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Blood Pressure clinical trials

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NCT ID: NCT03443596 Recruiting - Blood Pressure Clinical Trials

Blood Pressure Control in Acute Ischemic Stroke

BP-Stroke
Start date: December 2014
Phase: Phase 2/Phase 3
Study type: Interventional

Management of acutely elevated blood pressure during the early phase of ischemic stroke remains controversial. In patients treated with IV-tPA, the risk of ICH is closely related to the BP levels. However, intensive reduction of BP carries a theoretical risk of clinical deterioration by inducing cerebral hypoperfusion. Assessment of cerebral perfusion before and after BP reduction is one of the most scientific method to evaluate the safety (and potential benefits) of BP management in the acute phase of stroke. This project will impact practices and delivery of BP management during the acute phase of ischemic stroke. The findings would aid in designing phase 3 clinical trials will track clinical indicators, including the impact on functional outcomes as well as quality-of-life and cost-effectiveness.

NCT ID: NCT03443375 Completed - Physical Activity Clinical Trials

Exercise Periodization and Older Adults

Start date: January 2015
Phase: N/A
Study type: Interventional

The present study aimed at investigating the effects of two different resistance training protocols — nonperiodized (NP) and daily undulating periodization (DUP) — on hemodynamic, morphofunctional and cognitive parameters of robust older women. Methods: Forty-two older women were randomized allocated into one of the three experimental groups: NP, DUP, and control group (CG). Evaluations of the hemodynamic, morphofunctional and cognitive parameters occurred before, during and after six months. The exercise groups performed the program of exercise twice a week over 22 weeks. In NP, the two weekly sessions were based on 3 sets of 8-10 repetitions at a difficult intensity. However, in DUP, a power exercise session based on 3 sets of 8-10 repetitions at a moderate intensity was added in the first session of the week.

NCT ID: NCT03442907 Not yet recruiting - Blood Pressure Clinical Trials

Personalized Blood Pressure Management

IMPROVE
Start date: March 1, 2018
Phase: N/A
Study type: Interventional

The aim of this research project is to find out whether a personalized definition of the lower blood pressure threshold based on the individual blood pressure profile by means of preoperative 24-hour blood pressure measurement can reduce organ damage (brain, kidney, heart) through reduced blood flow during surgery.

NCT ID: NCT03433963 Recruiting - Blood Pressure Clinical Trials

The Use of L-arginine to Mitigate the Cardiovascular Effects of Exposure to Traffic-related Air Pollution

Start date: January 2, 2018
Phase: N/A
Study type: Interventional

The present study is aimed to investigate whether oral L-arginine supplementation reduces the adverse cardiovascular effects of exposure to traffic-related air pollution among a group of non-smoking adults with elevated blood pressure.

NCT ID: NCT03431064 Not yet recruiting - Anesthesia Clinical Trials

Lung Recruitment Maneuver as a Potential Predictor of Fluid Responsiveness in Mechanically Ventilated Pediatric Patients

Start date: March 1, 2018
Phase: N/A
Study type: Observational

In this research study we want to learn more about using non-invasive tools as a way to predict whether or not a child under general anesthesia will require and respond to fluid administration. It is important for an anesthesiologist to know if a child would respond to fluid administration so that they can provide the optimal intervention for low blood pressure and avoid unnecessary treatment.

NCT ID: NCT03426774 Enrolling by invitation - Physical Activity Clinical Trials

Simulated Passive Jogging & Jumping Devices & NO

Start date: March 1, 2017
Phase: N/A
Study type: Interventional

Movement is important for overall health. Lack of movement has been shown to be associated with numerous diseases. This study will assess the validity and usefulness of two innovative low risk, non-invasive wellness devices, the Gentle Jogger® and the Gentle Jumper that passively simulate the physical activities of jogging and jumping, respectively. The study will evaluate whether or not each of the devices in different body postures (seated, lying down, slight recumbent and slight head down) produces changes in blood pressure, and indices of dilatation of blood vessels, in a younger (25-59yr) and older (> 60 yrs.) subject population. Volunteers will be paid for their participation in the study.

