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NCT00262691 Clinical Trial

Investigation of Genetic Risk of Cardiovascular Disease in Prospective Cohort Study

Healthy Clinical Trial

Official title:
Investigation of Genetic Risk of Cardiovascular Disease in Prospective Cohort Study, the Kitanagoya Genome (KING) Study for the Local Residents of Kitanagoya, Japan

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT00262691
Other study ID # NU-05-G-0001
Secondary ID
Status Recruiting
Phase N/A
First received December 6, 2005
Last updated September 20, 2007
Start date May 2005

Study information
Verified date September 2007
Source Nagoya University
Contact Mitsuhiro Yokota, MD, PhD
Phone +81-52-759-2111
Email myokota@dpc.aichi-gakuin.ac.jp
Is FDA regulated No
Health authority Japan: Ministry of Health, Labor and Welfare
Study type Observational

Clinical Trial Summary

Cardiovascular disease is a complex multifactorial and polygenic disorder that is thought to result from an interaction between a person's genetic make up and various environmental factors. Although many studies have revealed that several genetic variants increase the risk of cardiovascular disease, the results of these studies remain controversial. The purpose of this study is to identify polymorphisms that confer susceptibility to cardiovascular disease and to clarify the adequacy of reported susceptibility gene polymorphisms. To complete this purpose, we will prospectively study over 5,000 local residents in whom relationship between these polymorphisms and occurrence of cardiovascular disease over 5 years.

Recruitment information / eligibility
Status Recruiting
Enrollment 7000
Est. completion date
Est. primary completion date
Accepts healthy volunteers No
Gender Both
Age group 50 Years and older
Eligibility Inclusion Criteria:

- Healthy subjects who undergo community-based annual health check in Kitanagoya city

Study Design

Observational Model: Case Control, Time Perspective: Longitudinal

Related Conditions & MeSH terms

Locations
Country Name City State
Japan Department of Genome Science, School of Dentistry, Aichi-Gakuin University Nagoya Aichi

Sponsors (2)
Lead Sponsor Collaborator
Nagoya University Aichi Gakuin University

Country where clinical trial is conducted

Japan, 

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