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NCT ID: NCT03712371 Terminated - Prostate Cancer Clinical Trials

Study of Chitosan for Pharmacologic Manipulation of AGE (Advanced Glycation Endproducts) Levels in Prostate Cancer Patients

Start date: January 16, 2019
Phase: Phase 1/Phase 2
Study type: Interventional

This study will examine the utility of chitosan for reduction of blood or tissue levels of AGEs in patients with prostate cancer who are clinically stable on androgen-deprivation therapy.

NCT ID: NCT03712345 Terminated - Clinical trials for Microscopic Polyangiitis (MPA)

Safety and Efficacy Study of IFX-1 in add-on to Standard of Care in GPA and MPA

Start date: October 15, 2018
Phase: Phase 2
Study type: Interventional

The purpose of this study is to investigate the safety and tolerability of two dose regimens of IFX-1 as add-on to standard of care (SOC) in subjects with GPA and MPA compared with placebo.

NCT ID: NCT03711994 Terminated - Post Operative Pain Clinical Trials

Cold Therapy for Pain Control Following Caesarean Section

Start date: December 2015
Phase: N/A
Study type: Interventional

Cold Therapy has been used for a variety of procedures and has been studied in several but not recently studied for reducing postop pain following Caesarean Sections. The hypothesis is that Cold Therapy will reduce postop pain and increase patients mobility and improve care of her newborn.

NCT ID: NCT03711929 Terminated - Clinical trials for Non Infectious Uveitis

LUMINA Phase III Study Assessing the Efficacy and Safety of Intravitreal Injections of 440 ug DE-109 Sirolimus for the Treatment of Active, Non-Infectious Uveitis of the Posterior Segment of the Eye

Start date: November 19, 2018
Phase: Phase 3
Study type: Interventional

This is a Phase III study to assess the efficacy and safety of DE-109 440 µg every 2 months in subjects with active, non-infectious uveitis of the posterior segment of the eye (NIU-PS). There is a 6-month, single-arm, open-label period after completion of the 6-month double- masked, controlled period allows the evaluation of the efficacy and safety of intravitreal injection of DE-109 440 µg every 2 months for longer duration than appropriate for a placebo or sham control.

NCT ID: NCT03711591 Terminated - Clinical trials for Proximal Humeral Fracture

Single Center Post Approval Proximal Humerus Fixation With the Conventus Cage PH™ Device

Start date: November 29, 2018
Phase:
Study type: Observational

The Conventus CAGE™ PH (PH Cage) System Post-Approval Observational Data Collection Study (Study) is a single center, prospective, post-approval clinical study designed to collect device and procedure experience in everyday clinical practice.

NCT ID: NCT03711318 Terminated - Heroin Dependence Clinical Trials

Buprenorphine Stabilization and Induction Onto Vivitrol for Heroin-dependent Individuals

Start date: November 1, 2018
Phase: Phase 3
Study type: Interventional

A short-term treatment with buprenorphine prior to initiating treatment with naltrexone may increase the proportion of heroin-dependent patients successfully inducted onto Vivitrol.

NCT ID: NCT03711162 Terminated - Clinical trials for Idiopathic Pulmonary Fibrosis

A Clinical Study to Test How Effective and Safe GLPG1690 is for Subjects With Idiopathic Pulmonary Fibrosis (IPF) When Used Together With Standard of Care

ISABELA1
Start date: November 28, 2018
Phase: Phase 3
Study type: Interventional

The main purpose of this study was to see how GLPG1690 works together with your current standard treatment on your lung function and IPF disease in general. The study also investigated how well GLPG1690 is tolerated (for example if you got any side effects while on study drug).

NCT ID: NCT03710564 Terminated - Clinical trials for Age-Related Macular Degeneration

Study of Safety and Efficacy of Brolucizumab 6 mg Dosed Every 4 Weeks Compared to Aflibercept 2 mg Dosed Every 4 Weeks in Patients With Retinal Fluid Despite Frequent Anti-VEGF Injections

MERLIN
Start date: October 30, 2018
Phase: Phase 3
Study type: Interventional

This clinical study was designed to compare the safety and efficacy of brolucizumab 6 mg dosed every 4 weeks to aflibercept 2 mg dosed every 4 weeks in those neovascular age-related macular degeneration (nAMD) patients with retinal fluid despite frequent anti-Vascular Endothelial Growth Factor (VEGF) injections.

NCT ID: NCT03710291 Terminated - Clinical trials for Chronic Kidney Disease

Evaluation of Effect of TRC101 on Progression of Chronic Kidney Disease in Subjects With Metabolic Acidosis

VALOR-CKD
Start date: November 20, 2018
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the effect of TRC101 on the progression of chronic kidney disease (CKD) and to evaluate the safety profile of TRC101 in CKD patients with metabolic acidosis.

NCT ID: NCT03710161 Terminated - Clinical trials for Kidney Failure, Chronic

Effect of Vitamin D Supplementation on Balance in CKD

Start date: July 8, 2019
Phase: Phase 4
Study type: Interventional

Patients with end-stage renal disease on dialysis (ESRD5D) are 4-5x more likely to suffer from a fracture. Fractures can occur spontaneously but typically occur after a fall. Further, 70-90% of patients with ESRD5D are vitamin D deficient. Vitamin D supplementation has become routine care for many in this patient population, but evidence is lacking to support this practice. The proposed projects objective is to gather needed preliminary data regarding the effects of vitamin D supplementation on balance and muscle strength in patients with ESRD5D.