabilitation in the same institution.

NCT ID: NCT06221709 Recruiting - Hip Osteoarthritis Clinical Trials

Continuous Radiofrequency in Hip Osteoarthritis Pain: A Randomized Clinical Trial.

Start date: February 1, 2024
Phase: N/A
Study type: Interventional

This will be a prospective, single-center, double-blinded, randomized study designed to compare the efficacy of the intraarticular injection of a corticosteroid and the Conventional Radiofrequency (CRF) of the anterior sensory branches to the hip in controlling pain and improving function related to hip osteoarthritis.

NCT ID: NCT06185036 Recruiting - Osteoarthritis, Hip Clinical Trials

Histological Validation of dGEMRIC Indices as a Quantitative Biomarker for Cartilage Damage in the Hip Joint

Start date: September 1, 2022
Phase:
Study type: Observational

In this study, the investigators seek to validate 3D model-based dGEMRIC (delayed gadolinium enhanced MRI of cartilage) values against histologic grading of cartilage quality, using osteochondral samples of the femoral head collected during hip replacement surgery.

NCT ID: NCT06088160 Recruiting - Osteoarthritis, Hip Clinical Trials

Changes in Postural Stability Following THA for OA

CPS
Start date: December 27, 2023
Phase:
Study type: Observational

Total hip arthroplasty (THA) is a common surgery that eases pain, restores functional movement, and improves the overall quality of life in people with severe hip osteoarthritis (OA). Unfortunately, problems with postural stability, commonly known as balance, are still noticed in people even years after the surgery. These postural stability problems typically result in falls. The aim of the proposed study is to investigate how THA surgery affects a person's overall quality of life, both physically and psychologically, in terms of postural stability and balance confidence (self-efficacy) within the first three months after THA for osteoarthritis. This prospective cohort study will focus on people over 60 years old.

NCT ID: NCT06087588 Recruiting - Osteoarthritis Clinical Trials

Pericapsular Nerve Group Block Chemical Neurolysis in Advanced Hip Osteoarthritis

PENG
Start date: October 17, 2023
Phase: Phase 4
Study type: Interventional

PENG neurolysis in advanced osteoarthritis of the hip joint.

NCT ID: NCT06083428 Recruiting - Hip Osteoarthritis Clinical Trials

Erector Spinae vs. Iliopsoas Plane Block for Total Hip Arthroplasty

Start date: October 17, 2023
Phase: Phase 4
Study type: Interventional

Effect of iliopsoas plane block and ESPB on pain management, and NLR and PLR following knee arthroplasty

NCT ID: NCT06075004 Recruiting - Postoperative Pain Clinical Trials

Total Periarticular Infiltration Vs Posterior Periarticular Infiltration Plus PENG Block for Hip Analgesia

Start date: October 18, 2023
Phase: N/A
Study type: Interventional

In a recent study, direct periarticular local anesthetic infiltration (PAI) showed a greater incidence of early quadriceps weakness (33% at 3 hours and 13% at 6 hours) than pericapsular nerve group block (PENGB) in total hip arthroplasty (THA) but, in turn, demonstrated a statistically significant better pain control. Additionally, PENGB could not completely circumvent motor compromise either, particularly at 3 hours (20% incidence), probably secondary to an injectate migration towards the femoral nerve. Posteriorly to this publication, a cadaveric trial looking into the maximum effective volume that spared the femoral nerve resulted in 13.2 mL. This newer evidence led to the design of a strategy that combines both interventions, aiming to obtain the best of them and have a solid alternative for those cases where very early mobilization is pursued. Thus, it is hypothesized that posterior PAI added to a low-volume PENGB (10mL) represents a superior alternative to PAI in terms of strength preservation and provides effective analgesia during the first 24 postoperative hours after THA.