Effect of Consuming Beans for One Month on Blood Lipids, Satiety, Intake Regulation and Body Weight

Obesity Clinical Trial

Official title:

Beans and Potatoes in the Regulation of Food Intake and Risk Factors for Chronic Diseases. Effect of Consuming Beans for One Month on Blood Lipids, Satiety, Intake Regulation and Body Weight

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT00741923
• Other study ID #: OMAF-HEINZbeans
• Secondary ID: BOW-2008
• Status: Completed
• Phase: N/A
• First received: August 25, 2008
• Last updated: June 14, 2012
• Start date: November 2007
• Est. completion date: December 2009

Study information

• Verified date: June 2012
• Source: University of Toronto
• Contact: n/a
• Is FDA regulated: No
• Health authority: Canada: Ethics Review Committee
• Study type: Interventional

Clinical Trial Summary

This project investigates the effect of regular consumption of commercially available processed white beans (5 cups per week) on food intake, body weight, blood pressure, satiety hormones and glycemic response over a 4-week period. We have chosen to provide participants with canned white beans, the most accessible and frequently consumed bean in North America. They are inexpensive, a good source of high quality nutrients and ready to eat. Based upon published literature and short-term studies conducted in our laboratory, we hypothesize that regular consumption of commercially available canned beans will increase satiety and improve the control of food intake, body weight, blood glucose and blood lipids.

Description:

The metabolic syndrome is a clustering of chronic disease risk factors, including abdominal obesity, dyslipidemia, elevated blood pressure and elevated fasting blood glucose.

A main treatment for metabolic syndrome is lifestyle modification (alterations in diet and/or physical activity patterns) resulting in weight loss.

Beans are easily incorporated into the diet and may lead to the attainment and maintenance of healthy a body weight and improved metabolic control.

Canned baked navy beans (with tomato sauce) have a low glycemic response following consumption, however, whether this effect has long-term benefits on glycemic control requires further investigation.

OBJECTIVE

To determine the effect of consuming 5 cups per week of commercially available canned navy beans over 4 weeks on risk factors associated with the metabolic syndrome.

Subjects

Inclusion criteria: Men and women (n=16) between 35 and 55 years of age with a body mass index (BMI) of 27 to 40 kg/m2.

Exclusion criteria: smoking or any major surgery/medical condition within the last 6 months, use of medications that could interfere with the study outcomes, gastrointestinal, liver or kidney disease and women who were pregnant/lactating

Recruitment information / eligibility

• Status: Completed
• Enrollment: 14
• Est. completion date: December 2009
• Est. primary completion date: September 2008
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 35 Years to 55 Years

Eligibility

Inclusion Criteria:

• BMI 27-40 kg/m2

Exclusion Criteria:

• smokers and individuals who have prescribed medications over the past 6 months that could interfere with the study outcomes (i.e. statins, metformin). Breakfast skippers, those on a restricted energy diet or pregnant/lactating women

Study Design

Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Prevention

Related Conditions & MeSH terms

• Body Weight
• Diabetes
• Hypertension
• Metabolic Syndrome
• Metabolic Syndrome X
• Obesity
• Overweight

Intervention

Other:
• navy beans added to regular diet
5 cups per week of commercially available white beans for 4-weeks

Locations

Country	Name	City	State
Canada	Department of Nutritional Sciences, University of Toronto	Toronto	Ontario

Sponsors (2)

Lead Sponsor	Collaborator
University of Toronto	Ontario Ministry of Agriculture, Food and Rural Affairs

Country where clinical trial is conducted

Canada, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	body weight, waist circumference, blood glucose, satiety hormones, and blood lipids, inflammation factor, and glycated haemoglobin		at the beginning and at the end of study	Yes