Ischemic Stroke Clinical Trial
— CORAISOfficial title:
Coronary Arteriosclerosis in Patients With Acute Ischemic Stroke Prevalence and Characteristics as Measured by CT Angiography, Echocardiography and Biomarkers
Verified date | June 2015 |
Source | Vejle Hospital |
Contact | n/a |
Is FDA regulated | No |
Health authority | Denmark: The Regional Committee on Biomedical Research Ethics |
Study type | Observational |
The specific objectives of this thesis are in a cohort of patients with an acute ischemic
stroke,
1. To establish the degree of coronary arteriosclerosis.
2. To describe left ventricular systolic and diastolic function in relation to changes of
NT-proBNP.
Status | Completed |
Enrollment | 25 |
Est. completion date | May 2010 |
Est. primary completion date | May 2010 |
Accepts healthy volunteers | No |
Gender | Both |
Age group | 18 Years and older |
Eligibility |
Inclusion Criteria: 1. Age = 18 years old 2. Symptoms suggestive of an acute ischemic stroke 3. Informed consent Exclusion Criteria: 1. Present intracerebral or subarachnoid haemorrhage 2. Present intracerebral vascular malformation 3. Present transient ischemic attack 4. Prior coronary bypass surgery or percutaneous coronary intervention 5. Pacemaker 6. Allergy to contrast 7. Lack of cooperation |
Observational Model: Cohort, Time Perspective: Prospective
Country | Name | City | State |
---|---|---|---|
Denmark | Department of Cardiology, Vejle Hospital | Vejle |
Lead Sponsor | Collaborator |
---|---|
Vejle Hospital |
Denmark,
Barber M, Morton JJ, Macfarlane PW, Barlow N, Roditi G, Stott DJ. Elevated troponin levels are associated with sympathoadrenal activation in acute ischaemic stroke. Cerebrovasc Dis. 2007;23(4):260-6. Epub 2006 Dec 29. — View Citation
Dimant J, Grob D. Electrocardiographic changes and myocardial damage in patients with acute cerebrovascular accidents. Stroke. 1977 Jul-Aug;8(4):448-55. — View Citation
Etgen T, Baum H, Sander K, Sander D. Cardiac troponins and N-terminal pro-brain natriuretic peptide in acute ischemic stroke do not relate to clinical prognosis. Stroke. 2005 Feb;36(2):270-5. Epub 2004 Dec 16. — View Citation
Fure B, Bruun Wyller T, Thommessen B. Electrocardiographic and troponin T changes in acute ischaemic stroke. J Intern Med. 2006 Jun;259(6):592-7. — View Citation
Goldstein DS. The electrocardiogram in stroke: relationship to pathophysiological type and comparison with prior tracings. Stroke. 1979 May-Jun;10(3):253-9. — View Citation
Iltumur K, Yavavli A, Apak I, Ariturk Z, Toprak N. Elevated plasma N-terminal pro-brain natriuretic peptide levels in acute ischemic stroke. Am Heart J. 2006 May;151(5):1115-22. Erratum in: Am Heart J. 2007 Mar;153(3):444. Yavavli A [added]; Karabulut, Aziz [removed]; Aluclu, Ufuk[removed];. Am Heart J. 2007 Feb;153(2):312. — View Citation
Jensen JK, Atar D, Mickley H. Mechanism of troponin elevations in patients with acute ischemic stroke. Am J Cardiol. 2007 Mar 15;99(6):867-70. Epub 2007 Feb 2. Review. — View Citation
Jensen JK, Korsholm L, Høilund-Carlsen PF, Atar D, Kristensen SR, Mickley H. The relation between electrocardiographic ST-T changes and NT-proBNP in patients with acute ischemic stroke. Scand Cardiovasc J. 2007 Oct;41(5):294-8. — View Citation
Jensen JK, Kristensen SR, Bak S, Atar D, Høilund-Carlsen PF, Mickley H. Frequency and significance of troponin T elevation in acute ischemic stroke. Am J Cardiol. 2007 Jan 1;99(1):108-12. Epub 2006 Nov 9. — View Citation
Jensen JK, Mickley H, Bak S, Korsholm L, Kristensen SR. Serial measurements of N-terminal pro-brain natriuretic peptide after acute ischemic stroke. Cerebrovasc Dis. 2006;22(5-6):439-44. Epub 2006 Aug 11. — View Citation
Khechinashvili G, Asplund K. Electrocardiographic changes in patients with acute stroke: a systematic review. Cerebrovasc Dis. 2002;14(2):67-76. Review. — View Citation
Lindgren A, Wohlfart B, Pahlm O, Johansson BB. Electrocardiographic changes in stroke patients without primary heart disease. Clin Physiol. 1994 Mar;14(2):223-31. — View Citation
* Note: There are 12 references in all — Click here to view all references
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