NCT ID: NCT03410342 Active, not recruiting - Blood Pressure Clinical Trials

The Effects of Types of Fruits and Vegetables on Vascular Function

CIRCUS
Start date: September 4, 2017
Phase: N/A
Study type: Interventional

The CIRCUS study is a randomised controlled, cross-over trial to evaluate the effects of increased intakes of citrus fruits and cruciferous vegetables on vascular function in 20 untreated, prehypertensive participants. The study comprises three 14-day dietary intervention periods, preceded by one week run-in period and separated by one week wash-out periods, 9 weeks in total. The diet will be fully controlled and provided by the researchers. Participants will receive in random order three interventions: - 1 portion of fruits plus 1 portion of vegetables, of commonly consumed types per day. Intakes are at 25th percentile of UK consumption and will exclude citrus fruits, cruciferous and allium vegetables. - 4 portions of fruits plus 4 portions of vegetables, of commonly consumed types per day excluding citrus fruits, cruciferous and allium vegetables. - 4 portions of citrus fruits plus 4 portions of cruciferous vegetables per day.

NCT ID: NCT03409861 Not yet recruiting - Blood Pressure Clinical Trials

`Wristband Device for the Measurement of Intermittent Blood Pressure and Other Physiological Signals

Start date: January 2018
Phase: N/A
Study type: Observational

A wristband device intended for use as a standalone device, designed for the measurement of intermittent blood pressure, as well as other physiological signals. The device is intended to be worn in day to day life by individuals suffering from hypertension or other conditions where monitoring of blood pressure is of importance.

NCT ID: NCT03404999 Enrolling by invitation - Hypertension Clinical Trials

Clinical-Decision Support to Improve Hypertension Care in Primary Care

Start date: August 21, 2017
Phase: N/A
Study type: Interventional

Approaches are needed to help primary-care pediatricians address high blood pressure. This study will test whether an electronic health-record-based tool to address high blood pressure is feasible and improves the evaluation and management of high blood pressure in clinical practice. If successful, this approach can be used to address other lifestyle-related and complex health problems (e.g., dyslipidemia and diabetes), then disseminated and used nationwide. The investigators have developed a new, electronic health-record (EHR)-based tool that is designed to help pediatricians: 1. IDENTIFY AND DOCUMENT 1. when a child's blood pressure is elevated, and 2. whether it has been elevated before--including number of prior elevations to document the correct diagnosis (for example, elevated blood pressure, vs. hypertension stage 1, vs. hypertension stage 2), THEN 2. ORDER the next action(s) needed per guideline-based recommendations, AND per prior actions taken--including: 1. laboratories and studies per 2017 updated guidelines 2. follow-up interval in primary care 3. referral to nephrology, when indicated, and 4. patient education on diet/lifestyle modification. The investigators are working on improving this system further with addition of orders for: 1. referral for sleep-apnea testing and treatment, when indicated, and 2. blood-pressure medications (for example, initiation, titration, or addition of agents depending on blood-pressure control, comorbid conditions [e.g., diabetes], and risk for pregnancy)

NCT ID: NCT03403166 Completed - Blood Pressure Clinical Trials

Metabolomics of the Dietary Approaches to Stop Hypertension (DASH) Dietary Pattern

Start date: August 1993
Phase: N/A
Study type: Observational

The present record represents a secondary data analysis of the Dietary Approaches to Stop Hypertension (DASH) trial. Study data and specimens were accessed through the National Heart, Lung, and Blood Institute (NHLBI) Biologic Specimen and Data Repository Coordinating Center (BioLINCC). A global, untargeted, metabolomic profile was used to investigate biomarkers of the DASH dietary pattern as well as blood pressure change.