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Ischemic Attack, Transient clinical trials

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NCT ID: NCT05132465 Active, not recruiting - Stroke, Ischemic Clinical Trials

Liverpool-Heart and bRain Project Stroke Cohort

L-HARP
Start date: October 12, 2021
Phase:
Study type: Observational [Patient Registry]

What research question is being addressed? Can improve the prediction of adverse outcomes be improved for people following a stroke to optimise their treatment and care? How is it of relevance and importance to patients and public? Following a stroke, people are at a higher risk of developing certain conditions including heart failure, another stroke and atrial fibrillation, a type of irregular heart rhythm. In the proposed study, the investigators will look at factors which may increase a person's risk of such conditions following stroke. From this, the investigators will determine if risk scores for these conditions can be improved for people post-stroke. This could help doctors decide what treatments are best. Who would be eligible? All adults at participating hospitals who have had an ischaemic stroke (where the stroke is caused by loss of blood flow to the brain) or a transient ischaemic attack ('mini-stroke') confirmed by a stroke doctor. All patients will be asked to take part in the study, or their family members may be asked to provide advice on their behalf if the patient is unable to. Where is the study being conducted? At participating hospitals in England and Wales. What will the participants undergo? At the time of stroke, patients have a lot of information collected about their health, the investigators will copy information from patient's medical records about their health after they agree to take part in the study. Patients or their family members will also be asked to complete some additional brief questionnaires about their quality of life, wellbeing and fatigue. Some questionnaires such as for cognitive function are already collected for patients following a stroke, but where this information has not been collected, it will be collected for the study. The investigators will ask the patients if they can be contacted in 12-months to repeat the questionnaires and information collected about their health.

NCT ID: NCT05116280 Completed - Stroke Clinical Trials

MACE and PE in Elective Primary TKA & THA

Start date: January 1, 2018
Phase:
Study type: Observational

This study ought to identify the occurence of the major adverse cardiovascular events (MACE) and the pumonary emoblism (PE) in patients undergoing elective primary THA & TKA

NCT ID: NCT05111951 Completed - Stroke Clinical Trials

Mobile Health to Promote Physical Activity Post Stroke

ENAbLE-Swe
Start date: November 1, 2021
Phase: N/A
Study type: Interventional

Support for physical activity is necessary to sustain health and reduce the risk of stroke recurrence after stroke or transient ischemic attack (TIA). Still, rehabilitation services are not available to many of those who potentially would benefit from such services largely due to barriers related to accessibility. While mobile health is a promising strategy to support physical activity, there is a gap in knowledge regarding the implementation of technology that meet the needs of people post stroke or TIA in order to foster adherence and engagement in physical activity. This project therefore seeks to improve health and reduce the risk of recurrent stroke among people post stroke or TIA by increasing the access to physical activity through telehealth. The present project builds on experiences of telehealth-delivered physical activity in Australia where restricted access to health-care services is a longstanding problem. Collaborating researchers in Australia have developed a telehealth program (i-REBOUND- Let's get moving) which has been designed and tested in collaboration with end users, through a series of feasibility and pilot studies. The i-REBOUND program provides support for physical activity through physical exercises supervised by a physiotherapist and behavior change techniques for physical activity (i.e. individual counseling, information, recommendations, goal-setting, self-monitoring and structured follow-ups) across 6 months. The intervention is delivered to people post stroke or TIA in their own homes via video-meeting. This study, which is conducted in Sweden, aims to evaluate if the i-REBOUND program supported by a new mobile application could be delivered as intended through a pilot randomized controlled trial in order to determine the feasibility and preliminary effects in people post stroke or TIA living in urban and rural regions of Sweden.

NCT ID: NCT05044208 Recruiting - Atrial Fibrillation Clinical Trials

Echocardiographic Predictors of Atrial Fibrillation

EPAF-7
Start date: January 1, 2021
Phase:
Study type: Observational

This prospective study aims to identify the diagnostic accuracy of echocardiographic predictors of atrial fibrillation in patients with ESUS (embolic stroke of undetermined source) or TIA (transient ischemic attack).

