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NCT ID: NCT04687059 Completed - Clinical trials for Rhinitis, Allergic, Seasonal

An Exploratory Study of PQ Grass 27600 SU

Start date: October 19, 2020
Phase: Phase 2/Phase 3
Study type: Interventional

PQGrass309 is aimed at exploring the expected average treatment effect of PQ Grass 27600 SU cumulative dose on symptom and medication score in a field setting. The study will enrol adult subjects with seasonal allergic rhinitis and/or rhinoconjunctivitis (SAR) induced by grass pollen exposure.

NCT ID: NCT04686838 Completed - Alzheimer Disease Clinical Trials

REmote Assessment and Dynamic Response Intervention II

READyR-II
Start date: July 1, 2021
Phase: N/A
Study type: Interventional

The purpose of the READyR II Study is to test a dynamic tailoring phase of a remote assessment for changing dementia-related care needs.

NCT ID: NCT04686604 Completed - Heart Failure Clinical Trials

PRagmatic Trial Of Messaging to Providers About Treatment of Heart Failure in the Inpatient Setting

PROMPT-HF
Start date: July 7, 2021
Phase: N/A
Study type: Interventional

A randomized single-blind interventional trial to test the effectiveness of an electronic medical record-based best practice alert recommending evidence-based medical therapies versus usual care in inpatient adult patients presenting with heart failure with reduced ejection fraction.

NCT ID: NCT04686552 Completed - Clinical trials for Overweight and Obesity

Effect Cinnamon Spice on Postprandial Glucose and Insulin Responses

CINNI
Start date: January 1, 2018
Phase: N/A
Study type: Interventional

The objective of the proposed study is to investigate the effect of cinnamon on the postprandial glycemic response to a high glycemic index meal in normal and overweight/obese prediabetic subjects

NCT ID: NCT04686383 Completed - Clinical trials for Resistant or Refractory Solid Tumors

Safety, Tolerability, and Pharmacokinetics of CAL056 Mesylate in Patients With Resistant or Refractory Solid Tumors

Start date: December 29, 2020
Phase: Phase 1
Study type: Interventional

This is a multi-center, open-label, dose-escalation, phase I study to evaluate the safety, tolerability, pharmacokinetics (PK), preliminary efficacy, and pharmacodynamics of CAL056 mesylate in cancer patients with resistant or refractory solid tumors.

NCT ID: NCT04686279 Completed - HIV/AIDS Clinical Trials

Tenofovir Rectal Douche to Prevent HIV Transmission Among Adolescents (ATN DREAM)

Start date: April 1, 2021
Phase: Phase 1
Study type: Interventional

ATN DREAM is an early phase-1, open label study to examine the safety, pharmacokinetics (PK), pharmacodynamics (PD), and acceptability of a one-dose tenofovir (TFV) medicated douche. The overall goal is to inform the design of an extended safety study of an on-demand and behaviorally congruent TFV douche to confer protection from HIV acquisition in an outpatient pre-RAI context

NCT ID: NCT04686266 Completed - Clinical trials for Caregiver Stress Syndrome

Improving Self-Care of Behavioral Variant Frontotemporal Dementia Caregivers

ViCCY
Start date: December 16, 2020
Phase: N/A
Study type: Interventional

The research study is being conducted to evaluate the efficacy of a virtual support intervention to reduce stress and poor self-care for caregivers of persons with behavioral variant Frontotemporal Degeneration (bvFTD) compared to receiving health information alone.

NCT ID: NCT04686084 Completed - Dental Diseases Clinical Trials

Dual Energy Cone-Beam Computed Tomography (DE-CBCT) Assessment of Jaw Bone Density

Start date: March 26, 2021
Phase: N/A
Study type: Interventional

Current radiologic imaging modalities used in dentistry provide information on the morphology of the hard tissues. Additional information on the density of bone has practical relevance, for example, in dental implant treatment planning, where local bone quality is a known strong predictor of successful implant osseointegration. The Dual-Energy Cone Beam Computed Tomography (DE-CBCT) device is designed to overcome limitations of traditional imaging and will provide assessment of jaw bone density in additional to morphological information. This clinical trial will examine the application of DE-CBCT to assess jaw bone density and compare Hounsfield units (HU) values with multidetector CT, an established standard for assessing BD.

NCT ID: NCT04685811 Completed - Clinical trials for Metastatic Prostate Adenocarcinoma

Evaluation of PSMA Antagonist Produced by Two Different Methods

Start date: December 9, 2020
Phase: Phase 1/Phase 2
Study type: Interventional

Patients with metastatic prostate cancer will undergo two protocol 68Ga-PET scans within 24-48 hours with 68Ga-PSMA-cyclotron and 68Ga-PSMA-generator radiotracers. The goal of the study is to evaluate repeatability and equivalence across the different 68Ga-PSMA production methods. This research study is being conducted to assess whether the PET/CT imaging results, as generated from the two different 68Ga production methods, are equivalent.

NCT ID: NCT04685733 Completed - Blood Pressure Clinical Trials

Caretaker Hemodynamic Parameters Validation

Start date: February 1, 2018
Phase:
Study type: Observational

Comparison studies comparing hemodynamic parameters provided by the Caretaker against respective Gold Standard references.