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NCT ID: NCT05980013 Completed - Blood Loss Clinical Trials

Evaluation of Physiological Variables and Detection of Blood Loss in Healthy Adults With Different Subject Positioning by the CM-1500

Start date: August 28, 2023
Phase: N/A
Study type: Interventional

The study is a prospective, non-randomized, non-blinded, non-significant risk study enrolling up to 60 healthy adult subjects consented to undergo a 1-unit whole blood draw procedure. Subjects will wear the study device (CM-1500) while positioned in either a supine or reclined position during the blood draw and study-required physiological parameters will be captured pre-, during, and post-donation.

NCT ID: NCT05980000 Recruiting - HNSCC Clinical Trials

Ramucirumab and Pembrolizumab vs Pembrolizumab Monotherapy in PD-L1 Positive Head and Neck Squamous-Cell Carcinoma

Rambro2
Start date: October 27, 2023
Phase: Phase 2
Study type: Interventional

This is a phase 2 study investigating the efficacy of ramucirumab in combination with pembrolizumab compared to pembrolizumab monotherapy. Ramucirumab is a VEGFR-2 inhibitor believed to potentially enhance the efficacy of PD-1 inhibitors such as pembrolizumab.

NCT ID: NCT05979987 Active, not recruiting - Cancer Clinical Trials

UCLA Health Patient Health Maintenance Text Reminder July 2023

Start date: July 27, 2023
Phase: N/A
Study type: Interventional

This is a prospective randomized clinical trial evaluating how behaviorally-informed outreach text message reminders impact patient engagement with primary care. This prospective randomized control trial is being implemented in conjunction with UCLA Health's larger quality improvement initiative (the My Action Plan Quality Improvement Initiative) in order to improve primary care preventive measure completion rates.

NCT ID: NCT05979922 Active, not recruiting - Caregiver Stress Clinical Trials

Mindfulness-based Cognitive Coping for ADRD Caregivers

Start date: July 27, 2023
Phase: Phase 2
Study type: Interventional

This project will evaluate the effectiveness of the Mindfulness-based Cognitive Coping (MCC) intervention to alleviate stress and depressive symptoms of caregivers of Individuals with Alzheimer's Disease and Related Dementia.

NCT ID: NCT05979883 Recruiting - Cancer Head Neck Clinical Trials

Randomized Evaluation of Machine Learning Assisted Radiation Treatment Planning vs Standard Radiation Treatment Planning

Start date: August 7, 2023
Phase: N/A
Study type: Interventional

The purpose of this study is to determine the magnitude of clinical benefit achieved through machine learning assisted radiation treatment planning (MLAP) on post-treatment clinical outcomes such as acute toxicity and patient reported outcomes.

NCT ID: NCT05979844 Recruiting - PTSD Clinical Trials

MDMA-assisted Brief Cognitive Behavioral Conjoint Therapy for PTSD

MDMA-bCBCT
Start date: October 6, 2023
Phase: Phase 3
Study type: Interventional

The goal of this pilot trial is to examine the preliminary effectiveness of MDMA-facilitated bCBCT for improving chronic PTSD and relationship functioning in a sample of veterans and their intimate partners seeking care within the VA San Diego Healthcare System.

NCT ID: NCT05979779 Recruiting - Clinical trials for Non-Alcoholic Fatty Liver Disease

Ph 2 Study of the Safety and Efficacy of Three HU6 Dose Levels and Placebo in Nonalcoholic Steatohepatitis

Start date: September 5, 2023
Phase: Phase 2
Study type: Interventional

This is a phase 2 randomized, double-blind, placebo-controlled parallel group study of 3 dose levels of HU6 in subjects with nonalcoholic steatohepatitis (NASH). Six months (26 weeks) of dosing is planned, and subjects will be followed for safety, efficacy, pharmacodynamics (PD), and pharmacokinetics (PK) during this time. The end-of-study visit will take place approximately 4 weeks after the last dose of the study drug (Week 30).

NCT ID: NCT05979714 Recruiting - HIV Infections Clinical Trials

The Cheeky Study: A Novel Delivery System for CAB-RPV LA

Start date: May 31, 2023
Phase: N/A
Study type: Interventional

This is a single-arm implementation study of a novel integrated delivery model of CAB-RPV LA for transwomen living with HIV.

NCT ID: NCT05979688 Recruiting - Clinical trials for Amyotrophic Lateral Sclerosis

Yogic Breathing Exercise for People With Amyotrophic Lateral Sclerosis

Start date: November 1, 2023
Phase: N/A
Study type: Interventional

The aim of this study is to understand how well a 6-week virtual yogic breathing exercise program (YBEP) will improve breathing, speech, and emotional well-being in people with amyotrophic lateral sclerosis (ALS).

NCT ID: NCT05979610 Recruiting - Cervical Cancer Clinical Trials

Using Reiki Therapy to Improve Symptoms Associated With Brachytherapy in Patients With Gynecological Malignancies

Reiki-Brachy
Start date: October 9, 2023
Phase: Phase 2
Study type: Interventional

The goal of this open label, randomized, controlled clinical trial is to assess the benefits of providing Reiki therapy to subjects receiving their first brachytherapy treatment for gynecological malignancies. Participants will either receive a session of Reiki therapy or usual care during the standard wait time between the placement of the brachytherapy device and brachytherapy treatment. Questionnaires will be administered at various time points on the day of the participant's first brachytherapy treatment as well as at the three month follow-up time point. Researchers will compare the intervention (Reiki therapy) and control (usual care) groups to assess the impact of the Reiki therapy on anxiety, pain, state anxiety, depression, and physiological measurements.