NCT ID: NCT04972058 Recruiting - Ischemic Stroke Clinical Trials

Philippine Neurological Association One Database - Stroke

PNA1DB-Stroke
Start date: June 1, 2021
Phase:
Study type: Observational [Patient Registry]

This is a pragmatic, multi-center, prospective, observational, non-interventional study and standing database of patients hospitalized for transient ischemic attack (TIA) or stroke in the 11 accredited adult neurology training institutions in the Philippines. Data will be collected from each patient while admitted in the hospital and until hospital discharge. Data collection for this study will span 3 years from study initiation, after which the utility of an extension or a re-implementation of the study will be assessed.

NCT ID: NCT04952311 Recruiting - Clinical trials for Transient Ischemic Attack

Efficacy Study of Clopidogrel in High-risk Population With Acute Non-disabling Cerebrovascular Events Ⅱ

Start date: June 1, 2019
Phase: Phase 3
Study type: Interventional

The purpose of this study was to test whether ticagrelor combined with aspirin can reduce the recurrence rate of stroke within 3 months compared with clopidogrel combined with aspirin in patients at high risk of non-disablement ischemic cerebrovascular events who carry the CYP2C19 function loss allele within 24 hours of onset.

NCT ID: NCT04945174 Recruiting - Clinical trials for Transient Ischemic Attack

Stroke School -Including Physical Exercise, Patient Education and Individual Follow-up Sessions

Start date: June 1, 2022
Phase: N/A
Study type: Interventional

In a randomized controlled trial the effect of 12 weeks of cross-sectorial physical exercise combined with patient education and individual follow-up session is investigated in patients with minor stroke or non-disabling stroke.

NCT ID: NCT04917237 Recruiting - Stroke Clinical Trials

Non-disabling Ischemic Cerebrovascular Event With Apathy

Start date: July 10, 2021
Phase:
Study type: Observational

The burden of non-disabling ischemic cerebrovascular events (NICE) is significantly increased. However, few previous studies have focused on affective impairment after transient ischemic attack (TIA) and minor stroke. Stroke survivors are often described as apathetic. Even though post-stroke apathy (PSA) affects one in three stroke patients,it has not hitherto received much attention. NICE-A is a prospective study aimed to explore the association between baseline apathy and probable incident stroke in a population-based sample of TIA and minor stroke adults.

NCT ID: NCT04790357 Not yet recruiting - Ischemic Stroke Clinical Trials

Assessment of One-shot Cardiac-cervical-intracranial MRI in the Etiological Work up of Ischemic Stroke and Transient Ischemic Attacks

Concise
Start date: April 1, 2021
Phase: N/A
Study type: Interventional

Stroke is a major public health issue in developed countries. A full etiological work up within a short time is critical to implement the appropriate preventive treatment. The etiological work up is actually based on a clinical examination and on a group of paraclinical examinations. The realization of the standard strategy is time consuming, and increase the cost of the medical care. A non-invasive one-shot examination of the heart, the aorta and the cervical and intracranial arteries (cci-MRI) could overcome these disadvantages.The investigator therefore propose to carry out an overall assessment of the performance of the cci-MR in the etiological work up of ischemic strokes and TIAs compared to the reference strategy

NCT ID: NCT04775836 Recruiting - Stroke Clinical Trials

An EHR-based Platform To Facilitate Outcomes and Research Methods in Cerebrovascular Diseases

PLATFORM-CVD
Start date: January 1, 2018
Phase:
Study type: Observational [Patient Registry]

In this protocol, the investigators present methods and preliminary results from the PLATFORM-CVD Study, an EHR-based multicenter cohort. This study will focus on assessing the distribution of major cerebrovascular diseases, determining the risk factors associated with disease incidence and worse in-hospital outcomes, as well as describing the quality of care. Data from this cohort will be used to develop suitable prediction models for cerebrovascular diseases using real-world data and to understand how outcomes for cerebrovascular diseases would change with quality improvement interventions.