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Coronary Arteriosclerosis clinical trials

View clinical trials related to Coronary Arteriosclerosis.

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NCT ID: NCT03349385 Recruiting - Clinical trials for Coronary Arteriosclerosis

Registry of Secondary Revascularization

REVASEC
Start date: November 22, 2017
Phase: N/A
Study type: Observational [Patient Registry]

The study will evaluate patients with, at least, one previous procedure of coronary revascularization (surgical, percutaneous or both), that are referred for a new, clinically indicated, diagnostic coronary angiography, to describe their clinical characteristics, management, and prognosis, and will propose a prognosis-oriented classification.

NCT ID: NCT03315234 Recruiting - Clinical trials for Coronary Artery Disease

Correlation of Genetic Polymorphisms and Clinical Parameters With the Complexity of Coronary Artery Disease

Start date: September 1, 2016
Phase: N/A
Study type: Observational [Patient Registry]

The purpose of the research project is to investigate the potential association of 6 genetic polymorphisms with the complexity and the severity of coronary artery disease (SYNTAX score). The aim of the study is to combine genetic, clinical and laboratory data in order to create a prognostic tool that will enable an individualized therapeutic patient approach.

NCT ID: NCT03312179 Completed - Clinical trials for Coronary Artery Disease

STEMI and Incretins Treatment

Start date: January 1, 2017
Phase: N/A
Study type: Observational [Patient Registry]

ST elevation myocardial infarction (STEMI) patients affected by multivessels coronary artery stenosis, represent a clinical relevant problem. The management and prognosis of these patents are supported by few literature data. Therefore, in this study authors enrolled real world diabetic vs. non diabetic patients admitted for STEMI and associated to multi vessels coronary disease. Then these diabetics were divided in incretin users (6 months of incretin treatment before study enrollment) vs. never incretin users. In these patients authors studied all cause mortality, cardiac mortality, and major adverse cardiac events at 12 months follow up.

NCT ID: NCT03280433 Recruiting - Clinical trials for Coronary Artery Disease

Influence of EPICardial Adipose Tissue in HEART Diseases: EPICHEART Study

EPICHEART
Start date: September 1, 2014
Phase: N/A
Study type: Observational

This translational study was designed to explore the association of the quantity and quality of epicardial adipose tissue (EAT) with coronary artery disease (CAD), left atrial remodeling and postoperative atrial fibrillation in a high cardiovascular disease-risk population. The investigators expect to identify new biochemical factors and biomarkers in the crosstalk between the epicardial adipocytes, coronary plaques and atrial cardiomyocytes that are involved in the pathogenesis of atherosclerosis and atrial fibrillation, respectively.

NCT ID: NCT02919124 Recruiting - Clinical trials for Coronary Arteriosclerosis

Epicardial Echocardiography of Coronary Anastomoses Using the Echoclip Device

Start date: September 2016
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate whether use of the echoclip device (an ultrasound transducer positioning device which can stabilize the involved part of the myocardium on the beating heart) facilitates imaging of coronary bypass anastomoses during coronary bypass surgery. A total of 100 low risk patients undergoing elective on-pump coronary bypass surgery will be included in the study in order to evaluate if the surgeons can visualize the coronary anastomoses before closure of the sternum. Ultrasonograpic pictures will be analyzed directly peroperatively and electronically post-operatively in order to evaluate if selected areas of the anastomoses can be visualized. Use of the echoclip devise will be considered a success if at least 80% of the anastomoses can be visualized.

NCT ID: NCT02639962 Recruiting - Clinical trials for Coronary Arteriosclerosis

Characteristics of Culprit Lesion and Changes in Plaque Composition. A Dual Energy Cardiac CT Study

S-20130009
Start date: September 2014
Phase: N/A
Study type: Observational

Identifying patients who are at risk for a future myocardial infarction, is still one of the biggest challenges in cardiology. In this study the investigators will investigate culprit lesion in patients with NSTEMI and the ability of cardiac CT with dual energy computed tomography (DECT) scanning to describe and identify plaques that may be vulnerable. The investigators will also describe changes in characteristic in both stable and unstable plaques during 1 year follow up of NSTEMI and a matching group of stable angina pectoris (SAP) patients.

NCT ID: NCT02542007 Active, not recruiting - Clinical trials for Coronary Arteriosclerosis

Safety and Efficacy of the Combo Bio-engineered Sirolimus-eluting Stent Versus the Nano Polymer-free Sirolimus-eluting Stent in the Treatment of Patients With de Novo Stenotic Lesions

RECOVERY
Start date: May 2015
Phase: N/A
Study type: Interventional

To evaluate the safety, efficacy and deliverability of the Combo bio-engineered sirolimus-eluting stent versus the Nano polymer-free sirolimus- eluting stents in the treatment of patients with de novo stenotic lesions of native coronary artery.

NCT ID: NCT02494557 Completed - Clinical trials for Coronary Arteriosclerosis

Risk Stratification for Coronary Artery Disease With Type 2 Diabetic Patients

CAD-risk
Start date: September 2014
Phase: N/A
Study type: Observational

Diabetic type 2 patients (DB2) has a higher prevalence of coronary artery disease (CAD) than non-diabetic persons. Presence of CAD results in murmurs arising from the filling of the arteries and can be detected by the CADScor System and can together with biological patient profile indicate the risk of presence of CAD in the patient. In the pilot study 100 asymptomatic DB2-patients examined with CADScor System and biomarkers will be compared with computed tomography (CT) cardiography and single-photon emission computed tomography (SPECT) for assessing if combination of patient profile (gender, age etc) combined with above measures may give rise to new improved risk scoring method for he DB2-patient.

NCT ID: NCT02490397 Recruiting - Clinical trials for Myocardial Infarction

Impact of Daylight on Patients With Acute Myocardial Infarction

Start date: July 2015
Phase: N/A
Study type: Interventional

The study tests if intense light could be a potential therapy in humans after myocardial infarction by inducing Per2.

NCT ID: NCT02151812 Active, not recruiting - Clinical trials for Coronary Artery Disease

Comparison of Agent™ and SeQuent® Please Paclitaxel Coated Balloon Catheters in Coronary In-stent Restenosis (AGENT-ISR)

AGENT-ISR
Start date: August 2014
Phase: N/A
Study type: Interventional

The primary objective of this study is determine the safety and performance of the Agent™ Paclitaxel-Coated PTCA Balloon Catheter compared to the SeQuent® Please Paclitaxel-Releasing Coronary Balloon Catheter for the treatment of patients with narrowed previously-stented coronary arteries (in-stent restenosis). The performance will be determined at six months post-procedure by quantitative coronary angiography (QCA) to measure Late Lumen Loss (LLL) in the re-opened stented segment. QCA results will be assessed by an independent, blinded angiographic core lab. Study statistical hypothesis: The loss of in-stent luminal diameter at six months after treatment of the restenosed stent with the Agent™ study device is not larger than the respective LLL after treatment with the SeQuent® Please control devices, i.e. study device is non-inferior to the control device with respect to LLL.