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NCT ID: NCT04936334 Completed - Prostate Cancer Clinical Trials

The Role of 68Ga-PSMA-11 PET (Prostate Specific Membrane Antigen) in Surgery Guidance in Prostate Cancer

Start date: June 11, 2021
Phase: Phase 2
Study type: Interventional

Obtain PSMA-PET imaging preoperatively and calculate performance for predicting extra-prostatic extension based on whole-mount pathology (gold standard). Quantify the frequency of proper treatment changes directed by PSMA-PET, focusing on appropriate preservation of surrounding structures important for genito-urinary function including: 1) Bladder neck, 2) Nerve bundles, 3) Urethral Sphincter (Figure 4). Directly compare PSMA-PET performance for predicting extra-prostatic extension to standard-of-care assessments. Assess quality of life changes from preoperative baseline.

NCT ID: NCT04936256 Completed - Cataract Clinical Trials

Evaluation of Binocular Visual Acuity and Refractive Stability in the Alcon Clareon Intraocular Lens

Start date: July 2, 2021
Phase:
Study type: Observational

The objective is to evaluate refractive stability (spherical equivalent change ≤ 0.50D from 1-month to 3-months).

NCT ID: NCT04936243 Completed - Breast Cancer Clinical Trials

TIPOPS (Telemedicine vs In Person Oncology Patient Surveillance)

Start date: August 1, 2021
Phase: N/A
Study type: Interventional

This research study is comparing telemedicine and face-to-face visits to understand patients' experiences with telemedicine versus face to face visits and to understand when it is and is not appropriate to conduct visits remotely

NCT ID: NCT04935931 Completed - Eating Disorders Clinical Trials

Naltrexone Neuroimaging

EDIT-N2
Start date: July 16, 2021
Phase: Early Phase 1
Study type: Interventional

The purpose of this open-label, pilot study is to evaluate fMRI as a biomarker of opioid antagonism in adolescents with ED. Modulation of brain activation will be examined in regions of interest by fMRI using a food-specific and general reward task in adolescents with ED in a pre/post design.

NCT ID: NCT04935892 Completed - Clinical trials for Transmission, Other/Miscellaneous

Slippers to Reduce Transfer From Floors to Surfaces

Start date: August 1, 2020
Phase: N/A
Study type: Interventional

The goal of this study is to determine if wearing slippers will reduce transfer of bacteriophage MS2 from hospital room floors to surfaces in the room and hands of patients. Subjects are randomized to wear slippers versus standard care and cultures are collected at 24 and 48 hours to assess transfer of bacteriophage MS2 from the floor to high-touch surfaces, personal items, bedding, socks or feet, and hands of patients.

NCT ID: NCT04935775 Completed - Anxiety Clinical Trials

The Effect of Touch on Pain and Anxiety During the Bone Marrow Biopsy Procedure

Dixon Project
Start date: October 13, 2021
Phase: N/A
Study type: Interventional

This study is analyzing the benefit of untrained touch provided during a bone marrow biopsy procedure as compared to performing the procedure without providing it.

NCT ID: NCT04935463 Completed - Covid19 Clinical Trials

Mucormycosis in COVID-19

MUNCO
Start date: May 24, 2021
Phase:
Study type: Observational

The purpose is to allow phsyician reporters to contribute to MUNCO registry. Mucormycosis in COVID-19 is a rapidly escalating medical emergency reported in high numbers in India during the ongoing coronavirus surge. There is very little known about the risk factors, patterns and complications of mucormycosis as it occurs either during the infection or treatment phase of the novel coronavirus (COVID-19). In light of this emerging epidemic within a pandemic, it is of time sensitive importance to obtain a better understanding of the risk factors and outcomes of this fatal complication

NCT ID: NCT04935294 Completed - Healthy Clinical Trials

Study of Danicopan in Participants With Normal Kidney Function and Participants With Kidney Dysfunction

Start date: January 24, 2018
Phase: Phase 1
Study type: Interventional

This was an open-label, nonrandomized, multi-center, single-dose, parallel group study to evaluate the effect of severe renal impairment (RI) on the safety, tolerability, pharmacokinetics, and pharmacodynamics of danicopan (ACH-0144471) compared to demographically-matched healthy participants with normal renal function.

NCT ID: NCT04935112 Completed - Healthy Adults Clinical Trials

A Study to Explore the Effect of Acid-reducing Agents

Start date: July 7, 2021
Phase: Phase 1
Study type: Interventional

A Phase 1 Study of the Effect of Acid-reducing Agents on the Pharmacokinetics of a Single Oral Dose of Sitravatinib in Healthy Adult Subjects. The study is a single-center, open-label, 2-period, 2-treatment, fixed-sequence crossover, parallel-group study.

NCT ID: NCT04934969 Completed - Joint Diseases Clinical Trials

The Adjunctive Use of Lavender and Peppermint Essential Oils

aromatherapy
Start date: July 30, 2021
Phase: N/A
Study type: Interventional

This study will use passive inhalation of lavender for discomfort, anxiety and peppermint for nausea following joint replacement and spine surgery