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Depressive Disorder clinical trials

View clinical trials related to Depressive Disorder.

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NCT ID: NCT04299256 Completed - Fatigue Clinical Trials

Benson Relaxation Technique Combined With Music Therapy for Fatigue, Anxiety, and Depression in Hemodialysis Patients

Start date: May 1, 2019
Phase: N/A
Study type: Interventional

This study carried out in the HD unit of a large-scale training and research hospital, and at a dialysis center associated with this hospital located in Ankara, Turkey. Participants will be randomized to one of two study arms. Arm 1: Intervention group Arm 2: Control group Hypothesis 1. The HD patients in the 8-week intervention of BRT combined with music therapy will report lower fatigue scores than those in the control group. Hypothesis 2. The HD patients in the 8-week intervention of BRT combined with music therapy will perceive lower anxiety and depression than those in the control group.

NCT ID: NCT04296734 Completed - Child Development Clinical Trials

Prenatal Depression Prevention Effects on Parenting and Young Child Self-Regulation and Functioning

EPIC
Start date: November 14, 2019
Phase:
Study type: Observational

Poor parenting practices and compromised child self-regulation when a child is 2 ½ - 4 ½ years old are foundational in promoting their later healthy development and adaptive functioning. This project will test whether targeting depressive symptoms with a prenatal preventive intervention prevents disruptions in well-regulated parenting and child self-regulation known to affect families with depressed mothers. This project may have great benefit to society, as preventive interventions delivered prenatally have the potential to influence long-term trajectories of parenting practices and child development which, in turn, can chart a course for future child health and well-being.

NCT ID: NCT04295941 Completed - Clinical trials for Major Depressive Disorder

Long-term Study With Trazodone Once-a-Day

Start date: June 23, 2020
Phase:
Study type: Observational

The aim of the present observational study is to assess the clinical response, functional impairment and quality of life in outpatients with Major Depressive Disorder who demonstrated an initial positive response to the acute treatment with Trazodone once-a-day monotherapy, for up to 24 weeks.

NCT ID: NCT04294654 Completed - Clinical trials for Major Depressive Disorder

Vortioxetine in Patients With Depression and Early Dementia

MEMORY
Start date: February 28, 2020
Phase: Phase 4
Study type: Interventional

This study evaluates the effectiveness of vortioxetine on depressive symptoms in patients with depression and early dementia

NCT ID: NCT04291547 Completed - Depression Clinical Trials

Computerised Behavioural Activation for Young People With Depression

Start date: June 10, 2020
Phase: N/A
Study type: Interventional

The primary aim of this non-randomised feasibility study is to 1) examine the acceptability of a newly developed computerised Behavioural Activation programme (BALM) in treating young people experiencing low mood/depression and 2) assess the feasibility of undertaking a pilot Randomised Controlled Trial (RCT) of the intervention.

NCT ID: NCT04288895 Completed - Clinical trials for Major Depressive Disorder

Open-label, Flexible-dose Study of Vortioxetine in Patients With Depression in India

Start date: February 20, 2020
Phase: Phase 4
Study type: Interventional

The purpose of this study is to evaluate the safety and tolerability of flexible doses of vortioxetine (5 - 20 mg/day) over a period of 12 weeks in patients with depression in India

NCT ID: NCT04286282 Completed - Depression Clinical Trials

Neuroinflammation and Modulating Factors in Depression and HIV

Start date: February 1, 2021
Phase: Phase 2
Study type: Interventional

Determine if depression, which persists after depression treatment at 26 weeks, is associated with increased innate inflammation in a prospective cohort of HIV-infected Ugandans receiving SSRIs in which group psychotherapy is initiated.

NCT ID: NCT04285515 Completed - Clinical trials for Major Depressive Disorder

Clinical Trial Evaluating Lumateperone Monotherapy in the Treatment of Bipolar Depression or Major Depressive Disorder

Start date: February 27, 2020
Phase: Phase 3
Study type: Interventional

This is a randomized, double-blind, placebo-controlled, multicenter study to evaluate the efficacy and safety of lumateperone monotherapy in the treatment of patients with major depressive episodes associated with Bipolar I or Bipolar II Disorder (Bipolar Depression) or major depressive disorder (MDD) who also meet the Diagnostic and Statistical Manual of Mental Disorder, 5th Edition (DSM-5) criteria for mixed-features. The study consists of a Screening Period, a Double-blind Treatment Period, and a Safety Follow-up Period.

NCT ID: NCT04283591 Completed - Anxiety Disorders Clinical Trials

The Effectiveness of Acupuncture Treatment for Post-Stroke Depression and Anxiety Disorder.

Start date: August 1, 2019
Phase: N/A
Study type: Interventional

Poststroke depression is seen with a frequency of up to 30%. Drug options for depression and accompanying sleep problems are limited; In addition, effective doses cannot be increased depending on the comorbidities of the patients and the side effect profiles and drug interactions of the drugs used. Acupuncture has been used in Chinese traditional medicine for more than 2000 years and there are findings that it has positive effects in post-stroke depression and anxiety disorders. The aim of this study is to examine the effectiveness and reliability of acupuncture treatment in depression and anxiety disorders developing after stroke and to reduce the need for multiple drugs and / or high-dose medication in the treatment of these complications. The hypothesis of the study: Acupuncture is an effective and reliable treatment method for depression and anxiety disorders in stroke patients.

NCT ID: NCT04272476 Completed - Clinical trials for Depressive Disorder, Major

The Activation on Prefrontal Cortex With Acupuncture and Moxibustion for Major Depressive Disorder: A Study of Functional Near Infrared Spectroscopy

ACUfNIRS
Start date: January 2014
Phase: Phase 2
Study type: Interventional

This study evaluates the activation on prefrontal cortex with acupuncture and moxibustion for major depressive disorder.Half of participants will receive the treatment of acupuncture and moxibustion, while the other participants will receive the fluoxetine.