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Ischemic Stroke clinical trials

View clinical trials related to Ischemic Stroke.

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NCT ID: NCT06408636 Completed - Atrial Fibrillation Clinical Trials

Prognostic Role of LA Strain in Acute Myocardial Infarction

CMR-MI
Start date: September 2, 2019
Phase:
Study type: Observational

This is a single-center retrospective observational study in which we consecutively selected patients diagnosed with acute myocardial infarction from September 2019 to March 2024 at the Affiliated Hospital of Xuzhou Medical University. Inclusion criteria: 1. CMR was completed during all hospitalizations; 2. complete clinical data; 3. received continuous cardiac monitoring during hospitalization. Exclusion criteria: 1. unclear or non-compliant CMR images; 2. previous history of myocardial infarction; 3. malignant tumors diseases. Dedicated cardiovascular imaging software CVI42 (cvi42® version 5.13.5, Circle Cardiovascular Imaging, Canada) was used for image analysis. LA strain was obtained by cardiac MRI feature tracking. Patient prognosis was obtained through chart notes and telephone follow-up. Major events included atrial fibrillation, ischemic stroke, and all-cause mortality.

NCT ID: NCT06388772 Completed - Clinical trials for Acute Ischemic Stroke

Study to Assess PK, Safety and Tolerability Early in Healthy Subjects

Start date: July 5, 2021
Phase: Phase 1
Study type: Interventional

The purpose of this study is to assess the safety, tolerability and pharmacokinetics (PK) of QHRD106 early in Chinese healthy subjects with single doses.

NCT ID: NCT06380699 Completed - Clinical trials for Acute Ischemic Stroke

Study to Assess PK, Safety and Tolerability in Healthy Subjects

Start date: March 16, 2023
Phase: Phase 1
Study type: Interventional

The purpose of this study is to assess the safety, tolerability, pharmacokinetics (PK) and pharmacodynamics (PD) of QHRD106 in Chinese healthy subjects with single and multiple doses.

NCT ID: NCT06332846 Completed - Stroke, Ischemic Clinical Trials

Oral Health in Patients Hospitalized Because of Ischemic Stroke

Start date: October 10, 2019
Phase:
Study type: Observational

Maintaining good oral health is essential for general health and quality of life. Results of many anal-yses showed that stroke patients had poorer oral condition and worse periodontal status than control population. The aim of the study was to carry out a clinical observation concerning condition of oral health in stroke patients and healthy population. The oral health was assessed in patients with stroke and in (control group). The following elements were assessed: missing teeth, the presence of active caries foci, the presence of existing fillings and prosthetic restorations. To assess oral hygiene API (Approximal Plaque Index) was used. As part of periodontal examina-tion, the following were assessed: the presence of dental deposits, the depth of the existing periodontal pockets, tooth mobility according to Hall and Sulcus Bleeding Index during probing (SBI).

NCT ID: NCT06326801 Completed - Stroke, Ischemic Clinical Trials

Resistive Diaphragmatic Breathing Exercise With Pursed Lips Breathing Exercise in Sub-acute Stroke Patients

Start date: September 1, 2023
Phase: N/A
Study type: Interventional

To determine whether resistive diaphragmatic breathing exercise with pursed lips breathing exercise improve pulmonary function in sub-acute ischemic stroke, To determine whether resistive diaphragmatic breathing exercise with pursed lips breathing exercise improve Trunk Control in sub-acute ischemic stroke, To determine whether resistive diaphragmatic breathing exercise with pursed lips breathing exercise improve Functional Capacity in sub-acute ischemic stroke

NCT ID: NCT06290076 Completed - Clinical trials for Acute Ischemic Stroke

A Predictive Model and Scoring System for Severe Complications After Endovascular Thrombectomy

Start date: January 1, 2020
Phase:
Study type: Observational

To establish a predictive model and scoring system for predicting severe complications after thrombectomy. This scoring system can be used to identify high-risk patients after endovascular thrombectomy, guide the early use of adjunctive interventions, and provide reference for future clinical trials.

NCT ID: NCT06289036 Completed - Clinical trials for The Levels of Cerebral Perfusion and Collateral Circulation in Patients With Subacute Stroke

Prognosis in Subacute Ischemic Stroke Using Multimodal Imaging

Start date: February 1, 2021
Phase:
Study type: Observational

We enrolled patients with subacute IS, associated with moderate-to-severe stenosis of the unilateral cervical internal carotid artery, who underwent 4D ASL. Perfusion levels and collateral circulation were compared between groups with favorable prognosis (modified Rankin scale [mRS] ≤ 2) and poor prognosis (mRS > 2).

NCT ID: NCT06236828 Completed - Stroke Clinical Trials

The MRI-based Evaluation of Safety and Efficacy of EVT and SMT: A Retrospective, Multicenter Study

Start date: January 31, 2023
Phase:
Study type: Observational

Acute Basilar Artery Occlusion (ABAO), a condition with a high risk of mortality or disability (up to 80%). The safety and efficacy of endovascular thrombectomy (EVT) in ABAO remains uncertain due to inconsistent evidence from random controlled trials (RCTs). Recent studies have explored the use of MRI in ABAO, this study aims to assess the efficacy and safety of EVT and standard medical therapy (SMT) in the treatment of ABAO within 24 hours of onset. It also aims to explore the feasibility and prognostic value of MRI-based assessment of ABAO infarction using AI image analysis software.

NCT ID: NCT06221826 Completed - Clinical trials for Ischemic Stroke, Acute

MEXIDOL® in the Rehabilitation Treatment of Patients With Acute Cerebral Failure

Start date: April 17, 2023
Phase: Phase 4
Study type: Interventional

The use of metabolic modulators creates prospects for increasing the efficiency of the rehabilitation treatment of patients with acute cerebral failure

NCT ID: NCT06213870 Completed - Clinical trials for Endovascular Thrombectomy

Screening of Endovascular Thrombectomy With MRI in Acute Ischemic Stroke

Start date: August 1, 2022
Phase:
Study type: Observational

The goal of this observational study is to learn about the role of MRI evaluation based on FVH-DWI mismatch principle in preoperative evaluation of endovascular thrombolectomy. The main questions it aims to answer are: - The consistency between MRI and perfusion examination in determining EVT indications. - The consistency of functional independence rate between patients screening with MRI and perfusion.