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Heart Diseases clinical trials

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NCT ID: NCT00121550 Completed - Clinical trials for Cardiovascular Disease

The CLARICOR Trial: Effect of Clarithromycin on Mortality and Morbidity in Patients With Ischemic Heart Disease

Start date: October 1999
Phase: Phase 3
Study type: Interventional

A growing body of evidence links Chlamydia pneumoniae to the progression of coronary heart disease. The purpose of this study is to determine the positive and negative effect of 14 days treatment with clarithromycin 500 mg daily in patients already suffering from stable coronary heart disease. The participants will be followed for at least two years after the treatment. Abbott Laboratories supplied Clarithromycin and placebo tablets.

NCT ID: NCT00119847 Completed - Clinical trials for Cardiovascular Diseases

Electrophysiological Effects of Late PCI After MI

Start date: September 2002
Phase: N/A
Study type: Interventional

The purpose of this study is to determine if opening blocked arteries with heart balloons and stents prevents heart rhythm problems in individuals 3 to 28 days after a heart attack.

NCT ID: NCT00119834 Completed - Clinical trials for Cardiovascular Diseases

Interagency Registry for Mechanically Assisted Circulatory Support (Intermacs)

Start date: June 2005
Phase:
Study type: Observational

The Intermacs registry is a national quality improvement system designed to advance the understanding and application of mechanical circulatory support in order to improve the duration and quality of life in patients with advanced heart failure.

NCT ID: NCT00119821 Completed - Obesity Clinical Trials

Strategies to Reduce Weight Gain in Hypertensive Smokers

Start date: September 2004
Phase: N/A
Study type: Interventional

To evaluate the effectiveness of lifestyle modification following a smoking cessation program in preventing weight gain among hypertensive smokers placed at medical risk by the post-cessation weight gain.

NCT ID: NCT00119795 Completed - Obesity Clinical Trials

Exercise and Weight Loss for Improving Mobility in Older Adults Who Are Obese

CLIP
Start date: August 2005
Phase: N/A
Study type: Interventional

To test the effects of exercise and weight loss on mobility disability of older overweight/obese men and women who have evidence of cardiovascular disease or the metabolic syndrome.

NCT ID: NCT00119782 Completed - Obesity Clinical Trials

Promoting Activity and Changes in Eating (PACE) to Reduce Obesity

PACE
Start date: September 2004
Phase: N/A
Study type: Interventional

Reducing the prevalence of obesity in the population is one of the Healthy People 2010 goals. Increased vigilance is required in all age groups in preventing and reversing overweight and obesity. On an individual level, behavioral factors that influence body weight include eating choices leading to excess calorie intake and physical activity patterns leading to diminished calorie expenditure. An imbalance between the two over time leads to increased weight. On a population basis, the prevalence of overweight is associated with a myriad of influences, including social, behavioral, cultural, and environmental factors as well as genetic and physiological factors. For a majority of overweight individuals, restoring a balance between energy intake and expenditure is difficult, and therefore there is an increasing emphasis on preventing obesity on a population level. The long-term goal of this research is to prevent further increase in rates of obesity in the population. In the adult population of working age, a majority of the day is spent in the worksite, suggesting that interventions at the worksite level may offer the opportunity for success in this age group. It is anticipated that this project will yield important contributions to the understanding of obesity prevention.

NCT ID: NCT00116857 Completed - Depression Clinical Trials

Omega-3 Fatty Acids to Improve Depression and Reduce Cardiovascular Risk Factors

Start date: February 2005
Phase: Phase 3
Study type: Interventional

This study will determine the effects of omega-3 fatty acid (FA) augmentation of sertraline on depression and cardiac endpoints after myocardial infarction (MI).

NCT ID: NCT00116428 Completed - Atrial Fibrillation Clinical Trials

NAVISTAR® THERMOCOOL® Catheter for the Radiofrequency Ablation of Symptomatic Paroxysmal Atrial Fibrillation

Afib IDE
Start date: October 1, 2004
Phase: Phase 3
Study type: Interventional

This trial compares the safety and effectiveness of catheter ablation for PAF with antiarrhythmic drug therapy. The investigational catheter being studied is the NAVISTAR® THERMOCOOL® irrigated-tip catheter. At the time of this study, the NAVISTAR® THERMOCOOL® catheter was FDA-approved for commercial distribution in the U.S. for treating patients with Type I atrial flutter and drug refractory monomorphic ventricular tachycardia post myocardial infarction. The catheter was approved for use in Europe for endocardial ablation for treating cardiac arrhythmias.

NCT ID: NCT00114998 Completed - Obesity Clinical Trials

CV Disease in Adolescents With Type 2 Diabetes

Start date: June 2005
Phase: N/A
Study type: Observational

To study cardiac and vascular structure and function in a population of adolescents with type 2 diabetes mellitus (T2DM) compared to a similar group with obesity alone and a similar non-obese group.

NCT ID: NCT00114907 Completed - Cardiac Disease Clinical Trials

Effects of Black Tea on Cardiovascular Disease in the Mauritian Population

Start date: June 2005
Phase: N/A
Study type: Interventional

It is proposed to investigate the association between consumption of black tea and various selective fasting blood serum and urine biomarkers in a Mauritian population with ischaemic heart diseases. This study, the first of its kind, will provide clinical data on the potential prophylactic propensities of Mauritian black tea against cardiovascular disease, which remains one of the major health threats to the Mauritian population.