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Cryotherapy Effect clinical trials

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NCT ID: NCT05600088 Recruiting - Clinical trials for Coronary Artery Disease

Intracoronary Cryotherapy Effect on Stabilization of Vulnerable Plaque in Patients With NSTEMI or Unstable Angina

POLARSTAR
Start date: October 18, 2022
Phase: N/A
Study type: Interventional

The POLARSTAR study is an early safety and feasibility study to evaluate the performance and safety of the CryoTherapy System (CTS) for the treatment of coronary plaque lesions that are not obstructing blood flow but are at high-risk of rupture which would cause a major heart attack. The CTS is used to apply local freezing of the lesion using a balloon catheter, controlled by a console that regulates in- and outflow of a cooling agent into the catheter. The treatment is expected to stabilize the lesion, diminishing the risk of rupture. The study will enrol subjects with acute coronary disease who have suitable coronary lesions. Subjects will be followed for 1 year after the CTS treatment. Baseline identification of lesions will be done using Coronary CT-angiography (CCTA), which will be repeated at 3 and 9 months after procedure.

NCT ID: NCT05555602 Recruiting - Cryotherapy Effect Clinical Trials

Observation of the Comfort and Efficacy of CO2 Laser Combined With Cryo 6 for Burn or Linear Scars.

Start date: November 23, 2021
Phase: N/A
Study type: Interventional

To investigate the effect of 10,600 nm CO2 laser combined with Zimmer Cryo 6 forced cold air device on the comfort and efficacy of patients with burn scars or post-operative linear scars, and to provide a safer, more effective and more satisfactory program for clinical treatment of burn scars or post-operative linear scars.

NCT ID: NCT05476445 Completed - Pain, Postoperative Clinical Trials

Effect of Cryotherapy and LLLT on Postoperative Pain After Root Canal Treatment

Start date: May 2, 2022
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate the effect of low-level laser therapy (LLLT) and intracanal cryotherapy applications on postoperative pain in endodontic interventions of primary molar teeth with apical periodontitis. 75 patients were randomly assigned to the control, low-level laser and cryotherapy groups.Root canal treatments were performed in a single session. The pain intensity felt by the patients on the preoperative and postoperative 1st, 3rd, 5th and 7th days were recorded using the Wong Baker visual pain scale. Preoperative and postoperative 7th day percussion sensitivity was recorded using the VAS (visual analog scale) scale. The pain scores of the groups at different times after the procedure were compared. Statistical analysis of the data was performed at the 0.05 significance level.

NCT ID: NCT05441995 Not yet recruiting - Pain Clinical Trials

Cryotherapy Efficacy During Pulp Therapy of the Mandibular First Permanent Molars in Children

Start date: June 2022
Phase: N/A
Study type: Interventional

The aim of the study is to assess the efficacy of cryotherapy application on the success of inferior alveolar nerve block (IANB) in reducing pain during pulp therapy of the mandibular first permanent molars with irreversible pulpitis (IP) in children age from 7 to 16 years. The null hypothesis (H0) supposed no difference in pain intensity during pulp therapy of primary molars with IP anesthetized with IANB with and without cryotherapy application. The secondary aim was to evaluate the children's behavior before and after pulpectomy in the two groups.

NCT ID: NCT05395273 Completed - Cryotherapy Effect Clinical Trials

Cryocompression After Total Knee Arthroplasty

Start date: May 10, 2022
Phase: N/A
Study type: Interventional

The overall aim of this study is to evaluate the effectiveness of a cryocompression device after total knee arthroplasty (TKA) compared to standard therapy.

NCT ID: NCT05355584 Completed - Cryotherapy Effect Clinical Trials

Acute Effects of Cryotherapy Duration in Healthy Individuals

Start date: May 20, 2022
Phase: N/A
Study type: Interventional

The study will investigate the acute effects of cryotherapy duration on shoulder muscle strength, flexibility, endurance and dynamic balance in healthy individuals.

NCT ID: NCT05348447 Recruiting - Pain, Postoperative Clinical Trials

Intercostal Nerve Cryotherapy in Patients Undergoing Minimally Invasive Pulmonary Resection

Start date: April 21, 2022
Phase: N/A
Study type: Interventional

This is a research study designed to test whether a treatment called Intercostal Nerve Cryotherapy is an effective way to help control post-surgical pain for patients undergoing minimally invasive pulmonary resection. There are two treatment groups in this study, a cryotherapy group and control group. Cryotherapy is a method of controlling pain by freezing nerves between the ribs that would transmit pain impulses to the brain.

NCT ID: NCT05255146 Not yet recruiting - Post Operative Pain Clinical Trials

Cryoanalgesia and Post-thoracotomy Pain in Minimally Invasive Cardiothoracic Surgery

Start date: September 2024
Phase: N/A
Study type: Interventional

Minimally invasive cardiothoracic surgery is often associated with chronic pain syndrome, out of keeping with the extent of surgical dissection. This is thought to be because of damage to the intercostal nerves by compression and traction by the surgical equipment. Cryoanalgesia is long-standing technique that freezes nerves locally to temporarily block pain sensation, which is currently used to treat acute post-operative pain in lung dissections and the Nuss procedure. We intend to perform a trial to assess whether using cryoanalgesia on intercostal nerves intraoperatively, reduces post-operative pain following minimally invasive cardiothoracic surgery.

NCT ID: NCT05251688 Completed - Cryotherapy Effect Clinical Trials

Cryoanalgesia for Arterial Puncture Pain

Start date: June 1, 2019
Phase: N/A
Study type: Interventional

Arterial puncture is a painful procedure performed to assess patients' acid-base and respiratory status. Pain is a stressful situation for unconscious patients as they cannot communicate their feeling verbally. To control patients' pain and avoid the adverse effects of painkillers, nonpharmacological pain management strategies have been solicited. therefore, this study aimed to investigate the effect of cryoanalgesia on unconscious patients' pain during arterial puncture.

NCT ID: NCT05095909 Recruiting - Clinical trials for Rotator Cuff Injuries

Utility of Intermittent Cryo-Compression Versus Traditional Icing Following Arthroscopic Rotator Cuff Repair

ICC
Start date: March 2023
Phase: N/A
Study type: Interventional

Effective post - operative pain control following orthopedic surgical procedures without excessive reliance upon opioid pain medication has garnered increased attention in recent years. This study will evaluate the utilization of a non-invasive, novel cryo - compression, post-operative modality to improve pain control versus standard ice wraps in the immediate post-operative phase of arthroscopic rotator cuff surgery via a randomized controlled study design. Furthermore, if this study demonstrates improved pain control, improved quality of life and decreased opioid usage with the intermittent cold compression unit, recommendations may be considered for system-wide utilization.