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Clinical Trial Summary

The purpose of this clinical study is to evaluate the safety and efficacy of HS-001 CS transplanted into severe heart failure patients with underlying ischemic heart disease for 26 weeks after transplantation.


Clinical Trial Description

This is a multicenter, open-label, two-group dose-escalation, phase I/II study in 10 severe heart failure patients (five in the low-dose group and five in the high-dose group) with underlying ischemic heart disease. After screening period is completed, subjects undergo HS-001 CS transplantation. After transplantation, subjects take immunosuppressant and have efficacy/safety assessments. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04945018
Study type Interventional
Source Heartseed Inc.
Contact Heartseed Inc.
Phone 0363801068
Email contact@heartseed.jp
Status Recruiting
Phase Phase 1/Phase 2
Start date April 19, 2022
Completion date January 31, 2026

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