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Clinical Trial Summary

To evaluate the safety, tolerability, pharmacokinetics and EEG pharmacodynamics of single and multiple ascending doses of apimostinel in normal human volunteers


Clinical Trial Description

Single ascending dose (SAD), multiple ascending dose (MAD), double-blind placebo-controlled study in normal human volunteers. Subjects will receive a single 25 mg IV dose of apimostinel or matching placebo, or 8 consecutive days of 1, 5, 10, or 25 mg IV or matching placebo. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05597241
Study type Interventional
Source Gate Neurosciences, Inc
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Status Completed
Phase Phase 1
Start date October 15, 2022
Completion date April 4, 2023

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