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Body Weight clinical trials

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NCT ID: NCT06350253 Recruiting - Body Weight Clinical Trials

Comparison Of Measured To Predicted Resting Metabolism

Start date: March 14, 2023
Phase:
Study type: Observational

The purpose of this study is to compare RMR values from the BIA, predicted equations, and indirect calorimetry.

NCT ID: NCT06339840 Not yet recruiting - Obesity Clinical Trials

The Impact of Lifestyle Intervention on Weight and Fertility in Obese Males

Start date: April 1, 2024
Phase: N/A
Study type: Interventional

Obesity, defined by WHO standards as having a body mass index (BMI) equal to or greater than 30 kg/m², affects approximately 800 million people worldwide. It is evident that obesity has become a serious public health issue, resulting in significant health burdens. Previous systematic reviews have indicated an association between obesity and male factor infertility. In populations undergoing assisted reproductive technology (ART), some studies have shown a correlation between increased male BMI and adverse ART outcomes. Furthermore, the negative effects of obesity may also be transmitted to offspring through genetic and epigenetic changes in reproductive cell DNA, increasing their risk of obesity, metabolic diseases, or other chronic conditions. Currently, there is a lack of data on the impact of weight loss in obese men on fertility, and it is unclear which nutritional pattern in lifestyle interventions can more effectively control weight, improve semen quality, and address related endocrine issues in obese men, thereby improving reproductive treatment outcomes. Based on previous literature, we hypothesize that lifestyle interventions, particularly strict low-carbohydrate diets combined with lifestyle guidance, may offer greater health benefits for obese men. These benefits include effective weight loss, improvement in semen parameters, reproductive metabolic health, quality of life related to reproductive health, and the impact on reproductive treatment outcomes. This provides a basis for non-pharmacological intervention strategies and methods for the health of obese men.

NCT ID: NCT06333574 Not yet recruiting - Hypertension Clinical Trials

Weight Management of Dialysis Patients

Start date: April 1, 2024
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to Improve the quality of life in Hemodialysis patient. The main questions it aims to answer are: - [Improve the self-compliance of dialysis patients with weight management] - [alleviate the volume load of dialysis patients and reduce cardiovascular complications] Participants will be divided into two groups based on a weight management regimen: Control group: received routine outpatient management. Specific methods: The dialysis doctor registered the information of the patient's weight and blood pressure at the end of dialysis, and informed the patient of the purpose, role and importance of weight management. Intervention group: On the basis of routine outpatient management, patients or their family members were subjected to remote follow-up management based on wechat, and the follow-up time was 6 months. Specific methods: Same as the control group, the information of weight and blood pressure of the patients was registered at the end of dialysis, and the purpose, role and importance of weight management were informed to the patients. On this basis, a special wechat signal is set up to add patients or patients' family members as wechat friends and establish a wechat interaction platform with patients. In the interdialysis period, remind patients to weigh themselves through wechat (the time of each weighing is fixed, preferably consistent with the time of weighing in the hemodialysis center), control the weight gain during the interdialysis period not to exceed 4.5% of dry weight, and inform patients again about the purpose, role and importance of weight management.

NCT ID: NCT06329388 Completed - Child Development Clinical Trials

Evaluating the Effects of an Oral Protein Supplement on Children's Growth Patterns

Start date: January 18, 2023
Phase: Phase 1/Phase 2
Study type: Interventional

This single-center, randomized controlled pilot study aims to evaluate the efficacy of TruHeight Growth Protein Shake on improving growth patterns in children aged 4-17 years. Over six months, participants will consume the protein shake daily, five times a week, with outcomes measured in terms of type X collagen concentration in urine, height via a stadiometer, and body composition using an INBODY device.

NCT ID: NCT06329271 Recruiting - Clinical trials for Bony Weight Bearing Disorder

After Hip Fracture Nailing, Compare Early Weight Bearing as Tolerated (WBAT) Group With Weight Bearing Restriction(WBR)

Start date: March 8, 2024
Phase: N/A
Study type: Interventional

Purpose: Proximal femur fracture is a major traumatic injury in elderly populations; however, practical postoperative weight-bearing protocols are lacking. Therefore, the purpose of the present study was to investigate whether early weight-bearing status after proximal femur nail fixation is associated with any loss of reduction and evaluate the clinical outcomes of this intervention. Patients and methods: For this prospective single-center clinical trial study, we recruited 60 geriatric proximal femur fracture cases, classified by AO/OTA 2018, receiving intramedullary nail fixation. The participants were assigned to the Early-weight-bearing group (n= 30) or the Weight-bearing restriction group (n = 30). Clinical outcomes included the Harris functional hip score and VAS pain score. Additionally, demographic data, radiological parameters, time to weight-bearing, mortality rate, medical and surgical complications, and final ambulation status were recorded.

NCT ID: NCT06327919 Completed - Clinical trials for Weight Regain After Bariatric Surgery and Food Addiction

Effects of Probiotic Supplementation With Weight Reducing Plan in Patients With Food Addiction and Weight Regain After Bariatric Surgery

Start date: June 1, 2022
Phase: N/A
Study type: Interventional

To study the effects of probiotic supplementation with a weight loss program and cognitive behavioral therapy (CBT) on anthropometric measures, eating behavior, food addiction, and related hormone levels in patients with food addiction and weight regain after bariatric surgery, 50 patients who referred to obesity clinic with weight regain (regaining ≥10% nadir weight) after bariatric surgery (at least 18 months), and food addiction will be randomly allocated to receive a weight loss program and CBT plus either probiotic, or placebo for 12 weeks. At the first and the end of the intervention, anthropometric measurements, eating behavior, food addiction, leptin, serotonin, and oxytocin will be assessed and compared between groups.

NCT ID: NCT06325735 Recruiting - Birth Weight Clinical Trials

Combined Systemic Inflammatory Indices and Birth Weight

Start date: December 1, 2019
Phase:
Study type: Observational

The study aimed to explore the complex relationship between various systemic inflammatory indices and birth weight

NCT ID: NCT06325449 Not yet recruiting - Obesity Clinical Trials

Correlating Improvement in PCOS Symptoms to the Percentage of Body Weight Lost in Females Also Living With Obesity

FLOWERS-PCOS
Start date: April 1, 2024
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to study the effects of a intensive weight loss program (STREAM) in patients living with PCOS. The main questions the investigators aim to answer are: how much weight will these patients lose over a 24-week program, and what other health markers (ie., insulin sensitivity) will improve and by how much? Participants will complete a 24-week weight loss program (STREAM). During this program they will: - weigh themselves - complete regular bloodwork and - fill out a Quality of Life questionnaire at regular intervals

NCT ID: NCT06309576 Not yet recruiting - Obesity Clinical Trials

Experimental Approach to Test Predictions of Body Weight Regulation Models

DIP
Start date: April 2024
Phase: N/A
Study type: Interventional

The regulation of human body weight and fatness is not fully understood. Although some models of regulation have been proposed (set point, dual-intervention point, others), no studies have been designed to test their predictions. In this pilot and feasibility study, the investigators will implement an experimental approach to test the predictions of models of body weight regulation in humans. Men and women with either underweight or obesity will be exposed to a 2-day fasting followed by a 2-day ad-libitum refeeding. During the entire fasting-refeeding period, energy intake and expenditure will be accurately measured within metabolic chambers. The investigators will therefore determine the compensatory responses to fasting elicited to prevent weight loss. The results will serve to design and power future studies to better understand body weight regulation.

NCT ID: NCT06299644 Not yet recruiting - Obesity Clinical Trials

Endoscopic Sleeve Gastroplasty Technique Comparison for Weight Loss

Start date: May 1, 2025
Phase: N/A
Study type: Interventional

The Investigators propose suture plication placement at the distal gastric body drives a significant portion of weight loss in endoscopic sleeve and sutures only need to be placed in the distal gastric body. Therefore, in this pilot study, the investigators aim to compare "belt" with "belt and suspenders" plication pattern using the Endomina system to determine percent total weight loss.